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Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics
Pao-Chun LinBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore
, Kah Fai ChanBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore
, Irene A. KiessBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore
, Joselyn TanBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore
, Wahyu ShahreelBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore
, Sze-Yue WongBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore
& Zhiwei SongBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore;Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, SingaporeCorrespondence[email protected]
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Pages 965-976
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Received 29 Nov 2018, Accepted 22 Apr 2019, Published online: 04 Jun 2019
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