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Research Papers
New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization
Hamada H. H. Mohammeda Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt;b Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, EgyptView further author information
, Amer Ali Abd El-Hafeezc Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA;d Cancer Biology Department, Pharmacology and Experimental Oncology Unit, National Cancer Institute, Cairo University, Cairo, EgyptView further author information
, Kareem Ebeide Department of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia, Egypt;f Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA;g Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Manufacturing, Deraya University, New Minia City, Minia, EgyptView further author information
, Aml I. Mekkawyf Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA;h Department of Pharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, Sohag University, Sohag, EgyptView further author information
, Mohammed A. S. Abourehabi Department of Pharmaceutics, Faculty of Pharmacy, Umm Al Qura University, Makkah, Saudi ArabiaView further author information
, Emad I. Wafaf Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USAView further author information
, Suhaila O. Alhaj-Sulimanf Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USAView further author information
, Aliasger K. Salemf Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, USA;j Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USACorrespondence[email protected]
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, View further author information
Pradipta Ghoshc Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA;k Department of Medicine, University of California San Diego, La Jolla, CA, USA;l Rebecca and John Moore Comprehensive Cancer Center, University of California San Diego, La Jolla, CA, USA;m Veterans Affairs Medical Center, La Jolla, CA, USAView further author information
, Gamal El-Din A. Abuo-Rahmaa Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt;n Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Deraya University, Minia, EgyptCorrespondence[email protected]
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, View further author information
Alaa M. Hayallaho Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt;p Pharmaceutical Chemistry Department, Faculty of Pharmacy, Sphinx University, New Assiut, EgyptView further author information
& Samar H. Abbasa Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, EgyptCorrespondence[email protected]
https://orcid.org/0000-0002-9586-2644View further author information
show allhttps://orcid.org/0000-0002-9586-2644View further author information
Pages 1346-1363
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Received 24 Feb 2022, Accepted 26 Apr 2022, Published online: 11 May 2022
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