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Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis
Mingyan CaoDepartment of Analytical Sciences, MedImmune, Gaithersburg, MD, USA
https://orcid.org/0000-0001-5277-4962
Niluka De MelDepartment of Analytical Sciences, MedImmune, Gaithersburg, MD, USA
https://orcid.org/0000-0002-6394-5197
Yang JiaoDepartment of Analytical Sciences, MedImmune, Gaithersburg, MD, USA
, James HowardDepartment of Purification Process Sciences, MedImmune, Gaithersburg, MD, USA
https://orcid.org/0000-0003-3484-9451
Conner ParthemoreDepartment of Analytical Sciences, MedImmune, Gaithersburg, MD, USA
, Samuel KormanDepartment of Analytical Sciences, MedImmune, Gaithersburg, MD, USA
https://orcid.org/0000-0001-5946-887X
Christopher ThompsonDepartment of Purification Process Sciences, MedImmune, Gaithersburg, MD, USA
https://orcid.org/0000-0002-2163-9773
Michaela WendelerDepartment of Purification Process Sciences, MedImmune, Gaithersburg, MD, USA
https://orcid.org/0000-0001-7503-5257
Dengfeng LiuDepartment of Analytical Sciences, MedImmune, Gaithersburg, MD, USACorrespondence[email protected]
https://orcid.org/0000-0002-5816-4994
Pages 1064-1076
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Received 01 Mar 2019, Accepted 17 May 2019, Published online: 14 Jun 2019
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