Supplemental material
Cell Cycle
Volume 14, 2015 - Issue 15
Related Research Data
Acetylation Negatively Regulates Glycogen Phosphorylase by Recruiting Protein Phosphatase 1
Source:
Elsevier BV
AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling
Source:
Ovid Technologies (Wolters Kluwer Health)
Two mutations impair the stability and function of ubiquitin-activating enzyme (E1)
Source:
Wiley-Blackwell
Histone Deacetylase Inhibitors Synergize p300 Autoacetylation that Regulates Its Transactivation Activity and Complex Formation
Source:
American Association for Cancer Research (AACR)
5'-AMP-Activated Protein Kinase (AMPK) Is Induced by Low-Oxygen and Glucose Deprivation Conditions Found in Solid-Tumor Microenvironments
Source:
American Society for Microbiology
Hypoxia-inducible Factor 1α (HIF-1α) Protein Is Rapidly Degraded by the Ubiquitin-Proteasome System under Normoxic Conditions ITS STABILIZATION BY HYPOXIA DEPENDS ON REDOX-INDUCED CHANGES
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
A New Family of Human Histone Deacetylases Related toSaccharomyces cerevisiaeHDA1p
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Hypoxia-Inducible Factors, Stem Cells, and Cancer
Source:
Elsevier BV
Histone Deacetylase Inhibitors Repress the Transactivation Potential of Hypoxia-inducible Factors Independently of Direct Acetylation of HIF-α
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Regulation and Destabilization of HIF-1α by ARD1-Mediated Acetylation
Source:
Elsevier BV
Regulation of Cellular Metabolism by Protein Lysine Acetylation
Source:
American Association for the Advancement of Science (AAAS)
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
Source:
Elsevier BV
AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol
Source:
Figshare
Hypoxia Triggers AMPK Activation through Reactive Oxygen Species-Mediated Activation of Calcium Release-Activated Calcium Channels
Source:
American Society for Microbiology
Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch
Source:
American Association for the Advancement of Science (AAAS)
Effects of Histone Deacetylase Inhibitors on HIF-1
Source:
Informa UK Limited
Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes
Source:
Elsevier BV
AMP-activated Protein Kinase Regulates β-Catenin Transcription via Histone Deacetylase 5
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Regulation of the HIF-1α level is essential for hematopoietic stem cells
Source:
Elsevier BV
AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol
Source:
Figshare
Multiplex Genome Engineering Using CRISPR/Cas Systems
Source:
American Association for the Advancement of Science (AAAS)
Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux
Source:
American Association for the Advancement of Science (AAAS)
Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5
Source:
Proceedings of the National Academy of Sciences
HDAC6 is a microtubule-associated deacetylase
Source:
Springer Nature
Histone Deacetylase Inhibitors Induce VHL and Ubiquitin-Independent Proteasomal Degradation of Hypoxia-Inducible Factor 1
Source:
American Society for Microbiology
The von Hippel–Lindau protein, HIF hydroxylation, and oxygen sensing
Source:
Elsevier BV
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing
Source:
American Association for the Advancement of Science (AAAS)
HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation
Source:
Proceedings of the National Academy of Sciences
AMP-ACTIVATED PROTEIN KINASE REGULATES GLUT4 TRANSCRIPTION BY PHOSPHORYLATING HISTONE DEACETYLASE 5
Source:
American Diabetes Association
The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men.
Source:
Springer Science and Business Media LLC
Class II Histone Deacetylases Are Associated with VHL-Independent Regulation of Hypoxia-Inducible Factor 1α
Source:
American Association for Cancer Research (AACR)
Regulation of hypoxia-inducible factor 1 is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway
Source:
Proceedings of the National Academy of Sciences
Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development
Source:
American Society for Microbiology
AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol
Source:
figshare Academic Research System
FK228 inhibits Hsp90 chaperone function in K562 cells via hyperacetylation of Hsp70
Source:
Elsevier BV
Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Class II Histone Deacetylases: from Sequence to Function, Regulation, and Clinical Implication
Source:
American Society for Microbiology
Interaction between HIF-1α (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1α
Source:
Federation of European Biochemical Societies. Published by Elsevier B.V.
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
Source:
Proceedings of the National Academy of Sciences
Targeting of HIF-alpha to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation
Source:
American Association for the Advancement of Science (AAAS)
Histone Deacetylase Inhibitors: The Epigenetic Therapeutics That Repress Hypoxia-Inducible Factors
Source:
Hindawi Limited
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
Source:
Springer Science and Business Media LLC
Hydroxylation of HIF-1: Oxygen Sensing at the Molecular Level
Source:
American Physiological Society
Hypoxia-Inducible Factors in Physiology and Medicine
Source:
Elsevier BV
Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
Source:
Springer Nature
Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
Source:
Elsevier BV
AMP-activated protein kinase activity during metabolic rate depression in the hypoxic goldfish, Carassius auratus
Source:
The Company of Biologists
Cardiac-Specific Overexpression of HIF-1α Prevents Deterioration of Glycolytic Pathway and Cardiac Remodeling in Streptozotocin-Induced Diabetic Mice
Source:
Elsevier BV
Arrest-defective-1 Protein, an Acetyltransferase, Does Not Alter Stability of Hypoxia-inducible Factor (HIF)-1α and Is Not Induced by Hypoxia or HIF
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Carboxyl-Terminal Transactivation Activity of Hypoxia-Inducible Factor 1 Is Governed by a von Hippel-Lindau Protein-Independent, Hydroxylation-Regulated Association with p300/CBP
Source:
American Society for Microbiology
HIF-1 regulation: not so easy come, easy go
Source:
Elsevier BV
Histone Deacetylase (HDAC) Inhibitors with a Novel Connecting Unit Linker Region Reveal a Selectivity Profile for HDAC4 and HDAC5 with Improved Activity against Chemoresistant Cancer Cells
Source:
American Chemical Society (ACS)
Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation
Source:
Wiley
HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor
Source:
Elsevier BV
Enzymatic Activity Associated with Class II HDACs Is Dependent on a Multiprotein Complex Containing HDAC3 and SMRT/N-CoR
Source:
Elsevier BV
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression.
Source:
Springer Science and Business Media LLC
Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase
Source:
Elsevier BV
Nuclear Import of Histone Deacetylase 5 by Requisite Nuclear Localization Signal Phosphorylation
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Hypoxia Inducible Factor-1 as a Target for Neurodegenerative Diseases
Source:
Bentham Science Publishers Ltd.
Hypoxia-Inducible Factor 1 and Cardiovascular Disease
Source:
Annual Reviews
Identification of a signal-responsive nuclear export sequence in class II histone deacetylases.
Source:
American Society for Microbiology
Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy
Source:
Proceedings of the National Academy of Sciences
Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
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