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mAbs Volume 13, 2021 - Issue 1
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Combining random mutagenesis, structure-guided design and next-generation sequencing to mitigate polyreactivity of an anti-IL-21R antibody

Sharon M. Campbella Biomedicine Design, Pfizer, Dublin, Ireland
,
Joseph DeBartolob Biomedicine Design, Pfizer, Cambridge, MA, USA
,
James R. Apgarb Biomedicine Design, Pfizer, Cambridge, MA, USA
,
Lydia Mosyakb Biomedicine Design, Pfizer, Cambridge, MA, USA
,
Virginie McManusa Biomedicine Design, Pfizer, Dublin, Ireland
,
Sonia Beyera Biomedicine Design, Pfizer, Dublin, Ireland
,
Eric M. Bennettb Biomedicine Design, Pfizer, Cambridge, MA, USA
,
Matthew Lamberta Biomedicine Design, Pfizer, Dublin, Ireland
&
Orla Cunninghama Biomedicine Design, Pfizer, Dublin, IrelandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3888-9541
ORCID Icon show all
Article: 1883239 | Received 02 Dec 2020, Accepted 26 Jan 2021, Published online: 09 Feb 2021

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