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Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity
Raul C. Camachoa Janssen R&D, Spring House, PA, USACorrespondence[email protected]
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Seohee Youa Janssen R&D, Spring House, PA, USAView further author information
, Katharine E. D’Aquinoa Janssen R&D, Spring House, PA, USAView further author information
, Wenyu Lia Janssen R&D, Spring House, PA, USAView further author information
, Yuanping Wanga Janssen R&D, Spring House, PA, USAView further author information
, Joseph Gunneta Janssen R&D, Spring House, PA, USAView further author information
, James Littrella Janssen R&D, Spring House, PA, USAView further author information
, Jian Shen Qia Janssen R&D, Spring House, PA, USAView further author information
, Lijuan Kangb Pharmacokinetics, Dynamics, and Metabolism, Janssen R&D, Spring House, PA, USAView further author information
, Wenying Jianb Pharmacokinetics, Dynamics, and Metabolism, Janssen R&D, Spring House, PA, USAView further author information
, Mary MacDonaldc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Timothy Tatc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Derek Steinerc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Yue-Mei Zhanga Janssen R&D, Spring House, PA, USAView further author information
, James Lantera Janssen R&D, Spring House, PA, USAView further author information
, Raymond Patcha Janssen R&D, Spring House, PA, USAView further author information
, Rui Zhanga Janssen R&D, Spring House, PA, USAView further author information
, Jiali Lic Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Suzanne Edavettalc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Wilson Edwardsc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Thai Dinhc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Li Ying Wangc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Judy Connorc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Michael Hunterc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Ellen Chic Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, Ronald V. Swansonc Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
, James N. Leonarda Janssen R&D, Spring House, PA, USAView further author information
& Martin A. Casec Janssen Biotherapeutics, Janssen R&D, San Diego, La Jolla, CA, USAView further author information
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Article: 1794687
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Received 16 Apr 2020, Accepted 23 Jun 2020, Published online: 02 Aug 2020
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