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Cancer Biology & Therapy
Volume 22, 2021 - Issue 3
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Bedside-to-Bench Report
Discovery of a rare GKAP1-NTRK2 fusion in a pediatric low-grade glioma, leading to targeted treatment with TRK-inhibitor larotrectinib
Lily Delanda Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden;b Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
https://orcid.org/0000-0003-0338-4911View further author information
Simon Keanec Translational Medicine, School of Health Sciences, University of Skövde, Skövde, Sweden
https://orcid.org/0000-0002-0471-6896View further author information
Thomas Olsson Bontelld Department of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden;e Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenView further author information
, Helene Sjögrena Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, SwedenView further author information
, Henrik Fagmand Department of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden
https://orcid.org/0000-0001-5853-6295View further author information
Ingrid Øraf Department of Clinical Sciences, Lund University Hospital, Lund, Sweden;g HOPE/ITCC Phase I/II Trial Unit, Pediatric Oncology, Karolinska Hospital, Stockholm, Sweden
https://orcid.org/0000-0002-3931-4125View further author information
Esther De La Cuestah Pharmaceuticals, Global Medical Affairs – Oncology, Bayer U.S., Whippany, USAView further author information
, Magnus Tiselli Department of Clinical Neuroscience and Rehabilitation, Sahlgrenska University Hospital, Gothenburg, SwedenView further author information
, Jonas A Nilssonj Sahlgrenska Cancer Center, Department of Laboratory Medicine Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
https://orcid.org/0000-0003-0346-6837View further author information
Katarina Ejeskärc Translational Medicine, School of Health Sciences, University of Skövde, Skövde, SwedenView further author information
, Magnus Sabelk Childhood Cancer Centre, Queen Silvia Children’s Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden;l Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenCorrespondence[email protected]
https://orcid.org/0000-0002-3072-657XView further author information
Frida Abela Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden;b Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenCorrespondence[email protected]
https://orcid.org/0000-0001-6958-4487View further author information
Pages 184-195
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Received 25 Nov 2020, Accepted 25 Feb 2021, Published online: 05 Apr 2021
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