Supplemental material
RNA Biology
Volume 16, 2019 - Issue 12
Research Paper
Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo
, 
, &
J. David BarrassWellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UKhttps://orcid.org/0000-0002-1624-8276View further author information
https://orcid.org/0000-0002-1624-8276View further author information, & Jean D. BeggsWellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UKhttps://orcid.org/0000-0002-8179-6519View further author information
https://orcid.org/0000-0002-8179-6519View further author informationRelated Research Data
Counting on co-transcriptional splicing.
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Faculty of 1000 Ltd
Link of NTR-Mediated Spliceosome Disassembly with DEAH-Box ATPases Prp2, Prp16, and Prp22
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American Society for Microbiology
A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing.
Source:
American Society for Microbiology
Spliceosome structure and function.
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Global analysis of nascent RNA reveals transcriptional pausing in terminal exons.
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Functional splicing network reveals extensive regulatory potential of the core spliceosomal machinery
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Structural basis of pre-mRNA splicing
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American Association for the Advancement of Science (AAAS)
Structure of the yeast spliceosomal postcatalytic P complex.
Source:
American Association for the Advancement of Science (AAAS)
Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast.
Source:
Elsevier BV
A mechanism to enhance mRNA splicing fidelity: the RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates.
Source:
Elsevier BV
Incomplete splicing, cell division defects, and hematopoietic blockage in dhx8 mutant zebrafish.
Source:
Wiley
Structure of a yeast catalytic step I spliceosome at 3.4 Å resolution
Source:
American Association for the Advancement of Science (AAAS)
Mechanistic insights into precursor messenger RNA splicing by the spliceosome
Source:
Springer Science and Business Media LLC
Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling
Source:
Springer Science and Business Media LLC
Exon ligation is proofread by the DExD/H-box ATPase Prp22p.
Source:
Springer Science and Business Media LLC
Identification of new branch points and unconventional introns in Saccharomyces cerevisiae
Source:
Cold Spring Harbor Laboratory
Arrested yeast splicing complexes indicate stepwise snRNP recruitment during in vivo spliceosome assembly.
Source:
Cold Spring Harbor Laboratory
Competition between Pre-mRNAs for the Splicing Machinery Drives Global Regulation of Splicing
Source:
Elsevier BV
An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8
Source:
Cambridge University Press
Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast
Source:
Oxford University Press (OUP)
Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo
Source:
Taylor & Francis
Genetics and Biochemistry Remain Essential in the Structural Era of the Spliceosome
Source:
Elsevier BV
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
Source:
Elsevier BV
Suppression of Multiple Substrate Mutations by Spliceosomal prp8 Alleles Suggests Functional Correlations with Ribosomal Ambiguity Mutants
Source:
Elsevier BV
A Conformational Rearrangement in the Spliceosome Sets the Stage for Prp22-Dependent mRNA Release
Source:
Elsevier BV
Nineteen complex–related factor Prp45 is required for the early stages of cotranscriptional spliceosome assembly
Source:
Cold Spring Harbor Laboratory
A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing
Source:
Elsevier BV
Structures of the fully assembled Saccharomyces cerevisiae spliceosome before activation
Source:
American Association for the Advancement of Science (AAAS)
Widespread alternative and aberrant splicing revealed by lariat sequencing
Source:
Oxford University Press (OUP)
RiboSys, a high-resolution, quantitative approach to measure the in vivo kinetics of pre-mRNA splicing and 3 '-end processing in Saccharomyces cerevisiae
Source:
Cold Spring Harbor Laboratory
Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes
Source:
Springer Science and Business Media LLC
An alternative splicing network links cell-cycle control to apoptosis.
Source:
Elsevier BV
DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps.
Source:
Cold Spring Harbor Laboratory
Coupling mRNA processing with transcription in time and space
Source:
Springer Science and Business Media LLC
RNA helicases in splicing.
Source:
Informa UK Limited
Functional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing.
Source:
Cold Spring Harbor Laboratory
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