Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides

Kaori KobayashiDepartment of Chemistry, Graduate School of Science and Engineering, Tokyo Metropolitan University, Hachioji-shi, Tokyo, Japan

Thomas A. GuilliamGenome Damage and Stability Center, School of Life Sciences, University of Sussex, Brighton, UK

Masataka TsudaDepartment of Radiation Genetics, Graduate School of Medicine, Kyoto University, Yoshidakonoe, Sakyo-ku, Kyoto, Japan

Junpei YamamotoDivision of Chemistry, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka, Japan

Laura J. BaileyGenome Damage and Stability Center, School of Life Sciences, University of Sussex, Brighton, UK

Shigenori IwaiDivision of Chemistry, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka, Japan

Shunichi TakedaDepartment of Radiation Genetics, Graduate School of Medicine, Kyoto University, Yoshidakonoe, Sakyo-ku, Kyoto, Japan

Aidan J. DohertyGenome Damage and Stability Center, School of Life Sciences, University of Sussex, Brighton, UKCorrespondence[email protected] [email protected]

Kouji HirotaDepartment of Chemistry, Graduate School of Science and Engineering, Tokyo Metropolitan University, Hachioji-shi, Tokyo, JapanCorrespondence[email protected] [email protected]

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