Uncovering cellular circuitry controlling temperature-dependent fungal morphogenesis

References

• Blackwell M. The fungi: 1, 2, 3 ... 5.1 million species?. Am J Bot 2011; 98:426 - 38; http://dx.doi.org/10.3732/ajb.1000298; PMID: 21613136
   PubMed Web of Science ®Google Scholar
• Robert VA, Casadevall A. Vertebrate endothermy restricts most fungi as potential pathogens. J Infect Dis 2009; 200:1623 - 6; http://dx.doi.org/10.1086/644642; PMID: 19827944
   PubMed Web of Science ®Google Scholar
• Klein BS, Tebbets B. Dimorphism and virulence in fungi. Curr Opin Microbiol 2007; 10:314 - 9; http://dx.doi.org/10.1016/j.mib.2007.04.002; PMID: 17719267
   PubMed Web of Science ®Google Scholar
• Calderone R. Candida and Candidiasis. Washington, D.C.: ASM Press, 2002.
   Google Scholar
• Nicholls S, Leach MD, Priest CL, Brown AJ. Role of the heat shock transcription factor, Hsf1, in a major fungal pathogen that is obligately associated with warm-blooded animals. Mol Microbiol 2009; 74:844 - 61; http://dx.doi.org/10.1111/j.1365-2958.2009.06883.x; PMID: 19818013
   PubMed Web of Science ®Google Scholar
• Shapiro RS, Robbins N, Cowen LE. Regulatory circuitry governing fungal development, drug resistance, and disease. Microbiol Mol Biol Rev 2011; 75:213 - 67; http://dx.doi.org/10.1128/MMBR.00045-10; PMID: 21646428
   PubMed Web of Science ®Google Scholar
• Noble SM, French S, Kohn LA, Chen V, Johnson AD. Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity. Nat Genet 2010; 42:590 - 8; http://dx.doi.org/10.1038/ng.605; PMID: 20543849
   PubMed Web of Science ®Google Scholar
• Shapiro RS, Uppuluri P, Zaas AK, Collins C, Senn H, Perfect JR, et al. Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling. Curr Biol 2009; 19:621 - 9; http://dx.doi.org/10.1016/j.cub.2009.03.017; PMID: 19327993
   PubMed Web of Science ®Google Scholar
• Senn H, Shapiro RS, Cowen LE. Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans. Mol Biol Cell 2012; 23:268 - 83; http://dx.doi.org/10.1091/mbc.E11-08-0729; PMID: 22090345
   PubMed Web of Science ®Google Scholar
• Brown DH Jr., Giusani AD, Chen X, Kumamoto CA. Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gene. Mol Microbiol 1999; 34:651 - 62; http://dx.doi.org/10.1046/j.1365-2958.1999.01619.x; PMID: 10564506
   PubMed Web of Science ®Google Scholar
• Pukkila-Worley R, Peleg AY, Tampakakis E, Mylonakis E. Candida albicans hyphal formation and virulence assessed using a Caenorhabditis elegans infection model. Eukaryot Cell 2009; 8:1750 - 8; http://dx.doi.org/10.1128/EC.00163-09; PMID: 19666778
   PubMed Web of Science ®Google Scholar
• Shapiro RS, Sellam A, Tebbji F, Whiteway M, Nantel A, Cowen LE. Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise. Curr Biol 2012; 22:461 - 70; http://dx.doi.org/10.1016/j.cub.2012.01.062; PMID: 22365851
   PubMed Web of Science ®Google Scholar
• Xu XL, Lee RT, Fang HM, Wang YM, Li R, Zou H, et al. Bacterial peptidoglycan triggers Candida albicans hyphal growth by directly activating the adenylyl cyclase Cyr1p. Cell Host Microbe 2008; 4:28 - 39; http://dx.doi.org/10.1016/j.chom.2008.05.014; PMID: 18621008
   PubMed Web of Science ®Google Scholar
• Zhao R, Davey M, Hsu YC, Kaplanek P, Tong A, Parsons AB, et al. Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the Hsp90 chaperone. Cell 2005; 120:715 - 27; http://dx.doi.org/10.1016/j.cell.2004.12.024; PMID: 15766533
   PubMed Web of Science ®Google Scholar
• Diezmann S, Michaut M, Shapiro RS, Bader GD, Cowen LE. Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry. PLoS Genet 2012; 8:e1002562; http://dx.doi.org/10.1371/journal.pgen.1002562; PMID: 22438817
   PubMed Web of Science ®Google Scholar
• Lorenz MC, Heitman J. Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. Genetics 1998; 150:1443 - 57; PMID: 9832522
   PubMed Web of Science ®Google Scholar
• Chua G, Morris QD, Sopko R, Robinson MD, Ryan O, Chan ET, et al. Identifying transcription factor functions and targets by phenotypic activation. Proc Natl Acad Sci U S A 2006; 103:12045 - 50; http://dx.doi.org/10.1073/pnas.0605140103; PMID: 16880382
   PubMed Web of Science ®Google Scholar
• Bussink HJ, Osmani SA. A cyclin-dependent kinase family member (PHOA) is required to link developmental fate to environmental conditions in Aspergillus nidulans. EMBO J 1998; 17:3990 - 4003; http://dx.doi.org/10.1093/emboj/17.14.3990; PMID: 9670015
   PubMed Web of Science ®Google Scholar
• Dou X, Wu D, An W, Davies J, Hashmi SB, Ukil L, et al. The PHOA and PHOB cyclin-dependent kinases perform an essential function in Aspergillus nidulans. Genetics 2003; 165:1105 - 15; PMID: 14668368
   PubMed Web of Science ®Google Scholar
• de Jesús-Berríos M, Rodríguez-del Valle N. Expression of a Pho85 cyclin-dependent kinase is repressed during the dimorphic transition in Sporothrix schenckii. Fungal Genet Biol 2002; 37:39 - 48; http://dx.doi.org/10.1016/S1087-1845(02)00031-2; PMID: 12223188
   PubMed Web of Science ®Google Scholar
• Castillo-Lluva S, Alvarez-Tabarés I, Weber I, Steinberg G, Pérez-Martín J. Sustained cell polarity and virulence in the phytopathogenic fungus Ustilago maydis depends on an essential cyclin-dependent kinase from the Cdk5/Pho85 family. J Cell Sci 2007; 120:1584 - 95; http://dx.doi.org/10.1242/jcs.005314; PMID: 17405809
   PubMed Web of Science ®Google Scholar
• Taipale M, Jarosz DF, Lindquist S. HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat Rev Mol Cell Biol 2010; 11:515 - 28; http://dx.doi.org/10.1038/nrm2918; PMID: 20531426
   PubMed Web of Science ®Google Scholar
• Mandal AK, Lee P, Chen JA, Nillegoda N, Heller A, DiStasio S, et al. Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturation. J Cell Biol 2007; 176:319 - 28; http://dx.doi.org/10.1083/jcb.200604106; PMID: 17242065
   PubMed Web of Science ®Google Scholar
• Kwon-Chung KJ, Polacheck I, Popkin TJ. Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice. J Bacteriol 1982; 150:1414 - 21; PMID: 6804444
   PubMed Web of Science ®Google Scholar
• Liu OW, Chun CD, Chow ED, Chen C, Madhani HD, Noble SM. Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans. Cell 2008; 135:174 - 88; http://dx.doi.org/10.1016/j.cell.2008.07.046; PMID: 18854164
   PubMed Web of Science ®Google Scholar
• Alspaugh JA, Cavallo LM, Perfect JR, Heitman J. RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans. Mol Microbiol 2000; 36:352 - 65; http://dx.doi.org/10.1046/j.1365-2958.2000.01852.x; PMID: 10792722
   PubMed Web of Science ®Google Scholar
• Odom A, Muir S, Lim E, Toffaletti DL, Perfect J, Heitman J. Calcineurin is required for virulence of Cryptococcus neoformans. EMBO J 1997; 16:2576 - 89; http://dx.doi.org/10.1093/emboj/16.10.2576; PMID: 9184205
   PubMed Web of Science ®Google Scholar
• Bhabhra R, Richie DL, Kim HS, Nierman WC, Fortwendel J, Aris JP, et al. Impaired ribosome biogenesis disrupts the integration between morphogenesis and nuclear duplication during the germination of Aspergillus fumigatus. Eukaryot Cell 2008; 7:575 - 83; http://dx.doi.org/10.1128/EC.00412-07; PMID: 18296619
   PubMed Web of Science ®Google Scholar
• McCusker JH, Clemons KV, Stevens DA, Davis RW. Saccharomyces cerevisiae virulence phenotype as determined with CD-1 mice is associated with the ability to grow at 42 degrees C and form pseudohyphae. Infect Immun 1994; 62:5447 - 55; PMID: 7960125
   PubMed Web of Science ®Google Scholar
• Nemecek JC, Wüthrich M, Klein BS. Global control of dimorphism and virulence in fungi. Science 2006; 312:583 - 8; http://dx.doi.org/10.1126/science.1124105; PMID: 16645097
   PubMed Web of Science ®Google Scholar
• Nguyen VQ, Sil A. Temperature-induced switch to the pathogenic yeast form of Histoplasma capsulatum requires Ryp1, a conserved transcriptional regulator. Proc Natl Acad Sci U S A 2008; 105:4880 - 5; http://dx.doi.org/10.1073/pnas.0710448105; PMID: 18339808
   PubMed Web of Science ®Google Scholar
• Rodriguez-Caban J, Gonzalez-Velazquez W, Perez-Sanchez L, Gonzalez-Mendez R, Valle NR. Calcium/calmodulin kinase1 and its relation to thermotolerance and HSP90 in Sporothrix schenckii: an RNAi and yeast two-hybrid study. BMC Microbiol 2011; 11:162; http://dx.doi.org/10.1186/1471-2180-11-162; PMID: 21745372
   PubMed Web of Science ®Google Scholar
• Lohse MB, Johnson AD. White-opaque switching in Candida albicans. Curr Opin Microbiol 2009; 12:650 - 4; http://dx.doi.org/10.1016/j.mib.2009.09.010; PMID: 19853498
   PubMed Web of Science ®Google Scholar
• Lachke SA, Lockhart SR, Daniels KJ, Soll DR. Skin facilitates Candida albicans mating. Infect Immun 2003; 71:4970 - 6; http://dx.doi.org/10.1128/IAI.71.9.4970-4976.2003; PMID: 12933839
   PubMed Web of Science ®Google Scholar
• Dumitru R, Navarathna DH, Semighini CP, Elowsky CG, Dumitru RV, Dignard D, et al. In vivo and in vitro anaerobic mating in Candida albicans. Eukaryot Cell 2007; 6:465 - 72; http://dx.doi.org/10.1128/EC.00316-06; PMID: 17259544
   PubMed Web of Science ®Google Scholar
• Cowen LE, Lindquist S. Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi. Science 2005; 309:2185 - 9; http://dx.doi.org/10.1126/science.1118370; PMID: 16195452
   PubMed Web of Science ®Google Scholar