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LETTER
Metal-free domino amination-Knoevenagel condensation approach to access new coumarins as potent nanomolar inhibitors of VEGFR-2 and EGFR
Essam M. Eliwaa Organic and Bioorganic Chemistry, Faculty of Chemistry, Bielefeld University, Bielefeld, Germany;b Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City-Cairo, EgyptCorrespondence[email protected] [email protected]
https://orcid.org/0000-0001-5570-1427View further author information
Marcel Fresea Organic and Bioorganic Chemistry, Faculty of Chemistry, Bielefeld University, Bielefeld, GermanyView further author information
, Ahmed H. Halawab Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City-Cairo, EgyptView further author information
, Maha M. Soltanc Biology Unit, Central Laboratory for Pharmaceutical and Drug Industries Research Division, Chemistry of Medicinal Plants Department, Pharmaceutical and Drug Industries Research Division, National Research CentreCairo, Egypt
https://orcid.org/0000-0002-7370-0142View further author information
Larissa V. Ponomarevad Center for Pharmaceutical Research and Innovation, University of Kentucky, Lexington, USA;e Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, USA
https://orcid.org/0000-0003-2182-8774View further author information
Jon S. Thorsond Center for Pharmaceutical Research and Innovation, University of Kentucky, Lexington, USA;e Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, USA
https://orcid.org/0000-0002-7148-0721View further author information
Khaled A. Shaaband Center for Pharmaceutical Research and Innovation, University of Kentucky, Lexington, USA;e Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, USA
https://orcid.org/0000-0001-7638-4942View further author information
Mohamed Shaabana Organic and Bioorganic Chemistry, Faculty of Chemistry, Bielefeld University, Bielefeld, Germany;f Chemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki-Cairo, Egypt
https://orcid.org/0000-0001-9281-2505View further author information
Ahmed M. El-Agrodyb Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City-Cairo, Egypt
https://orcid.org/0000-0001-7019-411XView further author information
Norbert Sewalda Organic and Bioorganic Chemistry, Faculty of Chemistry, Bielefeld University, Bielefeld, Germany
https://orcid.org/0000-0002-0309-2655View further author information
Pages 578-599
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Received 03 Jun 2021, Accepted 10 Sep 2021, Published online: 24 Sep 2021
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