2,633
Views
68
CrossRef citations to date
0
Altmetric
Research Paper

Characterization of mice expressing Ins1 gene promoter driven CreERT recombinase for conditional gene deletion in pancreatic β-cells

, &
Article: e27685 | Received 29 Apr 2013, Accepted 30 Dec 2013, Published online: 14 Jan 2014

References

  • Mallo M. Controlled gene activation and inactivation in the mouse. Front Biosci 2006; 11:313 - 27; http://dx.doi.org/10.2741/1799; PMID: 16146733
  • Postic C, Shiota M, Niswender KD, Jetton TL, Chen Y, Moates JM, Shelton KD, Lindner J, Cherrington AD, Magnuson MA. Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase. J Biol Chem 1999; 274:305 - 15; http://dx.doi.org/10.1074/jbc.274.1.305; PMID: 9867845
  • Zhang H, Fujitani Y, Wright CV, Gannon M. Efficient recombination in pancreatic islets by a tamoxifen-inducible Cre-recombinase. Genesis 2005; 42:210 - 7; http://dx.doi.org/10.1002/gene.20137; PMID: 15986486
  • Gu G, Dubauskaite J, Melton DA. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002; 129:2447 - 57; PMID: 11973276
  • Wiebe PO, Kormish JD, Roper VT, Fujitani Y, Alston NI, Zaret KS, Wright CV, Stein RW, Gannon M. Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression. Mol Cell Biol 2007; 27:4093 - 104; http://dx.doi.org/10.1128/MCB.01978-06; PMID: 17403901
  • Mori H, Inoki K, Münzberg H, Opland D, Faouzi M, Villanueva EC, Ikenoue T, Kwiatkowski D, MacDougald OA, Myers MG Jr., et al. Critical role for hypothalamic mTOR activity in energy balance. Cell Metab 2009; 9:362 - 74; http://dx.doi.org/10.1016/j.cmet.2009.03.005; PMID: 19356717
  • Hara M, Wang X, Kawamura T, Bindokas VP, Dizon RF, Alcoser SY, Magnuson MA, Bell GI. Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells. Am J Physiol Endocrinol Metab 2003; 284:E177 - 83; PMID: 12388130
  • Park SY, Wang X, Chen Z, Powers AC, Magnuson MA, Head WS, Piston DW, Bell GI. Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene. Genesis 2005; 43:80 - 6; http://dx.doi.org/10.1002/gene.20157; PMID: 16108006
  • Feil R, Brocard J, Mascrez B, LeMeur M, Metzger D, Chambon P. Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci U S A 1996; 93:10887 - 90; http://dx.doi.org/10.1073/pnas.93.20.10887; PMID: 8855277
  • Hayashi S, McMahon AP. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol 2002; 244:305 - 18; http://dx.doi.org/10.1006/dbio.2002.0597; PMID: 11944939
  • Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, et al. Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain. Diabetes 2010; 59:3090 - 8; http://dx.doi.org/10.2337/db10-0624; PMID: 20802254
  • Dessimoz J, Bonnard C, Huelsken J, Grapin-Botton A. Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development. Curr Biol 2005; 15:1677 - 83; http://dx.doi.org/10.1016/j.cub.2005.08.037; PMID: 16169491
  • Dabernat S, Secrest P, Peuchant E, Moreau-Gaudry F, Dubus P, Sarvetnick N. Lack of beta-catenin in early life induces abnormal glucose homeostasis in mice. Diabetologia 2009; 52:1608 - 17; http://dx.doi.org/10.1007/s00125-009-1411-y; PMID: 19513688
  • Murtaugh LC, Law AC, Dor Y, Melton DA. Beta-catenin is essential for pancreatic acinar but not islet development. Development 2005; 132:4663 - 74; http://dx.doi.org/10.1242/dev.02063; PMID: 16192304
  • Rulifson IC, Karnik SK, Heiser PW, ten Berge D, Chen H, Gu X, Taketo MM, Nusse R, Hebrok M, Kim SK. Wnt signaling regulates pancreatic beta cell proliferation. Proc Natl Acad Sci U S A 2007; 104:6247 - 52; http://dx.doi.org/10.1073/pnas.0701509104; PMID: 17404238
  • Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R. Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 2001; 128:1253 - 64; PMID: 11262227
  • Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol 1998; 8:1323 - 6; http://dx.doi.org/10.1016/S0960-9822(07)00562-3; PMID: 9843687
  • Ahrens MJ, Romereim S, Dudley AT. A re-evaluation of two key reagents for in vivo studies of Wnt signaling. Dev Dyn 2011; 240:2060 - 8; http://dx.doi.org/10.1002/dvdy.22704; PMID: 21793100
  • Peng S, Zhu Y, Lü B, Xu F, Li X, Lai M. TCF7L2 gene polymorphisms and type 2 diabetes risk: a comprehensive and updated meta-analysis involving 121,174 subjects. Mutagenesis 2013; 28:25 - 37; http://dx.doi.org/10.1093/mutage/ges048; PMID: 23188737
  • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999; 21:70 - 1; http://dx.doi.org/10.1038/5007; PMID: 9916792
  • Marshall BA, Tordjman K, Host HH, Ensor NJ, Kwon G, Marshall CA, Coleman T, McDaniel ML, Semenkovich CF. Relative hypoglycemia and hyperinsulinemia in mice with heterozygous lipoprotein lipase (LPL) deficiency. Islet LPL regulates insulin secretion. J Biol Chem 1999; 274:27426 - 32; http://dx.doi.org/10.1074/jbc.274.39.27426; PMID: 10488074
  • Roe MW, Worley JF 3rd, Qian F, Tamarina N, Mittal AA, Dralyuk F, Blair NT, Mertz RJ, Philipson LH, Dukes ID. Characterization of a Ca2+ release-activated nonselective cation current regulating membrane potential and [Ca2+]i oscillations in transgenically derived beta-cells. J Biol Chem 1998; 273:10402 - 10; http://dx.doi.org/10.1074/jbc.273.17.10402; PMID: 9553098
  • Tamarina NA, Kuznetsov A, Rhodes CJ, Bindokas VP, Philipson LH. Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells. Diabetes 2005; 54:3073 - 81; http://dx.doi.org/10.2337/diabetes.54.11.3073; PMID: 16249428