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Autophagy Volume 18, 2022 - Issue 2
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Research Paper

Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders

Katrin Lindaa Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
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Elly I. Lewerissaa Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
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Anouk H. A. Verbovena Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
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Michele Gabrieleb Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy;c Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy;d Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USAView further author information
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Monica Fregaa Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The Netherlands;e Department of Clinical Neurophysiology, University of Twente, Enschede, The NetherlandsView further author information
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Teun M. Klein Gunnewieka Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The Netherlands;f Department of Anatomy, Radboudumc, Donders Institute for Brain, Cognition, and Behaviour, Nijmegen, The NetherlandsView further author information
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Lynn Devileea Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
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Edda Ulfertsa Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
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Marina Hommersoma Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
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Astrid Oudakkera Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
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Chantal Schoenmakera Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
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Hans van Bokhovena Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The Netherlands;g Department of Cognitive Neuroscience, Radboudumc, Donders Institute for Brain, Cognition and Behavior, Nijmegen, The NetherlandsView further author information
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Dirk Schubertg Department of Cognitive Neuroscience, Radboudumc, Donders Institute for Brain, Cognition and Behavior, Nijmegen, The NetherlandsView further author information
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Giuseppe Testab Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy;c Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, ItalyView further author information
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David A. Koolena Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
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Bert B.A. de Vriesa Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The NetherlandsView further author information
&
Nael Nadif Kasria Department of Human Genetics, Radboudumc, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, The Netherlands;g Department of Cognitive Neuroscience, Radboudumc, Donders Institute for Brain, Cognition and Behavior, Nijmegen, The NetherlandsCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7448-9289View further author information
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Pages 423-442 | Received 09 Sep 2020, Accepted 26 May 2021, Published online: 21 Jul 2021

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Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders
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