Autophagy, Volume 15, Issue 6 (2019)

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Autophagy, Volume 15, Issue 6 (2019)

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Research Paper

Article
A facile forward-genetic screen for Arabidopsis autophagy mutants reveals twenty-one loss-of-function mutations disrupting six ATG genes
Pierce G. Young, Michael J. Passalacqua, Kevin Chappell, Roxanna J. Llinas & Bonnie Bartel
Pages: 941-959
Published online: 08 Feb 2019
AbstractforA facile forward-genetic screen for Arabidopsis autophagy mutants reveals twenty-one loss-of-function mutations disrupting six ATG genes | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
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Article
The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion
Yu Xia, Na Liu, Xiuxiu Xie, Guoyu Bi, Hongping Ba, Lin Li, Jinxia Zhang, Xiaofei Deng, Yao Yao, Zhaohui Tang, Binjiao Yin, Jing Wang, Kan Jiang, Zhuoya Li, Yongwon Choi, Feili Gong, Xiang Cheng, John J O’Shea, Jae Jin Chae, Arian Laurence & Xiang-Ping Yang
Pages: 960-975
Published online: 29 Jan 2019
AbstractforThe macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
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Article
Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells
Alexander Agrotis, Niccolo Pengo, Jemima J. Burden & Robin Ketteler
Pages: 976-997
Published online: 01 Feb 2019
AbstractforRedundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells | Full Text | References | PDF (5.4 MB) | EPUB | Supplemental
  • 10458 Views
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Open Access
Article
Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR
Bin Ye, Quan Wang, Haixia Hu, Yilin Shen, Cui Fan, Penghui Chen, Yan Ma, Hao Wu & Mingliang Xiang
Pages: 998-1016
Published online: 01 Feb 2019
AbstractforRestoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR | Full Text | References | PDF (4.6 MB) | EPUB | Supplemental
  • 4286 Views
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Open Access
Article
YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization
Yang Xu, Jinqi Ren, Xiaolong He, Han Chen, Taotao Wei & Wei Feng
Pages: 1017-1030
Published online: 27 Jan 2019
AbstractforYWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
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Article
Gyp1 has a dual function as Ypt1 GAP and interaction partner of Atg8 in selective autophagy
Anne Lisa Mitter, Petra Schlotterhose & Roswitha Krick
Pages: 1031-1050
Published online: 27 Jan 2019
AbstractforGyp1 has a dual function as Ypt1 GAP and interaction partner of Atg8 in selective autophagy | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
  • 1274 Views
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Article
Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies
Mansour Haidar, Bob Asselbergh, Elias Adriaenssens, Vicky De Winter, Jean-Pierre Timmermans, Michaela Auer-Grumbach, Manisha Juneja & Vincent Timmerman
Pages: 1051-1068
Published online: 31 Jan 2019
AbstractforNeuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies | Full Text | References | PDF (4 MB) | EPUB | Supplemental
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Open Access
Article
Skeletal muscle-specific Prmt1 deletion causes muscle atrophy via deregulation of the PRMT6-FOXO3 axis
Seri Choi, Hyeon-Ju Jeong, Hyebeen Kim, Dahee Choi, Sung-Chun Cho, Je Kyung Seong, Seung-Hoi Koo & Jong-Sun Kang
Pages: 1069-1081
Published online: 05 Feb 2019
AbstractforSkeletal muscle-specific Prmt1 deletion causes muscle atrophy via deregulation of the PRMT6-FOXO3 axis | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 8579 Views
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Article
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle
Khalid Arhzaouy, Chrisovalantis Papadopoulos, Nina Schulze, Sara K. Pittman, Hemmo Meyer & Conrad C. Weihl
Pages: 1082-1099
Published online: 29 Jan 2019
AbstractforVCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle | Full Text | References | PDF (4.5 MB) | EPUB | Supplemental
  • 7877 Views
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Article
MIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy
Tianzhi Huang, Xuechao Wan, Angel A. Alvarez, C. David James, Xiao Song, Yongyong Yang, Namratha Sastry, Ichiro Nakano, Erik P. Sulman, Bo Hu & Shi-Yuan Cheng
Pages: 1100-1111
Published online: 31 Jan 2019
AbstractforMIR93 (microRNA -93) regulates tumorigenicity and therapy response of glioblastoma by targeting autophagy | Full Text | References | PDF (2.4 MB) | EPUB | Supplemental
  • 5343 Views
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Commentary

Article Commentary
Mitophagy and NAD+ inhibit Alzheimer disease
Evandro F. Fang
Pages: 1112-1114
Published online: 28 Mar 2019
AbstractforMitophagy and NAD+ inhibit Alzheimer disease | Full Text | References | PDF (599 KB) | EPUB
  • 8663 Views
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Article Commentary
Adventures in spacetime: circadian rhythms and the dynamics of protein catabolism
Mikhail Ryzhikov, Anna Ehlers & Jeffrey A. Haspel
Pages: 1115-1116
Published online: 27 Mar 2019
AbstractforAdventures in spacetime: circadian rhythms and the dynamics of protein catabolism | Full Text | References | PDF (660.4 KB) | EPUB
  • 670 Views
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Article Commentary
Reduced autophagy efficiency induces innate immune activation leading to neurodegeneration
Arvind K. Shukla & Edward Giniger
Pages: 1117-1119
Published online: 27 Mar 2019
AbstractforReduced autophagy efficiency induces innate immune activation leading to neurodegeneration | Full Text | References | PDF (530.8 KB) | EPUB
  • 1177 Views
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Article Commentary
RUBCNL/Pacer and RUBCN/Rubicon in regulation of autolysosome formation and lipid metabolism
Xiawei Cheng & Qiming Sun
Pages: 1120-1121
Published online: 27 Mar 2019
AbstractforRUBCNL/Pacer and RUBCN/Rubicon in regulation of autolysosome formation and lipid metabolism | Full Text | References | PDF (351.1 KB) | EPUB
  • 2288 Views
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Article Commentary
The BARA necessities of PtdIns 3-kinase activation in autophagy
Chunmei Chang, Lindsey N. Young & James H. Hurley
Pages: 1122-1123
Published online: 30 Mar 2019
AbstractforThe BARA necessities of PtdIns 3-kinase activation in autophagy | Full Text | References | PDF (546.8 KB) | EPUB
  • 1000 Views
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Correction

Correction
Correction
Page: 1124
Published online: 11 Mar 2019
CitationforCorrection | Full Text | PDF (383.3 KB) | EPUB
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Correction
Correction
Pages: 1125-1127
Published online: 28 Mar 2019
First Page PreviewforCorrection | Full Text | PDF (506 KB) | EPUB
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