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Research Article
Recombinant human thrombopoietin (rhTPO) of different dosing regimens for refractory/relapsed primary immune thrombocytopenia: a multicenter, randomized controlled trial and pharmacokinetics study
Xiaofan Liu1 State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Tianjin, China
https://orcid.org/0000-0002-9911-4491View further author information
Yusheng Bai2 Department of Hematology, Traditional Chinese Medical Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, ChinaView further author information
, Tao Wang3 Department of Hematology, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, ChinaView further author information
, Yanping Song4 Department of Hematology, Xi’an Central Hospital, Xi’an, Shaanxi, ChinaView further author information
, Feng Sun5 Department of Hematology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, ChinaView further author information
, Ruixiang Xia6 Department of Hematology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, ChinaView further author information
, Feiyue Zhu7 Department of Hematology, Loudi Central Hospital, Loudi, Hunan, ChinaView further author information
, Jun Ma8 Department of Hematology, Harbin Institute of Hematology and Oncology, Harbin, Heilongjiang, ChinaView further author information
, Quanyi Lu9 Department of Hematology, Zhongshan Hospital, Xiamen University, Xiamen, Fujian, ChinaView further author information
, Xu Ye10 Department of Hematology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, ChinaView further author information
, Xinrong Zhan11 Department of Hematology, Xinxiang Central Hospital, Xinxiang, Henan, ChinaView further author information
, Linjie Li12 Department of Hematology, Lishui Central Hospital, Lishui, Zhejiang, ChinaView further author information
, Xinhong Guo13 Department of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, ChinaView further author information
, Shuqin Cheng14 Department of Hematology, Guangzhou Panyu Central Hospital, Guangzhou, Guangdong, ChinaView further author information
, Yan Li15 Department of Hematology, The First Hospital of China Medical University, Shenyang, Liaoning, ChinaView further author information
, Zhiqiang Guo16 Department of Hematology, Zhengzhou Central Hospital, Zhengzhou, Henan, ChinaView further author information
, Youhua Chen17 Department of Hematology, Renmin Hospital of Wuhan University, Hubei General Hospital, Wuhan, Hubei, ChinaView further author information
, Shenxian Qian18 Department of Hematology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, ChinaView further author information
, Ling Qin19 Department of Hematology, The First Affiliated Hospital of Henan Technology University, Luoyang, Henan, ChinaView further author information
, Qing Zhang20 Department of Hematology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, ChinaView further author information
, Sunqiong Cao21 Medical Department, Shenyang Sunshine Pharmaceuticals Co. Ltd, Shenyang, Liaoning, ChinaView further author information
& Renchi Yang1 State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Tianjin, ChinaCorrespondence[email protected]
https://orcid.org/0000-0003-3741-8518View further author information
Article: 2157806
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Received 02 Aug 2022, Accepted 07 Dec 2022, Published online: 03 Jan 2023
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