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mAbs Volume 15, 2023 - Issue 1
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Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies

Marissa Mocka Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0009-0009-0659-988XView further author information
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Alex W. Jacobitzb Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
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Christopher James Langmeada Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Athena Sudomc Structural Biology, Amgen Research, South San Francisco, CA, USAView further author information
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Daniel Yooa Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
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Sara C. Humphreysd Pharmacokinetics & Drug Metabolism, Amgen Research, South San Francisco, CA, USAView further author information
,
Mai Aldaya Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Larysa Alekseychykb Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
,
Nicolas Angellb Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
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Vivian Bia Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
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Hannah Catteralla Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
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Chen-Chun Chena Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Hui-Ting Chouc Structural Biology, Amgen Research, South San Francisco, CA, USAView further author information
,
Kip P. Connerd Pharmacokinetics & Drug Metabolism, Amgen Research, South San Francisco, CA, USAView further author information
,
Kevin D. Cookd Pharmacokinetics & Drug Metabolism, Amgen Research, South San Francisco, CA, USAView further author information
,
Ana R. Correiaa Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Andrew Dykstrab Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
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Sudipa Ghimire-Rijale Structural Biology, Amgen Research, Thousand Oaks, CA, USAView further author information
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Kevin Grahama Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
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Peter Grandsarda Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Joon Huhb Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
,
John O. Huia Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Mani Jaina Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Victoria Janna Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Lei Jiaa Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Sheree Johnstonec Structural Biology, Amgen Research, South San Francisco, CA, USAView further author information
,
Neelam Khanalb Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
,
Carl Kolvenbacha Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Linda Narhib Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
,
Rupa Padakib Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
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Emma M. Pelegri-O’Daya Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Wei Qib Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
,
Vladimir Razinkovb Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
,
Austin J. Ricea Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Richard Smithd Pharmacokinetics & Drug Metabolism, Amgen Research, South San Francisco, CA, USAView further author information
,
Christopher Spahra Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Jennitte Stevensb Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
,
Yax Suna Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Veena A. Thomasd Pharmacokinetics & Drug Metabolism, Amgen Research, South San Francisco, CA, USAView further author information
,
Sarah van Drieschea Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Robert Vernona Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Victoria Wagnera Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Kenneth W. Walkera Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Yangjie Weib Process Development, Amgen Operations, Thousand Oaks, CA, USAView further author information
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Dwight Wintersa Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
,
Melissa Yanga Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USAView further author information
&
Iain D. G. Campuzanoa Biologic Therapeutic Discovery, Amgen Research, Thousand Oaks, CA, USACorrespondence[email protected]
View further author information
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Article: 2256745 | Received 29 May 2023, Accepted 05 Sep 2023, Published online: 12 Sep 2023

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