1,122
Views
8
CrossRef citations to date
0
Altmetric
Report

Comparing CDRH3 diversity captured from secondary lymphoid organs for the generation of recombinant human antibodies

, &
Pages 690-698 | Received 23 May 2013, Accepted 28 Jun 2013, Published online: 02 Jul 2013

References

  • McCafferty J, Griffiths AD, Winter G, Chiswell DJ. Phage antibodies: filamentous phage displaying antibody variable domains. Nature 1990; 348:552 - 4; http://dx.doi.org/10.1038/348552a0; PMID: 2247164
  • Mazor Y, Van Blarcom T, Mabry R, Iverson BL, Georgiou G. Isolation of engineered, full-length antibodies from libraries expressed in Escherichia coli. Nat Biotechnol 2007; 25:563 - 5; http://dx.doi.org/10.1038/nbt1296; PMID: 17435747
  • Feldhaus MJ, Siegel RW, Opresko LK, Coleman JR, Feldhaus JMW, Yeung YA, et al. Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library. Nat Biotechnol 2003; 21:163 - 70; http://dx.doi.org/10.1038/nbt785; PMID: 12536217
  • Hanes J, Plückthun A. In vitro selection and evolution of functional proteins by using ribosome display. Proc Natl Acad Sci U S A 1997; 94:4937 - 42; http://dx.doi.org/10.1073/pnas.94.10.4937; PMID: 9144168
  • Thie H, Meyer T, Schirrmann T, Hust M, Dübel S. Phage display derived therapeutic antibodies. Curr Pharm Biotechnol 2008; 9:439 - 46; http://dx.doi.org/10.2174/138920108786786349; PMID: 19075684
  • Marks JD, Hoogenboom HR, Bonnert TP, McCafferty J, Griffiths AD, Winter G. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J Mol Biol 1991; 222:581 - 97; http://dx.doi.org/10.1016/0022-2836(91)90498-U; PMID: 1748994
  • Sheets MD, Amersdorfer P, Finnern R, Sargent P, Lindquist E, Schier R, et al. Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens. Proc Natl Acad Sci U S A 1998; 95:6157 - 62; http://dx.doi.org/10.1073/pnas.95.11.6157; PMID: 9600934
  • Vaughan TJ, Williams AJ, Pritchard K, Osbourn JK, Pope AR, Earnshaw JC, et al. Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nat Biotechnol 1996; 14:309 - 14; http://dx.doi.org/10.1038/nbt0396-309; PMID: 9630891
  • Griffiths AD, Williams SC, Hartley O, Tomlinson IM, Waterhouse P, Crosby WL, et al. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J 1994; 13:3245 - 60; PMID: 8045255
  • Hoogenboom HR, Winter G. By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro. J Mol Biol 1992; 227:381 - 8; http://dx.doi.org/10.1016/0022-2836(92)90894-P; PMID: 1404359
  • Amersdorfer P, Wong C, Chen S, Smith T, Deshpande S, Sheridan R, et al. Molecular characterization of murine humoral immune response to botulinum neurotoxin type A binding domain as assessed by using phage antibody libraries. Infect Immun 1997; 65:3743 - 52; PMID: 9284147
  • Burton DR, Barbas CF 3rd, Persson MA, Koenig S, Chanock RM, Lerner RA. A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals. Proc Natl Acad Sci U S A 1991; 88:10134 - 7; http://dx.doi.org/10.1073/pnas.88.22.10134; PMID: 1719545
  • Pelat T, Thullier P. Non-human primate immune libraries combined with germline humanization: an (almost) new, and powerful approach for the isolation of therapeutic antibodies. MAbs 2009; 1:377 - 81; http://dx.doi.org/10.4161/mabs.1.4.8635; PMID: 20068407
  • Venet S, Ravn U, Buatois V, Gueneau F, Calloud S, Kosco-Vilbois M, et al. Transferring the characteristics of naturally occurring and biased antibody repertoires to human antibody libraries by trapping CDRH3 sequences. PLoS One 2012; 7:e43471 - 43471; http://dx.doi.org/10.1371/journal.pone.0043471; PMID: 22937053
  • Mebius RE, Kraal G. Structure and function of the spleen. Nat Rev Immunol 2005; 5:606 - 16; http://dx.doi.org/10.1038/nri1669; PMID: 16056254
  • Mak TW and Saunders ME. The immune response, basic and clinical principles. Waltham (MA): Elsevier Academic Press; 2006.
  • Köhler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975; 256:495 - 7; http://dx.doi.org/10.1038/256495a0; PMID: 1172191
  • Gretz JE, Norbury CC, Anderson AO, Proudfoot AE, Shaw S. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J Exp Med 2000; 192:1425 - 40; http://dx.doi.org/10.1084/jem.192.10.1425; PMID: 11085745
  • Nolte MA, Beliën JA, Schadee-Eestermans I, Jansen W, Unger WW, van Rooijen N, et al. A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp. J Exp Med 2003; 198:505 - 12; http://dx.doi.org/10.1084/jem.20021801; PMID: 12900524
  • Carey JB, Moffatt-Blue CS, Watson LC, Gavin AL, Feeney AJ. Repertoire-based selection into the marginal zone compartment during B cell development. J Exp Med 2008; 205:2043 - 52; http://dx.doi.org/10.1084/jem.20080559; PMID: 18710933
  • Başalp A, Yücel F. Development of mouse hybridomas by fusion of myeloma cells with lymphocytes derived from spleen, lymph node, and bone marrow. Hybrid Hybridomics 2003; 22:329 - 31; http://dx.doi.org/10.1089/153685903322538863; PMID: 14678651
  • Mirza IH, Wilkin TJ, Cantarini M, Moore K. A comparison of spleen and lymph node cells as fusion partners for the raising of monoclonal antibodies after different routes of immunisation. J Immunol Methods 1987; 105:235 - 43; http://dx.doi.org/10.1016/0022-1759(87)90271-7; PMID: 3320207
  • Zemlin M, Klinger M, Link J, Zemlin C, Bauer K, Engler JA, et al. Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures. J Mol Biol 2003; 334:733 - 49; http://dx.doi.org/10.1016/j.jmb.2003.10.007; PMID: 14636599
  • Amlot PL, Hayes AE. Impaired human antibody response to the thymus-independent antigen, DNP-Ficoll, after splenectomy. Implications for post-splenectomy infections. Lancet 1985; 1:1008 - 11; http://dx.doi.org/10.1016/S0140-6736(85)91613-7; PMID: 2859463
  • Kraal G. Cells in the marginal zone of the spleen. Int Rev Cytol 1992; 132:31 - 74; http://dx.doi.org/10.1016/S0074-7696(08)62453-5; PMID: 1555921
  • Likhite VV. Immunological impairment and susceptibility to infection after splenectomy. JAMA 1976; 236:1376 - 7; http://dx.doi.org/10.1001/jama.1976.03270130038024; PMID: 989094
  • Ravn U, Didelot G, Venet S, Ng KT, Gueneau F, Rousseau F, et al. Deep sequencing of phage display libraries to support antibody discovery. Methods 2013; 60:99 - 110; http://dx.doi.org/10.1016/j.ymeth.2013.03.001; PMID: 23500657

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.