Impact of stressor exposure on the interplay between commensal microbiota and host inflammation

References

• Huffnagle GB. The microbiota and allergies/asthma. PLoS Pathog 2010; 6:e1000549; http://dx.doi.org/10.1371/journal.ppat.1000549; PMID: 20523892
   PubMedGoogle Scholar
• Bäckhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI. Host-bacterial mutualism in the human intestine. Science 2005; 307:1915 - 20; http://dx.doi.org/10.1126/science.1104816; PMID: 15790844
   PubMed Web of Science ®Google Scholar
• Reinhardt C, Bergentall M, Greiner TU, Schaffner F, Ostergren-Lundén G, Petersen LC, Ruf W, Bäckhed F. Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling. Nature 2012; 483:627 - 31; http://dx.doi.org/10.1038/nature10893; PMID: 22407318
   PubMed Web of Science ®Google Scholar
• Tomas J, Wrzosek L, Bouznad N, Bouet S, Mayeur C, Noordine ML, Honvo-Houeto E, Langella P, Thomas M, Cherbuy C. Primocolonization is associated with colonic epithelial maturation during conventionalization. FASEB J 2013; 27:645 - 55; http://dx.doi.org/10.1096/fj.12-216861; PMID: 23118025
   PubMed Web of Science ®Google Scholar
• Bäckhed F, Ding H, Wang T, Hooper LV, Koh GY, Nagy A, Semenkovich CF, Gordon JI. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A 2004; 101:15718 - 23; http://dx.doi.org/10.1073/pnas.0407076101; PMID: 15505215
   PubMed Web of Science ®Google Scholar
• Sayin SI, Wahlström A, Felin J, Jäntti S, Marschall HU, Bamberg K, Angelin B, Hyötyläinen T, Orešič M, Bäckhed F. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab 2013; 17:225 - 35; http://dx.doi.org/10.1016/j.cmet.2013.01.003; PMID: 23395169
   PubMed Web of Science ®Google Scholar
• Resta SC. Effects of probiotics and commensals on intestinal epithelial physiology: implications for nutrient handling. J Physiol 2009; 587:4169 - 74; http://dx.doi.org/10.1113/jphysiol.2009.176370; PMID: 19596893
   PubMed Web of Science ®Google Scholar
• Bercik P, Denou E, Collins J, Jackson W, Lu J, Jury J, Deng Y, Blennerhassett P, Macri J, McCoy KD, et al. The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice. Gastroenterology 2011; 141:599 - 609, e1-3; http://dx.doi.org/10.1053/j.gastro.2011.04.052; PMID: 21683077
   PubMed Web of Science ®Google Scholar
• Diaz Heijtz R, Wang S, Anuar F, Qian Y, Björkholm B, Samuelsson A, Hibberd ML, Forssberg H, Pettersson S. Normal gut microbiota modulates brain development and behavior. Proc Natl Acad Sci U S A 2011; 108:3047 - 52; http://dx.doi.org/10.1073/pnas.1010529108; PMID: 21282636
   PubMed Web of Science ®Google Scholar
• Hansen CH, Nielsen DS, Kverka M, Zakostelska Z, Klimesova K, Hudcovic T, Tlaskalova-Hogenova H, Hansen AK. Patterns of early gut colonization shape future immune responses of the host. PLoS One 2012; 7:e34043; http://dx.doi.org/10.1371/journal.pone.0034043; PMID: 22479515
   PubMed Web of Science ®Google Scholar
• El Aidy S, van Baarlen P, Derrien M, Lindenbergh-Kortleve DJ, Hooiveld G, Levenez F, Doré J, Dekker J, Samsom JN, Nieuwenhuis EE, et al. Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice. Mucosal Immunol 2012; 5:567 - 79; http://dx.doi.org/10.1038/mi.2012.32; PMID: 22617837
   PubMed Web of Science ®Google Scholar
• Shichijo K, Ito M, Taniyama K, Sekine I. The role of sympathetic neurons for low susceptibility to stress in gastric lesions. Life Sci 1993; 53:261 - 7; http://dx.doi.org/10.1016/0024-3205(93)90677-U; PMID: 8321086
   PubMed Web of Science ®Google Scholar
• Yang H, Yuan PQ, Wang L, Taché Y. Activation of the parapyramidal region in the ventral medulla stimulates gastric acid secretion through vagal pathways in rats. Neuroscience 2000; 95:773 - 9; http://dx.doi.org/10.1016/S0306-4522(99)00490-X; PMID: 10670444
   PubMed Web of Science ®Google Scholar
• Nakade Y, Tsuchida D, Fukuda H, Iwa M, Pappas TN, Takahashi T. Restraint stress delays solid gastric emptying via a central CRF and peripheral sympathetic neuron in rats. Am J Physiol Regul Integr Comp Physiol 2005; 288:R427 - 32; http://dx.doi.org/10.1152/ajpregu.00499.2004; PMID: 15458973
   PubMed Web of Science ®Google Scholar
• Wang SX, Wu WC. Effects of psychological stress on small intestinal motility and bacteria and mucosa in mice. World J Gastroenterol 2005; 11:2016 - 21; PMID: 15800998
   PubMed Web of Science ®Google Scholar
• Nakade Y, Fukuda H, Iwa M, Tsukamoto K, Yanagi H, Yamamura T, Mantyh C, Pappas TN, Takahashi T. Restraint stress stimulates colonic motility via central corticotropin-releasing factor and peripheral 5-HT3 receptors in conscious rats. Am J Physiol Gastrointest Liver Physiol 2007; 292:G1037 - 44; http://dx.doi.org/10.1152/ajpgi.00419.2006; PMID: 17158256
   PubMed Web of Science ®Google Scholar
• Castagliuolo I, Lamont JT, Qiu B, Fleming SM, Bhaskar KR, Nikulasson ST, Kornetsky C, Pothoulakis C. Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells. Am J Physiol 1996; 271:G884 - 92; PMID: 8944704
   PubMed Web of Science ®Google Scholar
• Jarillo-Luna A, Rivera-Aguilar V, Garfias HR, Lara-Padilla E, Kormanovsky A, Campos-Rodríguez R. Effect of repeated restraint stress on the levels of intestinal IgA in mice. Psychoneuroendocrinology 2007; 32:681 - 92; http://dx.doi.org/10.1016/j.psyneuen.2007.04.009; PMID: 17590521
   PubMed Web of Science ®Google Scholar
• Drasar BS, Shiner M, McLeod GM. Studies on the intestinal flora. I. The bacterial flora of the gastrointestinal tract in healthy and achlorhydric persons. Gastroenterology 1969; 56:71 - 9; PMID: 4885396
   PubMed Web of Science ®Google Scholar
• Nieuwenhuijs VB, Verheem A, van Duijvenbode-Beumer H, Visser MR, Verhoef J, Gooszen HG, Akkermans LM. The role of interdigestive small bowel motility in the regulation of gut microflora, bacterial overgrowth, and bacterial translocation in rats. Ann Surg 1998; 228:188 - 93; http://dx.doi.org/10.1097/00000658-199808000-00007; PMID: 9712563
   PubMed Web of Science ®Google Scholar
• Derrien M, Vaughan EE, Plugge CM, de Vos WM. Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. Int J Syst Evol Microbiol 2004; 54:1469 - 76; http://dx.doi.org/10.1099/ijs.0.02873-0; PMID: 15388697
   PubMed Web of Science ®Google Scholar
• Bailey MT, Karaszewski JW, Lubach GR, Coe CL, Lyte M. In vivo adaptation of attenuated Salmonella typhimurium results in increased growth upon exposure to norepinephrine. Physiol Behav 1999; 67:359 - 64; http://dx.doi.org/10.1016/S0031-9384(99)00087-6; PMID: 10497953
   PubMed Web of Science ®Google Scholar
• Pullinger GD, Carnell SC, Sharaff FF, van Diemen PM, Dziva F, Morgan E, Lyte M, Freestone PP, Stevens MP. Norepinephrine augments Salmonella enterica-induced enteritis in a manner associated with increased net replication but independent of the putative adrenergic sensor kinases QseC and QseE. Infect Immun 2010; 78:372 - 80; http://dx.doi.org/10.1128/IAI.01203-09; PMID: 19884332
   PubMed Web of Science ®Google Scholar
• Green BT, Lyte M, Chen C, Xie Y, Casey MA, Kulkarni-Narla A, Vulchanova L, Brown DR. Adrenergic modulation of Escherichia coli O157:H7 adherence to the colonic mucosa. Am J Physiol Gastrointest Liver Physiol 2004; 287:G1238 - 46; http://dx.doi.org/10.1152/ajpgi.00471.2003; PMID: 15534374
   PubMed Web of Science ®Google Scholar
• Tannock GW, Savage DC. Influences of dietary and environmental stress on microbial populations in the murine gastrointestinal tract. Infect Immun 1974; 9:591 - 8; PMID: 4593471
   PubMed Web of Science ®Google Scholar
• Bailey MT, Coe CL. Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys. Dev Psychobiol 1999; 35:146 - 55; http://dx.doi.org/10.1002/(SICI)1098-2302(199909)35:2<146::AID-DEV7>3.0.CO;2-G; PMID: 10461128
   PubMed Web of Science ®Google Scholar
• Bailey MT, Lubach GR, Coe CL. Prenatal stress alters bacterial colonization of the gut in infant monkeys. J Pediatr Gastroenterol Nutr 2004; 38:414 - 21; http://dx.doi.org/10.1097/00005176-200404000-00009; PMID: 15085020
   PubMed Web of Science ®Google Scholar
• Knowles SR, Nelson EA, Palombo EA. Investigating the role of perceived stress on bacterial flora activity and salivary cortisol secretion: a possible mechanism underlying susceptibility to illness. Biol Psychol 2008; 77:132 - 7; http://dx.doi.org/10.1016/j.biopsycho.2007.09.010; PMID: 18023961
   PubMed Web of Science ®Google Scholar
• O’Mahony SM, Marchesi JR, Scully P, Codling C, Ceolho AM, Quigley EM, Cryan JF, Dinan TG. Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses. Biol Psychiatry 2009; 65:263 - 7; http://dx.doi.org/10.1016/j.biopsych.2008.06.026; PMID: 18723164
   PubMed Web of Science ®Google Scholar
• Bailey MT, Dowd SE, Parry NM, Galley JD, Schauer DB, Lyte M. Stressor exposure disrupts commensal microbial populations in the intestines and leads to increased colonization by Citrobacter rodentium.. Infect Immun 2010; 78:1509 - 19; http://dx.doi.org/10.1128/IAI.00862-09; PMID: 20145094
   PubMed Web of Science ®Google Scholar
• Bailey MT, Dowd SE, Galley JD, Hufnagle AR, Allen RG, Lyte M. Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation. Brain Behav Immun 2011; 25:397 - 407; http://dx.doi.org/10.1016/j.bbi.2010.10.023; PMID: 21040780
   PubMed Web of Science ®Google Scholar
• Roberts CJ, Campbell IC, Troop N. Increases in weight during chronic stress are partially associated with a switch in food choice towards increased carbohydrate and saturated fat intake. Eur Eat Disord Rev 2014; 22:77 - 82; http://dx.doi.org/10.1002/erv.2264; PMID: 24123563
   PubMed Web of Science ®Google Scholar
• Sanghez V, Razzoli M, Carobbio S, Campbell M, McCallum J, Cero C, Ceresini G, Cabassi A, Govoni P, Franceschini P, et al. Psychosocial stress induces hyperphagia and exacerbates diet-induced insulin resistance and the manifestations of the Metabolic Syndrome. Psychoneuroendocrinology 2013; 38:2933 - 42; http://dx.doi.org/10.1016/j.psyneuen.2013.07.022; PMID: 24060458
   PubMed Web of Science ®Google Scholar
• Krahn DD, Gosnell BA, Grace M, Levine AS. CRF antagonist partially reverses CRF- and stress-induced effects on feeding. Brain Res Bull 1986; 17:285 - 9; http://dx.doi.org/10.1016/0361-9230(86)90233-9; PMID: 3490298
   PubMed Web of Science ®Google Scholar
• Lau C, Simpson C. Animal models for the study of the effect of prolonged stress on lactation in rats. Physiol Behav 2004; 82:193 - 7; http://dx.doi.org/10.1016/j.physbeh.2004.05.004; PMID: 15276780
   PubMed Web of Science ®Google Scholar
• Aguggia JP, Suárez MM, Rivarola MA. Early maternal separation: neurobehavioral consequences in mother rats. Behav Brain Res 2013; 248:25 - 31; http://dx.doi.org/10.1016/j.bbr.2013.03.040; PMID: 23567892
   PubMed Web of Science ®Google Scholar
• Goyal N, Shukla G. Probiotic Lactobacillus rhamnosus GG modulates the mucosal immune response in Giardia intestinalis-infected BALB/c mice. Dig Dis Sci 2013; 58:1218 - 25; http://dx.doi.org/10.1007/s10620-012-2503-y; PMID: 23263901
   PubMed Web of Science ®Google Scholar
• Thomas CM, Hong T, van Pijkeren JP, Hemarajata P, Trinh DV, Hu W, Britton RA, Kalkum M, Versalovic J. Histamine derived from probiotic Lactobacillus reuteri suppresses TNF via modulation of PKA and ERK signaling. PLoS One 2012; 7:e31951; http://dx.doi.org/10.1371/journal.pone.0031951; PMID: 22384111
   PubMed Web of Science ®Google Scholar
• Mackos AR, Eubank TD, Parry NM, Bailey MT. Probiotic Lactobacillus reuteri attenuates the stressor-enhanced severity of Citrobacter rodentium infection. Infect Immun 2013; 81:3253 - 63; http://dx.doi.org/10.1128/IAI.00278-13; PMID: 23798531
   PubMed Web of Science ®Google Scholar
• Sudo N, Chida Y, Aiba Y, Sonoda J, Oyama N, Yu XN, Kubo C, Koga Y. Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J Physiol 2004; 558:263 - 75; http://dx.doi.org/10.1113/jphysiol.2004.063388; PMID: 15133062
   PubMed Web of Science ®Google Scholar
• Padgett DA, Glaser R. How stress influences the immune response. Trends Immunol 2003; 24:444 - 8; http://dx.doi.org/10.1016/S1471-4906(03)00173-X; PMID: 12909458
   PubMed Web of Science ®Google Scholar
• Reber SO, Birkeneder L, Veenema AH, Obermeier F, Falk W, Straub RH, Neumann ID. Adrenal insufficiency and colonic inflammation after a novel chronic psycho-social stress paradigm in mice: implications and mechanisms. Endocrinology 2007; 148:670 - 82; http://dx.doi.org/10.1210/en.2006-0983; PMID: 17110427
   PubMed Web of Science ®Google Scholar
• Barouei J, Moussavi M, Hodgson DM. Effect of maternal probiotic intervention on HPA axis, immunity and gut microbiota in a rat model of irritable bowel syndrome. PLoS One 2012; 7:e46051; http://dx.doi.org/10.1371/journal.pone.0046051; PMID: 23071537
   PubMedGoogle Scholar
• Desbonnet L, Garrett L, Clarke G, Kiely B, Cryan JF, Dinan TG. Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience 2010; 170:1179 - 88; http://dx.doi.org/10.1016/j.neuroscience.2010.08.005; PMID: 20696216
   PubMed Web of Science ®Google Scholar
• Messaoudi M, Lalonde R, Violle N, Javelot H, Desor D, Nejdi A, Bisson JF, Rougeot C, Pichelin M, Cazaubiel M, et al. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. Br J Nutr 2011; 105:755 - 64; http://dx.doi.org/10.1017/S0007114510004319; PMID: 20974015
   PubMed Web of Science ®Google Scholar
• Bernstein CN, Singh S, Graff LA, Walker JR, Miller N, Cheang M. A prospective population-based study of triggers of symptomatic flares in IBD. Am J Gastroenterol 2010; 105:1994 - 2002; http://dx.doi.org/10.1038/ajg.2010.140; PMID: 20372115
   PubMed Web of Science ®Google Scholar
• Sokol H, Seksik P, Furet JP, Firmesse O, Nion-Larmurier I, Beaugerie L, Cosnes J, Corthier G, Marteau P, Doré J. Low counts of Faecalibacterium prausnitzii in colitis microbiota. Inflamm Bowel Dis 2009; 15:1183 - 9; http://dx.doi.org/10.1002/ibd.20903; PMID: 19235886
   PubMed Web of Science ®Google Scholar
• Machiels K, Joossens M, Sabino J, De Preter V, Arijs I, Eeckhaut V, Ballet V, Claes K, Van Immerseel F, Verbeke K, et al. A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. Gut 2013; http://dx.doi.org/10.1136/gutjnl-2013-304833; PMID: 24021287
   PubMed Web of Science ®Google Scholar
• Sokol H, Pigneur B, Watterlot L, Lakhdari O, Bermúdez-Humarán LG, Gratadoux JJ, Blugeon S, Bridonneau C, Furet JP, Corthier G, et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A 2008; 105:16731 - 6; http://dx.doi.org/10.1073/pnas.0804812105; PMID: 18936492
   PubMed Web of Science ®Google Scholar
• Martín R, Chain F, Miquel S, Lu J, Gratadoux JJ, Sokol H, Verdu EF, Bercik P, Bermúdez-Humarán LG, Langella P. The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models. Inflamm Bowel Dis 2014; 20:417 - 30; http://dx.doi.org/10.1097/01.MIB.0000440815.76627.64; PMID: 24418903
   PubMed Web of Science ®Google Scholar
• Söderholm JD, Yates DA, Gareau MG, Yang PC, MacQueen G, Perdue MH. Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress. Am J Physiol Gastrointest Liver Physiol 2002; 283:G1257 - 63; PMID: 12388189
   PubMed Web of Science ®Google Scholar
• Maslanik T, Tannura K, Mahaffey L, Loughridge AB, Benninson L, Ursell L, Greenwood BN, Knight R, Fleshner M. Commensal bacteria and MAMPs are necessary for stress-induced increases in IL-1β and IL-18 but not IL-6, IL-10 or MCP-1. PLoS One 2012; 7:e50636; http://dx.doi.org/10.1371/journal.pone.0050636; PMID: 23236381
   PubMedGoogle Scholar
• Allen RG, Lafuse WP, Galley JD, Ali MM, Ahmer BM, Bailey MT. The intestinal microbiota are necessary for stressor-induced enhancement of splenic macrophage microbicidal activity. Brain Behav Immun 2012; 26:371 - 82; http://dx.doi.org/10.1016/j.bbi.2011.11.002; PMID: 22100833
   PubMed Web of Science ®Google Scholar
• Abrams GD, Bishop JE. Effect of the normal microbial flora on gastrointestinal motility. Proc Soc Exp Biol Med 1967; 126:301 - 4; http://dx.doi.org/10.3181/00379727-126-32430; PMID: 6066182
   PubMed Web of Science ®Google Scholar
• Caenepeel P, Janssens J, Vantrappen G, Eyssen H, Coremans G. Interdigestive myoelectric complex in germ-free rats. Dig Dis Sci 1989; 34:1180 - 4; http://dx.doi.org/10.1007/BF01537265; PMID: 2752868
   PubMed Web of Science ®Google Scholar
• Anitha M, Vijay-Kumar M, Sitaraman SV, Gewirtz AT, Srinivasan S. Gut microbial products regulate murine gastrointestinal motility via Toll-like receptor 4 signaling. Gastroenterology 2012; 143:1006 - 16, e4; http://dx.doi.org/10.1053/j.gastro.2012.06.034; PMID: 22732731
   PubMed Web of Science ®Google Scholar
• Uribe A, Alam M, Johansson O, Midtvedt T, Theodorsson E. Microflora modulates endocrine cells in the gastrointestinal mucosa of the rat. Gastroenterology 1994; 107:1259 - 69; http://dx.doi.org/10.1016/0016-5085(94)90526-6; PMID: 7926490
   PubMed Web of Science ®Google Scholar
• Crouzet L, Gaultier E, Del’Homme C, Cartier C, Delmas E, Dapoigny M, Fioramonti J, Bernalier-Donadille A. The hypersensitivity to colonic distension of IBS patients can be transferred to rats through their fecal microbiota. Neurogastroenterol Motil 2013; 25:e272 - 82; http://dx.doi.org/10.1111/nmo.12103; PMID: 23433203
   PubMed Web of Science ®Google Scholar
• Amaral FA, Sachs D, Costa VV, Fagundes CT, Cisalpino D, Cunha TM, Ferreira SH, Cunha FQ, Silva TA, Nicoli JR, et al. Commensal microbiota is fundamental for the development of inflammatory pain. Proc Natl Acad Sci U S A 2008; 105:2193 - 7; http://dx.doi.org/10.1073/pnas.0711891105; PMID: 18268332
   PubMed Web of Science ®Google Scholar
• Petersson J, Schreiber O, Hansson GC, Gendler SJ, Velcich A, Lundberg JO, Roos S, Holm L, Phillipson M. Importance and regulation of the colonic mucus barrier in a mouse model of colitis. Am J Physiol Gastrointest Liver Physiol 2011; 300:G327 - 33; http://dx.doi.org/10.1152/ajpgi.00422.2010; PMID: 21109593
   PubMed Web of Science ®Google Scholar
• Wrzosek L, Miquel S, Noordine ML, Bouet S, Joncquel Chevalier-Curt M, Robert V, Philippe C, Bridonneau C, Cherbuy C, Robbe-Masselot C, et al. Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent. BMC Biol 2013; 11:61; http://dx.doi.org/10.1186/1741-7007-11-61; PMID: 23692866
   PubMed Web of Science ®Google Scholar
• Guo S, Gao Q, Jiao Q, Hao W, Gao X, Cao JM. Gastric mucosal damage in water immersion stress: mechanism and prevention with GHRP-6. World J Gastroenterol 2012; 18:3145 - 55; http://dx.doi.org/10.3748/wjg.v18.i24.3145; PMID: 22791951
   PubMed Web of Science ®Google Scholar
• Castagliuolo I, Lamont JT, Qiu B, Fleming SM, Bhaskar KR, Nikulasson ST, Kornetsky C, Pothoulakis C. Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells. Am J Physiol 1996; 271:G884 - 92; PMID: 8944704
   PubMed Web of Science ®Google Scholar
• Reyna-Garfias H, Miliar A, Jarillo-Luna A, Rivera-Aguilar V, Pacheco-Yepez J, Baeza I, Campos-Rodríguez R. Repeated restraint stress increases IgA concentration in rat small intestine. Brain Behav Immun 2010; 24:110 - 8; http://dx.doi.org/10.1016/j.bbi.2009.09.005; PMID: 19748568
   PubMed Web of Science ®Google Scholar
• Lewis K, Caldwell J, Phan V, Prescott D, Nazli A, Wang A, Soderhölm JD, Perdue MH, Sherman PM, McKay DM. Decreased epithelial barrier function evoked by exposure to metabolic stress and nonpathogenic E. coli is enhanced by TNFα. Am J Physiol Gastrointest Liver Physiol 2008; 294:G669 - 78; http://dx.doi.org/10.1152/ajpgi.00382.2007; PMID: 18187519
   PubMedGoogle Scholar
• Allen RG, Lafuse WP, Powell ND, Webster Marketon JI, Stiner-Jones LM, Sheridan JF, Bailey MT. Stressor-induced increase in microbicidal activity of splenic macrophages is dependent upon peroxynitrite production. Infect Immun 2012; 80:3429 - 37; http://dx.doi.org/10.1128/IAI.00714-12; PMID: 22825446
   PubMed Web of Science ®Google Scholar
• Galley JD, Nelson MC, Yu Z, Dowd SE, Walter J, Kumar PS, Lyte M, Bailey MT. Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota. BMC Microbiology 2014; 14:189; http://dx.doi.org/10.1186/1471-2180-14-189; PMID: 25028050
   PubMed Web of Science ®Google Scholar