Supplemental material
Research Paper
Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies
, 
, , , , , & show all
Bob AsselberghVIB-UAntwerp Center for Molecular Neurology, Antwerp, Belgiumhttp://orcid.org/0000-0003-2784-2470
http://orcid.org/0000-0003-2784-2470, , , Jean-Pierre TimmermansLaboratory of Cell Biology & Histology, Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, Antwerp, Belgiumhttp://orcid.org/0000-0003-2506-6252
http://orcid.org/0000-0003-2506-6252, , & Vincent TimmermanPeripheral Neuropathy Research Group, Institute Born Bunge and University of Antwerp, Antwerp, BelgiumCorrespondence[email protected]
http://orcid.org/0000-0002-2162-0933
http://orcid.org/0000-0002-2162-0933 show allRelated Research Data
Identification of the Drosophila Ortholog of HSPB8 IMPLICATION OF HSPB8 LOSS OF FUNCTION IN PROTEIN FOLDING DISEASES
Source:
Elsevier BV
Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease
Source:
Springer Nature
Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Autophagy as an Emerging Common Pathomechanism in Inherited Peripheral Neuropathies
Source:
Frontiers Media S.A.
Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities
Source:
Elsevier BV
A pyramid approach to subpixel registration based on intensity
Source:
Institute of Electrical and Electronics Engineers (IEEE)
Heat Shock Proteins 27 and 70: Anti-Apoptotic Proteins with Tumorigenic Properties
Source:
Informa UK Limited
HspB1 silences translation of PDZ-RhoGEF by enhancing miR-20a and miR-128 expression to promote neurite extension
Source:
Elsevier BV
HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis.
Source:
Informa UK Limited
Autophagy modulation as a potential therapeutic target for diverse diseases
Source:
Springer Nature
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
Source:
Rockefeller University Press
HSP27 Is a Ubiquitin-Binding Protein Involved in I-κBα Proteasomal Degradation
Source:
American Society for Microbiology
The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold
Source:
Elsevier BV
The role of Hsp27 and actin in the regulation of movement in human cancer cells responding to heat shock
Source:
Springer Science and Business Media LLC
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1
Source:
Informa UK Limited
Molecular Chaperones in the Pathogenesis of Amyotrophic Lateral Sclerosis: The Role of HSPB1
Source:
Wiley-Blackwell
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy
Source:
Springer Nature
HspB8 Participates in Protein Quality Control by a Non-chaperone-like Mechanism That Requires eIF2α Phosphorylation
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Small Heat-Shock Protein HSPB1 Mutants Stabilize Microtubules in Charcot-Marie-Tooth Neuropathy
Source:
Society for Neuroscience
Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies
Source:
Taylor & Francis
Molecular Biology of Small Heat Shock Proteins associated with Peripheral Neuropathies
Source:
John Wiley & Sons, Ltd
The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity
Source:
Oxford University Press (OUP)
The Functional Landscape of Hsp27 Reveals New Cellular Processes such as DNA Repair and Alternative Splicing and Proposes Novel Anticancer Targets
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Barcoding heat shock proteins to human diseases: looking beyond the heat shock response
Source:
The Company of Biologists
HspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins
Source:
MDPI AG
Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies
Source:
Taylor & Francis
Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin–proteasome pathways
Source:
Elsevier BV
Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology
Source:
Springer Science and Business Media LLC
Novel insights in the disease biology of mutant small heat shock proteins in neuromuscular diseases
Source:
Oxford University Press (OUP)
The NMR structure of the p62 PB1 domain, a key protein in autophagy and NF-κB signaling pathway
Source:
Springer Nature
The atypical PKC‐interacting protein p62 channels NF‐κB activation by the IL‐1–TRAF6 pathway
Source:
Wiley
Improved structure, function and compatibility for CellProfiler
Source:
Oxford University Press (OUP)
Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling
Source:
Elsevier Inc.
Monitoring autophagy by electron microscopy in Mammalian cells.
Source:
Elsevier
Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
Source:
Wiley
Impairment of starvation-induced and constitutive autophagy inAtg7-deficient mice
Source:
Rockefeller University Press
PB1 Domain-Dependent Signaling Complex Is Required for Extracellular Signal-Regulated Kinase 5 Activation
Source:
American Society for Microbiology
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients
Source:
Springer Nature
Genome engineering using the CRISPR-Cas9 system
Source:
Springer Science and Business Media LLC
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification.
Source:
Springer Science and Business Media LLC
Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy
Source:
eLife Sciences Publications, Ltd
How to Interpret LC3 Immunoblotting
Source:
Informa UK Limited
Neuronal macroautophagy: From development to degeneration
Source:
Elsevier BV
Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
Source:
Elsevier BV
Autophagy and neurodegeneration: when the cleaning crew goes on strike
Source:
Elsevier BV
Expansion microscopy with conventional antibodies and fluorescent proteins
Source:
Springer Nature
p62 at the Crossroads of Autophagy, Apoptosis, and Cancer
Source:
Elsevier BV
Large Potentials of Small Heat Shock Proteins
Source:
(:unav)
Transcriptional regulation of small HSP—HSF1 and beyond
Source:
Elsevier BV
Linking provided by
