Supplemental material
General Xenobiochemistry
Bottom-up physiologically based pharmacokinetic modelling for predicting the human pharmacokinetic profiles of the ester prodrug MGS0274 and its active metabolite MGS0008, a metabotropic glutamate 2/3 receptor agonist
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Kohnosuke KinoshitaDrug Metabolism and Pharmacokinetics, Drug Safety and Pharmacokinetics Laboratories, Research Headquarters, Taisho Pharmaceutical Co., Ltd., Saitama, Japanhttps://orcid.org/0000-0003-4026-5129
https://orcid.org/0000-0003-4026-5129, &