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Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries
Michael R. Dysona IONTAS Ltd, Cambridge, UK
https://orcid.org/0000-0002-8382-0789
Edward Mastersa IONTAS Ltd, Cambridge, UK
, Deividas Pazeraitisa IONTAS Ltd, Cambridge, UK
, Rajika L. Pererab Poseidon Laboratory, Pasadena, CA, USA
https://orcid.org/0000-0002-4932-8168
Johanna L. Syrjanenc WM Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, NY, USA
https://orcid.org/0000-0002-6202-1881
Sachin Suradea IONTAS Ltd, Cambridge, UK
, Nels Thorsteinsond Chemical Computing Group ULC, Montreal, Quebec, Canada,
, Kothai Parthibana IONTAS Ltd, Cambridge, UK
, Philip C. Jonesa IONTAS Ltd, Cambridge, UK
, Maheen Sattara IONTAS Ltd, Cambridge, UK
, Gordana Wozniak-Knoppe Department of Biotechnology, BOKU-University of Natural Resources and Life Sciences, Vienna, Austria
, Florian Ruekere Department of Biotechnology, BOKU-University of Natural Resources and Life Sciences, Vienna, Austria
, Rachael Leaha IONTAS Ltd, Cambridge, UK
& John McCaffertya IONTAS Ltd, Cambridge, UKCorrespondence[email protected]
https://orcid.org/0000-0003-2195-0972
Article: 1829335
|
Received 09 Jun 2020, Accepted 17 Sep 2020, Published online: 25 Oct 2020
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