Characterization of a 5-azacytidine-induced developmental Aspergillus fumigatus variant

References

• Tamame M, Antequera F, Santos E. Developmental characterization and chromosomal mapping of the 5-azacytidine-sensitive fluF locus of Aspergillus nidulans. Mol Cell Biol 1988; 8:3043 - 3050
   PubMed Web of Science ®Google Scholar
• Tamame M, Antequera F, Villanueva JR, Santos T. High-frequency conversion to a “fluffy” developmental phenotype in Aspergillus spp. by 5-azacytidine treatment: evidence for involvement of a single nuclear gene. Mol Cell Biol 1983; 3:2287 - 2297
   PubMed Web of Science ®Google Scholar
• Segal BH. Aspergillosis. N Engl J Med 2009; 360:1870 - 1884
   PubMed Web of Science ®Google Scholar
• Garcia-Manero G. Demethylating agents in myeloid malignancies. Curr Opin Oncol 2008; 20:705 - 710
   PubMed Web of Science ®Google Scholar
• Paris S, Wysong D, Debeaupuis JP, et al. Catalases of Aspergillus fumigatus. Infect Immun 2003; 71:3551 - 3562
   PubMed Web of Science ®Google Scholar
• Eisendle M, Schrettl M, Kragl C, Muller D, Illmer P, Haas H. The intracellular siderophore ferricrocin is involved in iron storage, oxidative-stress resistance, germination and sexual development in Aspergillus nidulans. Eukaryot Cell 2006; 5:1596 - 1603
   PubMed Web of Science ®Google Scholar
• Clinical and Laboratory Standards Institute. Reference method for broth dilution antifungal susceptibility testing of filamentous fungi Approved standard M38-A2 2008; Wayne, PA Clinical and Laboratory Standards Institute
   Google Scholar
• Lionakis MS, Lewis RE, May GS, et al. Toll-deficient Drosophila flies as a fast, high-throughput model for the study of antifungal drug efficacy against invasive aspergillosis and Aspergillus virulence. J Infect Dis 2005; 191:1188 - 1195
   PubMed Web of Science ®Google Scholar
• Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996; 86:973 - 983
   PubMed Web of Science ®Google Scholar
• Bowman JC, Abruzzo GK, Anderson JW, et al. Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate. Antimicrob Agents Chemother 2001; 45:3474 - 3481
   PubMed Web of Science ®Google Scholar
• Blanco JL, Hontecillas R, Bouza E, et al. Correlation between the elastase activity index and invasiveness of clinical isolates of Aspergillus fumigatus. J Clin Microbiol 2002; 40:1811 - 1813
   PubMed Web of Science ®Google Scholar
• Kothary MH, Chase T Jr, Macmillan JD. Correlation of elastase production by some strains of Aspergillus fumigatus with ability to cause pulmonary invasive aspergillosis in mice. Infect Immun 1984; 43:320 - 325
   PubMed Web of Science ®Google Scholar
• Nierman WC, Pain A, Anderson MJ, et al. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature 2005; 438:1151 - 1156
   PubMed Web of Science ®Google Scholar
• Saeed AI, Sharov V, White J, et al. TM4: a free, open-source system for microarray data management and analysis. Biotechniques 2003; 34:374 - 378
   PubMed Web of Science ®Google Scholar
• Saeed AI, Bhagabati NK, Braisted JC, et al. TM4 microarray software suite. Methods Enzymol 2006; 411:134 - 193
   PubMed Web of Science ®Google Scholar
• Yu JH, Mah JH, Seo JA. Growth and developmental control in the model and pathogenic aspergilli. Eukaryot Cell 2006; 5:1577 - 1584
   PubMed Web of Science ®Google Scholar
• Lee BN, Adams TH. The Aspergillus nidulans fluG gene is required for production of an extracellular developmental signal and is related to prokaryotic glutamine synthetase I. Genes Dev 1994; 8:641 - 651
   PubMed Web of Science ®Google Scholar
• Dutton JR, Johns S, Miller BL. StuAp is a sequence-specific transcription factor that regulates developmental complexity in Aspergillus nidulans. EMBO J 1997; 16:5710 - 5721
   PubMed Web of Science ®Google Scholar
• Chow CM, RajBhandary UL. Developmental regulation of the gene for formate dehydrogenase in Neurospora crassa. J Bacteriol 1993; 175:3703 - 3709
   PubMed Web of Science ®Google Scholar
• Lee JD, Kolattukudy PE. Molecular cloning of the cDNA and gene for an elastinolytic aspartic proteinase from Aspergillus fumigatus and evidence of its secretion by the fungus during invasion of the host lung. Infect Immun 1995; 63:3796 - 3803
   PubMed Web of Science ®Google Scholar
• Li L, Wright SJ, Krystofova S, Park G, Borkovich KA. Heterotrimeric G protein signaling in filamentous fungi. Annu Rev Microbiol 2007; 61:423 - 452
   PubMed Web of Science ®Google Scholar
• Lee BN, Adams TH. Overexpression of flbA, an early regulator of Aspergillus asexual sporulation, leads to activation of brlA and premature initiation of development. Mol Microbiol 1994; 14:323 - 334
   PubMed Web of Science ®Google Scholar
• Rosen S, Yu JH, Adams TH. The Aspergillus nidulans sfaD gene encodes a G protein beta subunit that is required for normal growth and repression of sporulation. EMBO J 1999; 18:5592 - 5600
   PubMed Web of Science ®Google Scholar
• Yu JH, Wieser J, Adams TH. The Aspergillus FlbA RGS domain protein antagonizes G protein signaling to block proliferation and allow development. EMBO J 1996; 15:5184 - 5190
   PubMed Web of Science ®Google Scholar
• Spudich JL, Yang CS, Jung KH, Spudich EN. Retinylidene proteins: structures and functions from archaea to humans. Annu Rev Cell Dev Biol 2000; 16:365 - 392
   PubMed Web of Science ®Google Scholar
• Gurevich EV, Gurevich VV. Arrestins: ubiquitous regulators of cellular signaling pathways. Genome Biol 2006; 7:236
   PubMed Web of Science ®Google Scholar
• Bergmann A, Hartmann T, Cairns T, Bignell EM, Krappmann S. A regulator of Aspergillus fumigatus extracellular proteolytic activity is dispensable for virulence. Infect Immun 2009; 77:4041 - 4050
   PubMed Web of Science ®Google Scholar
• Sharon H, Hagag S, Osherov N. Transcription factor PrtT controls expression of multiple secreted proteases in the human pathogenic mold Aspergillus fumigatus. Infect Immun 2009; 77:4051 - 4060
   PubMed Web of Science ®Google Scholar
• Moutaouakil M, Monod M, Prevost MC, Bouchara JP, Paris S, Latge JP. Identification of the 33-kDa alkaline protease of Aspergillus fumigatus in vitro and in vivo. J Med Microbiol 1993; 39:393 - 399
   PubMed Web of Science ®Google Scholar
• Pharmion Corporation. Azacitidine Investigator's Brochure 2007; 5th ed. Boulder, CO
   Google Scholar
• Kumpatla SP, Teng W, Buchholz WG, Hall TC. Epigenetic transcriptional silencing and 5-azacytidine-mediated reactivation of a complex transgene in rice. Plant Physiol 1997; 115:361 - 373
   PubMed Web of Science ®Google Scholar
• Garcia-Manero G, Stoltz ML, Ward MR, Kantarjian H, Sharma S. A pilot pharmacokinetic study of oral azacitidine. Leukemia 2008; 22:1680 - 1684
   PubMed Web of Science ®Google Scholar