Pruning and thresholding approach for methylation risk scores in multi-ancestry populations

Junyu Chena Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GAUSAView further author information

Evan Gatevb Institute of Molecular Biology “Acad. Roumen Tsanev”, Sofia, Bulgaria;c Department of Medical Genetics, University of British Columbia, Vancouver, CanadaView further author information

Todd Eversona Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GAUSA;d Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GeorgiaView further author information

Karen N. Conneelye Department of Human Genetics, School of Medicine, Emory University, Atlanta, GAUSAView further author information

Nastassja Koenf Neuroscience Institute, University of Cape Town, Cape Town, South Africa;g Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa;h South African Medical Research Council (SAMRC) Unit on Risk and Resilience in Mental Disorders, University of Cape Town, Cape Town, South AfricaView further author information

Michael P. Epsteine Department of Human Genetics, School of Medicine, Emory University, Atlanta, GAUSAView further author information

Michael S. Koborc Department of Medical Genetics, University of British Columbia, Vancouver, Canada;i BC Children’s Hospital Research Institute, Vancouver, Canada;j Centre for Molecular Medicine and Therapeutics, Vancouver, CanadaView further author information

Heather J. Zark Department of Pediatrics and Child Health, Red Cross War Memorial Children’s Hospital, University of Cape Town, Cape Town, South Africa;l South African Medical Research Council (SAMRC) Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South AfricaView further author information

Dan J. Steinf Neuroscience Institute, University of Cape Town, Cape Town, South Africa;g Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa;h South African Medical Research Council (SAMRC) Unit on Risk and Resilience in Mental Disorders, University of Cape Town, Cape Town, South AfricaView further author information

Anke Hülsa Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GAUSA;d Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GeorgiaCorrespondence[email protected]

https://orcid.org/0000-0002-6005-417X View further author information

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Pruning and thresholding approach for methylation risk scores in multi-ancestry populations

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