Autophagy, Volume 11, Issue 8 (2015)

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Autophagy, Volume 11, Issue 8 (2015)

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Editor's Corner

Editorial
Wouter G van Doorn, December 13, 1951–May 16, 2015
Hans van den Berg & Daniel J Klionsky
Page: 1197
Published online: 14 Aug 2015
AbstractforWouter G van Doorn, December 13, 1951–May 16, 2015 | Full Text | PDF (89.5 KB)
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Review

Review
Glutaminolysis and autophagy in cancer
Victor H Villar, Faten Merhi, Mojgan Djavaheri-Mergny & Raúl V Durán
Pages: 1198-1208
Published online: 14 Aug 2015
AbstractforGlutaminolysis and autophagy in cancer | Full Text | References | PDF (603.7 KB)
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Basic Brief Report

Brief Report
Loss of Drosophila Vps16A enhances autophagosome formation through reduced Tor activity
Szabolcs Takáts, Ágnes Varga, Karolina Pircs & Gábor Juhász
Pages: 1209-1215
Published online: 14 Aug 2015
AbstractforLoss of Drosophila Vps16A enhances autophagosome formation through reduced Tor activity | Full Text | References | PDF (764 KB) | Supplemental
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Brief Report
Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy
Jie Li, Wei Qi, Guo Chen, Du Feng, Jinhua Liu, Biao Ma, Changqian Zhou, Chenglong Mu, Weilin Zhang, Quan Chen & Yushan Zhu
Pages: 1216-1229
Published online: 14 Aug 2015
AbstractforMitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy | Full Text | References | PDF (1.5 MB) | Supplemental
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Basic Research Paper

Article
Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells
Byong Hoon Yoo, Anna Zagryazhskaya, Yongling Li, Ananda Koomson, Iman Aftab Khan, Takehiko Sasazuki, Senji Shirasawa & Kirill V Rosen
Pages: 1230-1246
Published online: 14 Aug 2015
AbstractforUpregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells | Full Text | References | PDF (922.6 KB) | Supplemental
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Article
A defect of the vacuolar putative lipase Atg15 accelerates degradation of lipid droplets through lipolysis
Yuichiro Maeda, Masahide Oku & Yasuyoshi Sakai
Pages: 1247-1258
Published online: 14 Aug 2015
AbstractforA defect of the vacuolar putative lipase Atg15 accelerates degradation of lipid droplets through lipolysis | Full Text | References | PDF (893.7 KB) | Supplemental
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Article
A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission
Jing Zhou, Guobing Li, Yi Zheng, Han-Ming Shen, Xiaoye Hu, Qian-Liang Ming, Cheng Huang, Peng Li & Ning Gao
Pages: 1259-1279
Published online: 14 Aug 2015
AbstractforA novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission | Full Text | References | PDF (2.9 MB) | Supplemental
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Article
Macrophage autophagy protects against liver fibrosis in mice
Jasper Lodder, Timothé Denaës, Marie-Noële Chobert, JingHong Wan, Jamel El-Benna, Jean-Michel Pawlotsky, Sophie Lotersztajn & Fatima Teixeira-Clerc
Pages: 1280-1292
Published online: 14 Aug 2015
AbstractforMacrophage autophagy protects against liver fibrosis in mice | Full Text | References | PDF (1.4 MB)
  • 7390 Views
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Article
Burkholderia pseudomallei survival in lung epithelial cells benefits from miRNA-mediated suppression of ATG10
Qian Li, Yao Fang, Pan Zhu, Chun-yan Ren, Hai Chen, Jiang Gu, Yin-ping Jia, Kun Wang, Wen-de Tong, Wei-jun Zhang, Jing Pan, Dong-shui Lu, Bin Tang & Xu-hu Mao
Pages: 1293-1307
Published online: 14 Aug 2015
AbstractforBurkholderia pseudomallei survival in lung epithelial cells benefits from miRNA-mediated suppression of ATG10 | Full Text | References | PDF (1.8 MB) | Supplemental
  • 1714 Views
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Article
ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation
Huiwen Song, Jun Pu, Lin Wang, Lihua Wu, Jianmin Xiao, Qigong Liu, Jun Chen, Min Zhang, Yang Liu, Mingke Ni, Jinggang Mo, Yunliang Zheng, Deli Wan, XiongJiu Cai, Yaping Cao, Weiyi Xiao, Lei Ye, Enyuan Tu, Zhihai Lin, Jianxin Wen, Xiaoling Lu, Jian He, Yi Peng, Jing Su, Heng Zhang, Yongxiang Zhao, Meihua Lin & Zhiyong Zhang
Pages: 1308-1325
Published online: 14 Aug 2015
AbstractforATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation | Full Text | References | PDF (1.4 MB) | Supplemental
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Article
Export-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts
Marcus Nordgren, Tânia Francisco, Celien Lismont, Lore Hennebel, Chantal Brees, Bo Wang, Paul P Van Veldhoven, Jorge E Azevedo & Marc Fransen
Pages: 1326-1340
Published online: 14 Aug 2015
AbstractforExport-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts | Full Text | References | PDF (788.7 KB) | Supplemental
  • 2656 Views
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Article
Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling
Rohit A Sinha, Brijesh K Singh, Jin Zhou, Yajun Wu, Benjamin L Farah, Kenji Ohba, Ronny Lesmana, Jessica Gooding, Boon-Huat Bay & Paul M Yen
Pages: 1341-1357
Published online: 14 Aug 2015
AbstractforThyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling | Full Text | References | PDF (1.8 MB) | Supplemental
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Article
Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis
Myungjin Kim, Ian Semple, Boyoung Kim, Alexandra Kiers, Samuel Nam, Hwan-Woo Park, Haeli Park, Seung-Hyun Ro, Jeong-Sig Kim, Gábor Juhász & Jun Hee Lee
Pages: 1358-1372
Published online: 14 Aug 2015
AbstractforDrosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis | Full Text | References | PDF (1.6 MB) | Supplemental
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Article
The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux
Valerie R Wiersma, Marco de Bruyn, Yunwei Wei, Robert J van Ginkel, Mitsuomi Hirashima, Toshiro Niki, Nozomu Nishi, Jin Zhou, Simon D Pouwels, Douwe F Samplonius, Hans W Nijman, Paul Eggleton, Wijnand Helfrich & Edwin Bremer
Pages: 1373-1388
Published online: 14 Aug 2015
AbstractforThe epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux | Full Text | References | PDF (1.8 MB) | Supplemental
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Article
Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo
Mehrdad Alirezaei, Claudia T Flynn, Malcolm R Wood, Stephanie Harkins & J Lindsay Whitton
Pages: 1389-1407
Published online: 14 Aug 2015
AbstractforCoxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo | Full Text | References | PDF (2.2 MB)
  • 2377 Views
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Toolbox

Article
Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay
Sonja Aits, Jennifer Kricker, Bin Liu, Anne-Marie Ellegaard, Saara Hämälistö, Siri Tvingsholm, Elisabeth Corcelle-Termeau, Søren Høgh, Thomas Farkas, Anna Holm Jonassen, Irina Gromova, Monika Mortensen & Marja Jäättelä
Pages: 1408-1424
Published online: 14 Aug 2015
AbstractforSensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay | Full Text | References | PDF (1.7 MB) | Supplemental
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Letter to the Editor

Letter
The problem of pyridinyl imidazole class inhibitors of MAPK14/p38α and MAPK11/p38β in autophagy research
Manoj B Menon, Sonam Dhamija, Alexey Kotlyarov & Matthias Gaestel
Pages: 1425-1427
Published online: 14 Aug 2015
AbstractforThe problem of pyridinyl imidazole class inhibitors of MAPK14/p38α and MAPK11/p38β in autophagy research | Full Text | References | PDF (333.1 KB)
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Autophagic Punctum

Article
Coupling mitogenesis and mitophagy for longevity
Konstantinos Palikaras, Eirini Lionaki & Nektarios Tavernarakis
Pages: 1428-1430
Published online: 14 Aug 2015
AbstractforCoupling mitogenesis and mitophagy for longevity | Full Text | PDF (237.9 KB)
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Article
NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?
Célia A Aveleira, Mariana Botelho & Cláudia Cavadas
Pages: 1431-1433
Published online: 14 Aug 2015
AbstractforNPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? | Full Text | PDF (104.3 KB)
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Article
Axonal autophagosomes use the ride-on service for retrograde transport toward the soma
Xiu-Tang Cheng, Bing Zhou, Mei-Yao Lin, Qian Cai & Zu-Hang Sheng
Pages: 1434-1436
Published online: 14 Aug 2015
AbstractforAxonal autophagosomes use the ride-on service for retrograde transport toward the soma | Full Text | PDF (232.1 KB)
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Article
Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion
Caroline Mauvezin & Thomas P Neufeld
Pages: 1437-1438
Published online: 14 Aug 2015
AbstractforBafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion | Full Text | PDF (97 KB)
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Corrigendum

Correction
Corrigendum
Page: 1439
Published online: 14 Aug 2015
CitationforCorrigendum | Full Text | PDF (30.1 KB)
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