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Research paper

Metabolic stress induces a double-positive feedback loop between AMPK and SQSTM1/p62 conferring dual activation of AMPK and NFE2L2/NRF2 to synergize antioxidant defense

Eun-Ji Choia Research Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Seoul, Korea;b College of Pharmacy, Ajou University, Suwon, Gyeonggi-do, KoreaView further author information
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Hyun-Taek Oha Research Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Seoul, Korea;c Department of BioHealth Regulatory Science, Graduate School of Ajou University, Suwon, Gyeonggi-do, KoreaView further author information
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Seon-Hyeong Leed Division of Cancer Biology, Research Institute, National Cancer Center, Goyang, Gyeonggi-do, KoreaView further author information
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Chen-Song Zhange State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Fujian, Xiamen, ChinaView further author information
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Mengqi Lie State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Fujian, Xiamen, ChinaView further author information
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Soo-Youl Kimd Division of Cancer Biology, Research Institute, National Cancer Center, Goyang, Gyeonggi-do, KoreaView further author information
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Sunghyouk Parkf Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul, KoreaView further author information
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Tong-Shin Changa Research Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Seoul, KoreaView further author information
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Byung-Hoon Leea Research Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Seoul, KoreaView further author information
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Sheng-Cai Line State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Fujian, Xiamen, ChinaView further author information
&
Sang-Min Jeona Research Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, Seoul, Korea;b College of Pharmacy, Ajou University, Suwon, Gyeonggi-do, Korea;c Department of BioHealth Regulatory Science, Graduate School of Ajou University, Suwon, Gyeonggi-do, KoreaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0132-925XView further author information
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Received 07 Dec 2023, Accepted 22 May 2024, Published online: 10 Jul 2024

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