References
- Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv Immunol 2000; 74:181 - 273; PMID: 10605607
- York IA, Brehm MA, Zendzian S, Towne CF, Rock KL. Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A 2006; 103:9202 - 7; http://dx.doi.org/10.1073/pnas.0603095103; PMID: 16754858
- Nagarajan NA, Shastri N. Immune surveillance for ERAAP dysfunction. Mol Immunol 2013; 55:120 - 2; http://dx.doi.org/10.1016/j.molimm.2012.10.006; PMID: 23433779
- Kamphausen E, Kellert C, Abbas T, Akkad N, Tenzer S, Pawelec G, Schild H, van Endert P, Seliger B. Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma. Cancer Immunol Immunother 2010; 59:1273 - 84; http://dx.doi.org/10.1007/s00262-010-0856-7; PMID: 20419298
- Fruci D, Giacomini P, Nicotra MR, Forloni M, Fraioli R, Saveanu L, van Endert P, Natali PG. Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues. J Cell Physiol 2008; 216:742 - 9; http://dx.doi.org/10.1002/jcp.21454; PMID: 18393273
- Cifaldi L, Lo Monaco E, Forloni M, Giorda E, Lorenzi S, Petrini S, Tremante E, Pende D, Locatelli F, Giacomini P, et al. Natural killer cells efficiently reject lymphoma silenced for the endoplasmic reticulum aminopeptidase associated with antigen processing. Cancer Res 2011; 71:1597 - 606; http://dx.doi.org/10.1158/0008-5472.CAN-10-3326; PMID: 21252114
- James E, Bailey I, Sugiyarto G, Elliott T. Induction of protective antitumor immunity through attenuation of ERAAP function. J Immunol 2013; 190:5839 - 46; http://dx.doi.org/10.4049/jimmunol.1300220; PMID: 23610143
- Stratikos E, Stern LJ. Antigenic peptide trimming by ER aminopeptidases--insights from structural studies. Mol Immunol 2013; 55:212 - 9; http://dx.doi.org/10.1016/j.molimm.2013.03.002; PMID: 23545452
- Zervoudi E, Saridakis E, Birtley JR, Seregin SS, Reeves E, Kokkala P, Aldhamen YA, Amalfitano A, Mavridis IM, James E, et al. Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses. Proc Natl Acad Sci U S A 2013; 110:19890 - 5; http://dx.doi.org/10.1073/pnas.1309781110; PMID: 24248368
- Papakyriakou A, Zervoudi E, Theodorakis EA, Saveanu L, Stratikos E, Vourloumis D. Novel selective inhibitors of aminopeptidases that generate antigenic peptides. Bioorg Med Chem Lett 2013; 23:4832 - 6; http://dx.doi.org/10.1016/j.bmcl.2013.07.024; PMID: 23916253