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Epigenetics
Volume 18, 2023 - Issue 1
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Research Article
Pruning and thresholding approach for methylation risk scores in multi-ancestry populations
Junyu Chena Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GAUSAView further author information
, Evan Gatevb Institute of Molecular Biology “Acad. Roumen Tsanev”, Sofia, Bulgaria;c Department of Medical Genetics, University of British Columbia, Vancouver, CanadaView further author information
, Todd Eversona Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GAUSA;d Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GeorgiaView further author information
, Karen N. Conneelye Department of Human Genetics, School of Medicine, Emory University, Atlanta, GAUSAView further author information
, Nastassja Koenf Neuroscience Institute, University of Cape Town, Cape Town, South Africa;g Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa;h South African Medical Research Council (SAMRC) Unit on Risk and Resilience in Mental Disorders, University of Cape Town, Cape Town, South AfricaView further author information
, Michael P. Epsteine Department of Human Genetics, School of Medicine, Emory University, Atlanta, GAUSAView further author information
, Michael S. Koborc Department of Medical Genetics, University of British Columbia, Vancouver, Canada;i BC Children’s Hospital Research Institute, Vancouver, Canada;j Centre for Molecular Medicine and Therapeutics, Vancouver, CanadaView further author information
, Heather J. Zark Department of Pediatrics and Child Health, Red Cross War Memorial Children’s Hospital, University of Cape Town, Cape Town, South Africa;l South African Medical Research Council (SAMRC) Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South AfricaView further author information
, Dan J. Steinf Neuroscience Institute, University of Cape Town, Cape Town, South Africa;g Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa;h South African Medical Research Council (SAMRC) Unit on Risk and Resilience in Mental Disorders, University of Cape Town, Cape Town, South AfricaView further author information
& Anke Hülsa Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GAUSA;d Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GeorgiaCorrespondence[email protected]
https://orcid.org/0000-0002-6005-417XView further author information
Article: 2187172
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Received 18 Oct 2022, Accepted 07 Feb 2023, Published online: 12 Mar 2023
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