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Autophagy Volume 11, 2015 - Issue 8
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Basic Research Paper

The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux

Valerie R WiersmaUniversity of Groningen; University Medical Center Groningen; Department of Surgery; Translational Surgical Oncology; Groningen, The Netherlands
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Marco de BruynUniversity of Groningen; University Medical Center Groningen; Department of Gynecology & Obstetrics; Groningen, The Netherlands
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Yunwei WeiUniversity of Groningen; University Medical Center Groningen; Department of Surgery; Translational Surgical Oncology; Groningen, The Netherlands;Oncological and Endoscopic Surgery Department; First Affiliated Hospital of Harbin Medical University; China
,
Robert J van GinkelUniversity of Groningen; University Medical Center Groningen; Department of Surgery; Translational Surgical Oncology; Groningen, The Netherlands
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Mitsuomi HirashimaDepartment of Immunology & Immunopathology; Kagawa University Faculty of Medicine; Kagawa, Japan;GalPharma Co., Ltd.; Kagawa, Japan
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Toshiro NikiDepartment of Immunology & Immunopathology; Kagawa University Faculty of Medicine; Kagawa, Japan;GalPharma Co., Ltd.; Kagawa, Japan
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Nozomu NishiDivision of Research Instrument and Equipment; Life Science Research Center; Kagawa University; Kagawa, Japan
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Jin ZhouHealth Ministry Key Lab of Cell Transplantation; Heilongjiang Institute of Hematology and Oncology; Department of Hematology; First Affiliated Hospital; Harbin Medical University; Harbin, China
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Simon D PouwelsUniversity of Groningen; University Medical Center Groningen; Experimental pulmonology and inflammation research; GRIAC Research Institute; Department of Pathology and Medical Biology; Groningen
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Douwe F SamploniusUniversity of Groningen; University Medical Center Groningen; Department of Surgery; Translational Surgical Oncology; Groningen, The Netherlands
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Hans W NijmanUniversity of Groningen; University Medical Center Groningen; Department of Gynecology & Obstetrics; Groningen, The Netherlands
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Paul EggletonExeter University Medical School; Devon, UK
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Wijnand HelfrichUniversity of Groningen; University Medical Center Groningen; Department of Surgery; Translational Surgical Oncology; Groningen, The Netherlands;Health Ministry Key Lab of Cell Transplantation; Heilongjiang Institute of Hematology and Oncology; Department of Hematology; First Affiliated Hospital; Harbin Medical University; Harbin, China
&
Edwin BremerUniversity of Groningen; University Medical Center Groningen; Department of Surgery; Translational Surgical Oncology; Groningen, The Netherlands;Exeter University Medical School; Devon, UKCorrespondence[email protected]
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Pages 1373-1388 | Received 10 Oct 2014, Accepted 12 Jun 2015, Published online: 14 Aug 2015