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Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers
Ammelie Svea Bojea Division of Antibody-Based Immunotherapy, Department of Internal Medicine II, University Medical Center Schleswig-Holstein and University of Kiel, Kiel, GermanyView further author information
, Lukas Pekarb Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Katharina Koepc Drug Metabolism and Pharmacokinetics, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Britta Lipinskib Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Brian Rabinovichd Department of Oncology and Immuno-Oncology, EMD Serono Research & Development Institute Inc, 45A Middlesex Turnpike, Billerica, MA, USAView further author information
, Andreas Eversb Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Carina Lynn Gehlerta Division of Antibody-Based Immunotherapy, Department of Internal Medicine II, University Medical Center Schleswig-Holstein and University of Kiel, Kiel, GermanyView further author information
, Steffen Krohna Division of Antibody-Based Immunotherapy, Department of Internal Medicine II, University Medical Center Schleswig-Holstein and University of Kiel, Kiel, GermanyView further author information
, Yanping Xiaod Department of Oncology and Immuno-Oncology, EMD Serono Research & Development Institute Inc, 45A Middlesex Turnpike, Billerica, MA, USAView further author information
, Simon Krahb Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Rinat Zaynagetdinovd Department of Oncology and Immuno-Oncology, EMD Serono Research & Development Institute Inc, 45A Middlesex Turnpike, Billerica, MA, USAView further author information
, Lars Toleikise Early Protein Supply & Characterization, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Sven Poetzschf Strategic Innovation, Merck Healthcare KGaA, Darmstadt, GermanyView further author information
, Matthias Peippa Division of Antibody-Based Immunotherapy, Department of Internal Medicine II, University Medical Center Schleswig-Holstein and University of Kiel, Kiel, GermanyView further author information
, Stefan Zielonkab Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany;g Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, GermanyCorrespondence[email protected]
https://orcid.org/0000-0002-4649-2843View further author information
Katja Klausza Division of Antibody-Based Immunotherapy, Department of Internal Medicine II, University Medical Center Schleswig-Holstein and University of Kiel, Kiel, GermanyCorrespondence[email protected]
View further author information
show allView further author information
Article: 2315640
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Received 09 Jun 2023, Accepted 02 Feb 2024, Published online: 19 Feb 2024
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