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mAbs Volume 7, 2015 - Issue 6

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Stability engineering of anti-EGFR scFv antibodies by rational design of a lambda-to-kappa swap of the V_L framework using a structure-guided approach

Andreas LehmannMolecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA;Current address: Biogen, CambridgeMA

Josephine H F WixtedMolecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA

Maxim V ShapovalovMolecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA

Heinrich RoderMolecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA

Roland L Dunbrack Jr.Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PACorrespondence[email protected]

Matthew K RobinsonMolecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PACorrespondence[email protected]

Pages 1058-1071 | Received 17 Apr 2015, Accepted 26 Aug 2015, Published online: 25 Sep 2015

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https://doi.org/10.1080/19420862.2015.1088618
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