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Improved in vivo anti-tumor effects of IgA-Her2 antibodies through half-life extension and serum exposure enhancement by FcRn targeting
Saskia MeyerLaboratory of Translational Immunology; UMC Utrecht; Utrecht, The Netherlands
, Maaike NederendLaboratory of Translational Immunology; UMC Utrecht; Utrecht, The Netherlands
, J.H. Marco JansenLaboratory of Translational Immunology; UMC Utrecht; Utrecht, The Netherlands
, Karli R. ReidingCenter for Proteomics and Metabolomics; Leiden University Medical Center; Leiden, The Netherlands
, Shamir R. JacobinoLaboratory of Translational Immunology; UMC Utrecht; Utrecht, The Netherlands
, Jan MeeldijkLaboratory of Translational Immunology; UMC Utrecht; Utrecht, The Netherlands
, Niels BovenschenLaboratory of Translational Immunology; UMC Utrecht; Utrecht, The Netherlands;Department of Pathology; UMC Utrecht; Utrecht, The Netherlands
, Manfred WuhrerCenter for Proteomics and Metabolomics; Leiden University Medical Center; Leiden, The Netherlands
, Thomas ValeriusDivision of Stem Cell Transplantation and Immunotherapy; Department of Internal Medicine II; Christian-Albrechts-University; Kiel, Germany
, Ruud UbinkSynthon Biopharmaceuticals BV; Nijmegen, The Netherlands
, Peter BorossLaboratory of Translational Immunology; UMC Utrecht; Utrecht, The Netherlands
, Gerard RouwendalSynthon Biopharmaceuticals BV; Nijmegen, The Netherlands
& Jeanette H.W. LeusenLaboratory of Translational Immunology; UMC Utrecht; Utrecht, The NetherlandsCorrespondence[email protected]
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Pages 87-98
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Received 10 Jul 2015, Accepted 06 Oct 2015, Published online: 23 Nov 2015
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