In vitro organogenesis from pluripotent stem cells

References

• 2013 Runners-Up. Dishing up mini-organs. Science 2013; 342:1436 - 7; http://dx.doi.org/10.1126/science.342.6165.1436-a; PMID: 24357288
   PubMed Web of Science ®Google Scholar
• Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282:1145 - 7; http://dx.doi.org/10.1126/science.282.5391.1145; PMID: 9804556
   PubMed Web of Science ®Google Scholar
• Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861 - 72; http://dx.doi.org/10.1016/j.cell.2007.11.019; PMID: 18035408
   PubMed Web of Science ®Google Scholar
• Lancaster MA, Renner M, Martin CA, Wenzel D, Bicknell LS, Hurles ME, Homfray T, Penninger JM, Jackson AP, Knoblich JA. Cerebral organoids model human brain development and microcephaly. Nature 2013; 501:373 - 9; http://dx.doi.org/10.1038/nature12517; PMID: 23995685
   PubMed Web of Science ®Google Scholar
• Sasai Y. Next-generation regenerative medicine: organogenesis from stem cells in 3D culture. Cell Stem Cell 2013; 12:520 - 30; http://dx.doi.org/10.1016/j.stem.2013.04.009; PMID: 23642363
   PubMed Web of Science ®Google Scholar
• Kinney MA, Hookway TA, Wang Y, McDevitt TC. Engineering three-dimensional stem cell morphogenesis for the development of tissue models and scalable regenerative therapeutics. Ann Biomed Eng 2014; 42:352 - 67; http://dx.doi.org/10.1007/s10439-013-0953-9; PMID: 24297495
   PubMed Web of Science ®Google Scholar
• Sasai Y. Cytosystems dynamics in self-organization of tissue architecture. Nature 2013; 493:318 - 26; http://dx.doi.org/10.1038/nature11859; PMID: 23325214
   PubMed Web of Science ®Google Scholar
• Engle SJ, Puppala D. Integrating human pluripotent stem cells into drug development. Cell Stem Cell 2013; 12:669 - 77; http://dx.doi.org/10.1016/j.stem.2013.05.011; PMID: 23746976
   PubMed Web of Science ®Google Scholar
• Liang P, Lan F, Lee AS, Gong T, Sanchez-Freire V, Wang Y, Diecke S, Sallam K, Knowles JW, Wang PJ, et al. Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. Circulation 2013; 127:1677 - 91; http://dx.doi.org/10.1161/CIRCULATIONAHA.113.001883; PMID: 23519760
   PubMed Web of Science ®Google Scholar
• Hynds RE, Giangreco A. Concise review: the relevance of human stem cell-derived organoid models for epithelial translational medicine. Stem Cells 2013; 31:417 - 22; http://dx.doi.org/10.1002/stem.1290; PMID: 23203919
   PubMed Web of Science ®Google Scholar
• Zweigerdt R, Olmer R, Singh H, Haverich A, Martin U. Scalable expansion of human pluripotent stem cells in suspension culture. Nat Protoc 2011; 6:689 - 700; http://dx.doi.org/10.1038/nprot.2011.318; PMID: 21527925
   PubMed Web of Science ®Google Scholar
• Bratt-Leal AM, Carpenedo RL, McDevitt TC. Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation. Biotechnol Prog 2009; 25:43 - 51; http://dx.doi.org/10.1002/btpr.139; PMID: 19198003
   PubMed Web of Science ®Google Scholar
• Ungrin MD, Joshi C, Nica A, Bauwens C, Zandstra PW. Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates. PLoS One 2008; 3:e1565; http://dx.doi.org/10.1371/journal.pone.0001565; PMID: 18270562
   PubMed Web of Science ®Google Scholar
• Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, et al. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature 2008; 453:524 - 8; http://dx.doi.org/10.1038/nature06894; PMID: 18432194
   PubMed Web of Science ®Google Scholar
• Nair R, Ngangan AV, Kemp ML, McDevitt TC. Gene expression signatures of extracellular matrix and growth factors during embryonic stem cell differentiation. PLoS One 2012; 7:e42580; http://dx.doi.org/10.1371/journal.pone.0042580; PMID: 23077480
   PubMedGoogle Scholar
• Postovit LM, Margaryan NV, Seftor EA, Kirschmann DA, Lipavsky A, Wheaton WW, Abbott DE, Seftor RE, Hendrix MJ. Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells. Proc Natl Acad Sci U S A 2008; 105:4329 - 34; http://dx.doi.org/10.1073/pnas.0800467105; PMID: 18334633
   PubMed Web of Science ®Google Scholar
• Sart S, Ma T, Li Y. Extracellular matrices decellularized from embryonic stem cells maintained their structure and signaling specificity. Tissue Eng Part A 2014; 20:54 - 66; http://dx.doi.org/10.1089/ten.tea.2012.0690; PMID: 23848515
   PubMed Web of Science ®Google Scholar
• Goh SK, Olsen P, Banerjee I. Extracellular matrix aggregates from differentiating embryoid bodies as a scaffold to support ESC proliferation and differentiation. PLoS One 2013; 8:e61856; http://dx.doi.org/10.1371/journal.pone.0061856; PMID: 23637919
   PubMedGoogle Scholar
• Sart S, Agathos SN, Li Y. Engineering stem cell fate with biochemical and biomechanical properties of microcarriers. Biotechnol Prog 2013; 29:1354 - 66; http://dx.doi.org/10.1002/btpr.1825; PMID: 24124017
   PubMed Web of Science ®Google Scholar
• Hughes C, Radan L, Chang WY, Stanford WL, Betts DH, Postovit LM, Lajoie GA. Mass spectrometry-based proteomic analysis of the matrix microenvironment in pluripotent stem cell culture. Mol Cell Proteomics 2012; 11:1924 - 36; http://dx.doi.org/10.1074/mcp.M112.020057; PMID: 23023296
   PubMed Web of Science ®Google Scholar
• Nakano T, Ando S, Takata N, Kawada M, Muguruma K, Sekiguchi K, Saito K, Yonemura S, Eiraku M, Sasai Y. Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell 2012; 10:771 - 85; http://dx.doi.org/10.1016/j.stem.2012.05.009; PMID: 22704518
   PubMed Web of Science ®Google Scholar
• Takebe T, Sekine K, Enomura M, Koike H, Kimura M, Ogaeri T, Zhang RR, Ueno Y, Zheng YW, Koike N, et al. Vascularized and functional human liver from an iPSC-derived organ bud transplant. Nature 2013; 499:481 - 4; http://dx.doi.org/10.1038/nature12271; PMID: 23823721
   PubMed Web of Science ®Google Scholar
• Mariani J, Simonini MV, Palejev D, Tomasini L, Coppola G, Szekely AM, Horvath TL, Vaccarino FM. Modeling human cortical development in vitro using induced pluripotent stem cells. Proc Natl Acad Sci U S A 2012; 109:12770 - 5; http://dx.doi.org/10.1073/pnas.1202944109; PMID: 22761314
   PubMed Web of Science ®Google Scholar
• Eiraku M, Watanabe K, Matsuo-Takasaki M, Kawada M, Yonemura S, Matsumura M, Wataya T, Nishiyama A, Muguruma K, Sasai Y. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell 2008; 3:519 - 32; http://dx.doi.org/10.1016/j.stem.2008.09.002; PMID: 18983967
   PubMed Web of Science ®Google Scholar
• Eiraku M, Takata N, Ishibashi H, Kawada M, Sakakura E, Okuda S, Sekiguchi K, Adachi T, Sasai Y. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 2011; 472:51 - 6; http://dx.doi.org/10.1038/nature09941; PMID: 21475194
   PubMed Web of Science ®Google Scholar
• Suga H, Kadoshima T, Minaguchi M, Ohgushi M, Soen M, Nakano T, Takata N, Wataya T, Muguruma K, Miyoshi H, et al. Self-formation of functional adenohypophysis in three-dimensional culture. Nature 2011; 480:57 - 62; http://dx.doi.org/10.1038/nature10637; PMID: 22080957
   PubMed Web of Science ®Google Scholar
• Xu C, Police S, Hassanipour M, Gold JD. Cardiac bodies: a novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells. Stem Cells Dev 2006; 15:631 - 9; http://dx.doi.org/10.1089/scd.2006.15.631; PMID: 17105398
   PubMed Web of Science ®Google Scholar
• Stevens KR, Pabon L, Muskheli V, Murry CE. Scaffold-free human cardiac tissue patch created from embryonic stem cells. Tissue Eng Part A 2009; 15:1211 - 22; http://dx.doi.org/10.1089/ten.tea.2008.0151; PMID: 19063661
   PubMed Web of Science ®Google Scholar
• Nunes SS, Miklas JW, Liu J, Aschar-Sobbi R, Xiao Y, Zhang B, Jiang J, Massé S, Gagliardi M, Hsieh A, et al. Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes. Nat Methods 2013; 10:781 - 7; http://dx.doi.org/10.1038/nmeth.2524; PMID: 23793239
   PubMed Web of Science ®Google Scholar
• Kim C, Wong J, Wen J, Wang S, Wang C, Spiering S, Kan NG, Forcales S, Puri PL, Leone TC, et al. Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs. Nature 2013; 494:105 - 10; http://dx.doi.org/10.1038/nature11799; PMID: 23354045
   PubMed Web of Science ®Google Scholar
• Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, et al. Design and formulation of functional pluripotent stem cell-derived cardiac microtissues. Proc Natl Acad Sci U S A 2013; 110:E4698 - 707; http://dx.doi.org/10.1073/pnas.1311120110; PMID: 24255110
   PubMed Web of Science ®Google Scholar
• Zhang D, Shadrin IY, Lam J, Xian HQ, Snodgrass HR, Bursac N. Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. Biomaterials 2013; 34:5813 - 20; http://dx.doi.org/10.1016/j.biomaterials.2013.04.026; PMID: 23642535
   PubMed Web of Science ®Google Scholar
• Sart S, Tsai A-C, Li Y, Ma T. Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications. Tissue Eng Part B Rev 2013; In press http://dx.doi.org/10.1089/ten.teb.2013.0537; PMID: 24168395
   PubMed Web of Science ®Google Scholar
• Mummery CL, Zhang J, Ng ES, Elliott DA, Elefanty AG, Kamp TJ. Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview. Circ Res 2012; 111:344 - 58; http://dx.doi.org/10.1161/CIRCRESAHA.110.227512; PMID: 22821908
   PubMed Web of Science ®Google Scholar
• Spence JR, Mayhew CN, Rankin SA, Kuhar MF, Vallance JE, Tolle K, Hoskins EE, Kalinichenko VV, Wells SI, Zorn AM, et al. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature 2011; 470:105 - 9; http://dx.doi.org/10.1038/nature09691; PMID: 21151107
   PubMed Web of Science ®Google Scholar
• Antonica F, Kasprzyk DF, Opitz R, Iacovino M, Liao XH, Dumitrescu AM, Refetoff S, Peremans K, Manto M, Kyba M, et al. Generation of functional thyroid from embryonic stem cells. Nature 2012; 491:66 - 71; http://dx.doi.org/10.1038/nature11525; PMID: 23051751
   PubMed Web of Science ®Google Scholar
• Sneddon JB, Borowiak M, Melton DA. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature 2012; 491:765 - 8; PMID: 23041930
   PubMed Web of Science ®Google Scholar
• Saito H, Takeuchi M, Chida K, Miyajima A. Generation of glucose-responsive functional islets with a three-dimensional structure from mouse fetal pancreatic cells and iPS cells in vitro. PLoS One 2011; 6:e28209; http://dx.doi.org/10.1371/journal.pone.0028209; PMID: 22145030
   PubMedGoogle Scholar
• Wang X, Ye K. Three-dimensional differentiation of embryonic stem cells into islet-like insulin-producing clusters. Tissue Eng Part A 2009; 15:1941 - 52; http://dx.doi.org/10.1089/ten.tea.2008.0181; PMID: 19196138
   PubMed Web of Science ®Google Scholar
• Woodford C, Zandstra PW. Tissue engineering 2.0: guiding self-organization during pluripotent stem cell differentiation. Curr Opin Biotechnol 2012; 23:810 - 9; http://dx.doi.org/10.1016/j.copbio.2012.03.003; PMID: 22444525
   PubMed Web of Science ®Google Scholar
• Kondo S, Miura T. Reaction-diffusion model as a framework for understanding biological pattern formation. Science 2010; 329:1616 - 20; http://dx.doi.org/10.1126/science.1179047; PMID: 20929839
   PubMed Web of Science ®Google Scholar
• Eiraku M, Adachi T, Sasai Y. Relaxation-expansion model for self-driven retinal morphogenesis: a hypothesis from the perspective of biosystems dynamics at the multi-cellular level. Bioessays 2012; 34:17 - 25; http://dx.doi.org/10.1002/bies.201100070; PMID: 22052700
   PubMed Web of Science ®Google Scholar
• Hisha H, Tanaka T, Kanno S, Tokuyama Y, Komai Y, Ohe S, Yanai H, Omachi T, Ueno H. Establishment of a novel lingual organoid culture system: generation of organoids having mature keratinized epithelium from adult epithelial stem cells. Sci Rep 2013; 3:3224; http://dx.doi.org/10.1038/srep03224; PMID: 24232854
   PubMed Web of Science ®Google Scholar
• Sato T, Stange DE, Ferrante M, Vries RG, Van Es JH, Van den Brink S, Van Houdt WJ, Pronk A, Van Gorp J, Siersema PD, et al. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett’s epithelium. Gastroenterology 2011; 141:1762 - 72; http://dx.doi.org/10.1053/j.gastro.2011.07.050; PMID: 21889923
   PubMed Web of Science ®Google Scholar
• Van Winkle AP, Gates ID, Kallos MS. Mass transfer limitations in embryoid bodies during human embryonic stem cell differentiation. Cells Tissues Organs 2012; 196:34 - 47; http://dx.doi.org/10.1159/000330691; PMID: 22249133
   PubMed Web of Science ®Google Scholar
• Sart S, Agathos SN, Li Y. Process engineering of stem cell metabolism for large scale expansion and differentiation in bioreactors. Biochem Eng J 2014; 84:74 - 82; http://dx.doi.org/10.1016/j.bej.2014.01.005
   Web of Science ®Google Scholar
• Kinney MA, Sargent CY, McDevitt TC. The multiparametric effects of hydrodynamic environments on stem cell culture. Tissue Eng Part B Rev 2011; 17:249 - 62; http://dx.doi.org/10.1089/ten.teb.2011.0040; PMID: 21491967
   PubMed Web of Science ®Google Scholar
• Luni C, Serena E, Elvassore N. Human-on-chip for therapy development and fundamental science. Curr Opin Biotechnol 2014; 25:45 - 50; http://dx.doi.org/10.1016/j.copbio.2013.08.015; PMID: 24484880
   PubMed Web of Science ®Google Scholar