2,896
Views
95
CrossRef citations to date
0
Altmetric
Review

Vitamin D, vitamin D receptor and tissue barriers

, &
Article: e23118 | Received 19 Oct 2012, Accepted 04 Dec 2012, Published online: 01 Jan 2013

References

  • Demay MB. Mechanism of vitamin D receptor action. Ann N Y Acad Sci 2006; 1068:204 - 13; http://dx.doi.org/10.1196/annals.1346.026; PMID: 16831920
  • Haussler MR, Whitfield GK, Haussler CA, Hsieh J-C, Thompson PD, Selznick SH, et al. The nuclear vitamin D receptor: biological and molecular regulatory properties revealed. J Bone Miner Res 1998; 13:325 - 49; http://dx.doi.org/10.1359/jbmr.1998.13.3.325; PMID: 9525333
  • Wang Y, Becklund BR, DeLuca HF. Identification of a highly specific and versatile vitamin D receptor antibody. Arch Biochem Biophys 2010; 494:166 - 77; http://dx.doi.org/10.1016/j.abb.2009.11.029; PMID: 19951695
  • Bouillon R, Carmeliet G, Verlinden L, van Etten E, Verstuyf A, Luderer HF, et al. Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev 2008; 29:726 - 76; http://dx.doi.org/10.1210/er.2008-0004; PMID: 18694980
  • Carlberg C, Seuter S. A genomic perspective on vitamin D signaling. Anticancer Res 2009; 29:3485 - 93; PMID: 19667142
  • Bikle DD. Vitamin D and the skin: Physiology and pathophysiology. Rev Endocr Metab Disord 2012; 13:3 - 19; http://dx.doi.org/10.1007/s11154-011-9194-0; PMID: 21845365
  • Deeb KK, Trump DL, Johnson CS. Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nat Rev Cancer 2007; 7:684 - 700; http://dx.doi.org/10.1038/nrc2196; PMID: 17721433
  • Blaney GP, Albert PJ, Proal AD. Vitamin D metabolites as clinical markers in autoimmune and chronic disease. Ann N Y Acad Sci 2009; 1173:384 - 90; http://dx.doi.org/10.1111/j.1749-6632.2009.04875.x; PMID: 19758177
  • Adorini L, Penna G. Control of autoimmune diseases by the vitamin D endocrine system. Nat Clin Pract Rheumatol 2008; 4:404 - 12; http://dx.doi.org/10.1038/ncprheum0855; PMID: 18594491
  • Grau MV, Baron JA, Sandler RS, Haile RW, Beach ML, Church TR, et al. Vitamin D, calcium supplementation and colorectal adenomas: results of a randomized trial. J Natl Cancer Inst 2003; 95:1765 - 71; http://dx.doi.org/10.1093/jnci/djg110; PMID: 14652238
  • Gocek E, Studzinski GP. Vitamin D and differentiation in cancer. Crit Rev Clin Lab Sci 2009; 46:190 - 209; http://dx.doi.org/10.1080/10408360902982128; PMID: 19650715
  • Heaney RP. Vitamin D in health and disease. Clin J Am Soc Nephrol 2008; 3:1535 - 41; http://dx.doi.org/10.2215/CJN.01160308; PMID: 18525006
  • Cannell JJ, Hollis BW, Zasloff M, Heaney RP. Diagnosis and treatment of vitamin D deficiency. Expert Opin Pharmacother 2008; 9:107 - 18; http://dx.doi.org/10.1517/14656566.9.1.107; PMID: 18076342
  • Campbell FC, Xu H, El-Tanani M, Crowe P, Bingham V. The yin and yang of vitamin D receptor (VDR) signaling in neoplastic progression: operational networks and tissue-specific growth control. Biochem Pharmacol 2010; 79:1 - 9; http://dx.doi.org/10.1016/j.bcp.2009.09.005; PMID: 19737544
  • Katoh M, Katoh M. WNT signaling pathway and stem cell signaling network. Clin Cancer Res 2007; 13:4042 - 5; http://dx.doi.org/10.1158/1078-0432.CCR-06-2316; PMID: 17634527
  • Terzić J, Grivennikov S, Karin E, Karin M. Inflammation and colon cancer. Gastroenterology 2010; 138:2101 - 14.e5; http://dx.doi.org/10.1053/j.gastro.2010.01.058; PMID: 20420949
  • Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997; 275:1787 - 90; http://dx.doi.org/10.1126/science.275.5307.1787; PMID: 9065402
  • Shah S, Islam MN, Dakshanamurthy S, Rizvi I, Rao M, Herrell R, et al. The molecular basis of vitamin D receptor and beta-catenin crossregulation. Mol Cell 2006; 21:799 - 809; http://dx.doi.org/10.1016/j.molcel.2006.01.037; PMID: 16543149
  • Haussler MR, Haussler CA, Whitfield GK, Hsieh JC, Thompson PD, Barthel TK, et al. The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the “Fountain of Youth” to mediate healthful aging. J Steroid Biochem Mol Biol 2010; 121:88 - 97; http://dx.doi.org/10.1016/j.jsbmb.2010.03.019; PMID: 20227497
  • Pendás-Franco N, Aguilera O, Pereira F, González-Sancho JM, Muñoz A. Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes. Anticancer Res 2008; 28:5A 2613 - 23; PMID: 19035286
  • Larriba MJ, Valle N, Pálmer HG, Ordóñez-Morán P, Alvarez-Díaz S, Becker KF, et al. The inhibition of Wnt/beta-catenin signalling by 1alpha,25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells. Endocr Relat Cancer 2007; 14:141 - 51; http://dx.doi.org/10.1677/ERC-06-0028; PMID: 17395983
  • Pálmer HG, González-Sancho JM, Espada J, Berciano MT, Puig I, Baulida J, et al. Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J Cell Biol 2001; 154:369 - 87; http://dx.doi.org/10.1083/jcb.200102028; PMID: 11470825
  • Furuse M. Molecular basis of the core structure of tight junctions. Cold Spring Harb Perspect Biol 2010; 2:a002907; http://dx.doi.org/10.1101/cshperspect.a002907; PMID: 20182608
  • Migliori M, Giovannini L, Panichi V, Filippi C, Taccola D, Origlia N, et al. Treatment with 1,25-dihydroxyvitamin D3 preserves glomerular slit diaphragm-associated protein expression in experimental glomerulonephritis. Int J Immunopathol Pharmacol 2005; 18:779 - 90; PMID: 16388728
  • Yin Z, Pintea V, Lin Y, Hammock BD, Watsky MA. Vitamin D enhances corneal epithelial barrier function. Invest Ophthalmol Vis Sci 2011; 52:7359 - 64; http://dx.doi.org/10.1167/iovs.11-7605; PMID: 21715350
  • Fujita H, Sugimoto K, Inatomi S, Maeda T, Osanai M, Uchiyama Y, et al. Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Mol Biol Cell 2008; 19:1912 - 21; http://dx.doi.org/10.1091/mbc.E07-09-0973; PMID: 18287530
  • Kong J, Zhang Z, Musch MW, Ning G, Sun J, Hart J, et al. Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier. Am J Physiol Gastrointest Liver Physiol 2008; 294:G208 - 16; http://dx.doi.org/10.1152/ajpgi.00398.2007; PMID: 17962355
  • Zeissig S, Bürgel N, Günzel D, Richter J, Mankertz J, Wahnschaffe U, et al. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease. Gut 2007; 56:61 - 72; http://dx.doi.org/10.1136/gut.2006.094375; PMID: 16822808
  • Rosenthal R, Milatz S, Krug SM, Oelrich B, Schulzke JD, Amasheh S, et al. Claudin-2, a component of the tight junction, forms a paracellular water channel. J Cell Sci 2010; 123:1913 - 21; http://dx.doi.org/10.1242/jcs.060665; PMID: 20460438
  • Schulzke JD, Fromm M. Tight junctions: molecular structure meets function. Ann N Y Acad Sci 2009; 1165:1 - 6; http://dx.doi.org/10.1111/j.1749-6632.2009.04925.x; PMID: 19538280
  • Van Itallie CM, Holmes J, Bridges A, Anderson JM. Claudin-2-dependent changes in noncharged solute flux are mediated by the extracellular domains and require attachment to the PDZ-scaffold. Ann N Y Acad Sci 2009; 1165:82 - 7; http://dx.doi.org/10.1111/j.1749-6632.2009.04052.x; PMID: 19538292
  • Holmes JL, Van Itallie CM, Rasmussen JE, Anderson JM. Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns. Gene Expr Patterns 2006; 6:581 - 8; http://dx.doi.org/10.1016/j.modgep.2005.12.001; PMID: 16458081
  • Christakos S, Dhawan P, Ajibade D, Benn BS, Feng J, Joshi SS. Mechanisms involved in vitamin D mediated intestinal calcium absorption and in non-classical actions of vitamin D. J Steroid Biochem Mol Biol 2010; 121:183 - 7; http://dx.doi.org/10.1016/j.jsbmb.2010.03.005; PMID: 20214989
  • Hartmann B, Riedel R, Jörss K, Loddenkemper C, Steinmeyer A, Zügel U, et al. Vitamin D receptor activation improves allergen-triggered eczema in mice. J Invest Dermatol 2012; 132:330 - 6; http://dx.doi.org/10.1038/jid.2011.296; PMID: 21938012
  • Hollander D. Crohn’s disease--a permeability disorder of the tight junction?. Gut 1988; 29:1621 - 4; http://dx.doi.org/10.1136/gut.29.12.1621; PMID: 3065154
  • Schulzke JD, Ploeger S, Amasheh M, Fromm A, Zeissig S, Troeger H, et al. Epithelial tight junctions in intestinal inflammation. Ann N Y Acad Sci 2009; 1165:294 - 300; http://dx.doi.org/10.1111/j.1749-6632.2009.04062.x; PMID: 19538319
  • Ivanov AI, Nusrat A, Parkos CA. The epithelium in inflammatory bowel disease: potential role of endocytosis of junctional proteins in barrier disruption. Novartis Found Symp 2004; 263:115 - 24, discussion 124-32, 211-8; http://dx.doi.org/10.1002/0470090480.ch9; PMID: 15669638
  • Weber CR, Nalle SC, Tretiakova M, Rubin DT, Turner JR. Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation. Lab Invest 2008; 88:1110 - 20; http://dx.doi.org/10.1038/labinvest.2008.78; PMID: 18711353
  • Arnott ID, Kingstone K, Ghosh S. Abnormal intestinal permeability predicts relapse in inactive Crohn disease. Scand J Gastroenterol 2000; 35:1163 - 9; http://dx.doi.org/10.1080/003655200750056637; PMID: 11145287
  • Wyatt J, Vogelsang H, Hübl W, Waldhöer T, Lochs H. Intestinal permeability and the prediction of relapse in Crohn’s disease. Lancet 1993; 341:1437 - 9; http://dx.doi.org/10.1016/0140-6736(93)90882-H; PMID: 8099141
  • Laukoetter MG, Nava P, Lee WY, Severson EA, Capaldo CT, Babbin BA, et al. JAM-A regulates permeability and inflammation in the intestine in vivo. J Exp Med 2007; 204:3067 - 76; http://dx.doi.org/10.1084/jem.20071416; PMID: 18039951
  • Zhao H, Zhang H, Wu H, Li H, Liu L, Guo J, et al. Protective role of 1,25(OH)2 vitamin D3 in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice. BMC Gastroenterol 2012; 12:57; http://dx.doi.org/10.1186/1471-230X-12-57; PMID: 22647055
  • Wu S, Liao AP, Xia Y, Li YC, Li JD, Sartor RB, et al. Vitamin D receptor negatively regulates bacterial-stimulated NF-kappaB activity in intestine. Am J Pathol 2010; 177:686 - 97; http://dx.doi.org/10.2353/ajpath.2010.090998; PMID: 20566739
  • Sun J. Vitamin D and mucosal immune function. Curr Opin Gastroenterol 2010; 26:591 - 5; http://dx.doi.org/10.1097/MOG.0b013e32833d4b9f; PMID: 20639756
  • Agrawal T, Gupta GK, Agrawal DK. Vitamin D deficiency decreases the expression of VDR and prohibitin in the lungs of mice with allergic airway inflammation. Exp Mol Pathol 2012; 93:74 - 81; http://dx.doi.org/10.1016/j.yexmp.2012.04.004; PMID: 22537547
  • Finklea JD, Grossmann RE, Tangpricha V. Vitamin D and chronic lung disease: a review of molecular mechanisms and clinical studies. Adv Nutr 2011; 2:244 - 53; http://dx.doi.org/10.3945/an.111.000398; PMID: 22332056
  • Mak G, Hanania NA. Vitamin D and asthma. Curr Opin Pulm Med 2011; 17:1 - 5; http://dx.doi.org/10.1097/MCP.0b013e3283411440; PMID: 21045696
  • Zosky GR, Berry LJ, Elliot JG, James AL, Gorman S, Hart PH. Vitamin D deficiency causes deficits in lung function and alters lung structure. Am J Respir Crit Care Med 2011; 183:1336 - 43; http://dx.doi.org/10.1164/rccm.201010-1596OC; PMID: 21297070
  • Finklea JD, Grossmann RE, Tangpricha V. Vitamin D and chronic lung disease: a review of molecular mechanisms and clinical studies. Adv Nutr 2011; 2:244 - 53; http://dx.doi.org/10.3945/an.111.000398; PMID: 22332056
  • Sundar IK, Hwang JW, Wu S, Sun J, Rahman I. Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation. Biochem Biophys Res Commun 2011; 406:127 - 33; http://dx.doi.org/10.1016/j.bbrc.2011.02.011; PMID: 21300024
  • Laverny G, Penna G, Vetrano S, Correale C, Nebuloni M, Danese S, et al. Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease. Immunol Lett 2010; 131:49 - 58; http://dx.doi.org/10.1016/j.imlet.2010.03.006; PMID: 20350569
  • Goff JP, Koszewski NJ, Haynes JS, Horst RL. Targeted delivery of vitamin D to the colon using β-glucuronides of vitamin D: therapeutic effects in a murine model of inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol 2012; 302:G460 - 9; http://dx.doi.org/10.1152/ajpgi.00156.2011; PMID: 22114117
  • Miheller P, Muzes G, Hritz I, Lakatos G, Pregun I, Lakatos PL, et al. Comparison of the effects of 1,25 dihydroxyvitamin D and 25 hydroxyvitamin D on bone pathology and disease activity in Crohn’s disease patients. Inflamm Bowel Dis 2009; 15:1656 - 62; http://dx.doi.org/10.1002/ibd.20947; PMID: 19408329
  • Valdivielso JM, Cannata-Andía J, Coll B, Fernández E. A new role for vitamin D receptor activation in chronic kidney disease. Am J Physiol Renal Physiol 2009; 297:F1502 - 9; http://dx.doi.org/10.1152/ajprenal.00130.2009; PMID: 19625376
  • Naves-Díaz M, Alvarez-Hernández D, Passlick-Deetjen J, Guinsburg A, Marelli C, Rodriguez-Puyol D, et al. Oral active vitamin D is associated with improved survival in hemodialysis patients. Kidney Int 2008; 74:1070 - 8; http://dx.doi.org/10.1038/ki.2008.343; PMID: 18633342
  • Teng M, Wolf M, Ofsthun MN, Lazarus JM, Hernán MA, Camargo CA Jr., et al. Activated injectable vitamin D and hemodialysis survival: a historical cohort study. J Am Soc Nephrol 2005; 16:1115 - 25; http://dx.doi.org/10.1681/ASN.2004070573; PMID: 15728786
  • Dombrowski Y, Peric M, Koglin S, Ruzicka T, Schauber J. Control of cutaneous antimicrobial peptides by vitamin D3. Arch Dermatol Res 2010; 302:401 - 8; http://dx.doi.org/10.1007/s00403-010-1045-4; PMID: 20221619
  • Gombart AF, Borregaard N, Koeffler HP. Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3. FASEB J 2005; 19:1067 - 77; http://dx.doi.org/10.1096/fj.04-3284com; PMID: 15985530
  • Muehleisen B, Bikle DD, Aguilera C, Burton DW, Sen GL, Deftos LJ, et al. PTH/PTHrP and vitamin D control antimicrobial peptide expression and susceptibility to bacterial skin infection. Sci Transl Med 2012; 4:35ra66; http://dx.doi.org/10.1126/scitranslmed.3003759; PMID: 22623742
  • Hata TR, Kotol P, Jackson M, Nguyen M, Paik A, Udall D, et al. Administration of oral vitamin D induces cathelicidin production in atopic individuals. J Allergy Clin Immunol 2008; 122:829 - 31; http://dx.doi.org/10.1016/j.jaci.2008.08.020; PMID: 19014773
  • Heilborn JD, Weber G, Grönberg A, Dieterich C, Ståhle M. Topical treatment with the vitamin D analogue calcipotriol enhances the upregulation of the antimicrobial protein hCAP18/LL-37 during wounding in human skin in vivo. Exp Dermatol 2010; 19:332 - 8; http://dx.doi.org/10.1111/j.1600-0625.2009.00997.x; PMID: 19878298
  • Peric M, Koglin S, Dombrowski Y, Gross K, Bradac E, Büchau A, et al. Vitamin D analogs differentially control antimicrobial peptide/”alarmin” expression in psoriasis. PLoS One 2009; 4:e6340; http://dx.doi.org/10.1371/journal.pone.0006340; PMID: 19623255
  • Ma JX, Xia JB, Cheng XM, Wang CZ. 1,25-dihydroxyvitamin D₃ pretreatment enhances the efficacy of allergen immunotherapy in a mouse allergic asthma model. Chin Med J (Engl) 2010; 123:3591 - 6; PMID: 22166637
  • Martineau AR, Timms PM, Bothamley GH, Hanifa Y, Islam K, Claxton AP, et al. High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial. Lancet 2011; 377:242 - 50; http://dx.doi.org/10.1016/S0140-6736(10)61889-2; PMID: 21215445
  • Slominski AT, Kim TK, Janjetovic Z, Tuckey RC, Bieniek R, Yue J, et al. 20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells. Am J Physiol Cell Physiol 2011; 300:C526 - 41; http://dx.doi.org/10.1152/ajpcell.00203.2010; PMID: 21160030
  • Slominski AT, Kim TK, Chen J, Nguyen MN, Li W, Yates CR, et al. Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes. Int J Biochem Cell Biol 2012; 44:2003 - 18; http://dx.doi.org/10.1016/j.biocel.2012.07.027; PMID: 22877869
  • Slominski AT, Kim TK, Shehabi HZ, Semak I, Tang EK, Nguyen MN, et al. In vivo evidence for a novel pathway of vitamin D₃ metabolism initiated by P450scc and modified by CYP27B1. FASEB J 2012; 26:3901 - 15; http://dx.doi.org/10.1096/fj.12-208975; PMID: 22683847
  • Ordóñez-Morán P, Alvarez-Díaz S, Valle N, Larriba MJ, Bonilla F, Muñoz A. The effects of 1,25-dihydroxyvitamin D3 on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling. J Steroid Biochem Mol Biol 2010; 121:355 - 61; http://dx.doi.org/10.1016/j.jsbmb.2010.02.031; PMID: 20223287
  • Haussler MR, Whitfield GK, Kaneko I, Haussler CA, Hsieh D, Hsieh JC, et al. Molecular Mechanisms of Vitamin D Action. Calcif Tissue Int 2012; http://dx.doi.org/10.1007/s00223-012-9619-0; PMID: 22782502
  • Pereira F, Barbáchano A, Silva J, Bonilla F, Campbell MJ, Muñoz A, et al. KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells. Hum Mol Genet 2011; 20:4655 - 65; http://dx.doi.org/10.1093/hmg/ddr399; PMID: 21890490