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Journal of Extracellular Vesicles Volume 9, 2020 - Issue 1
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Research article

Fusion protein engineered exosomes for targeted degradation of specific RNAs in lysosomes: a proof-of-concept study

Zhelong Lia Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi’an, People’s Republic of China;b The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an, People’s Republic of ChinaView further author information
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Xueying Zhoua Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi’an, People’s Republic of China;b The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an, People’s Republic of ChinaView further author information
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Xiaotong Gaob The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an, People’s Republic of China;c Department of Hematology, Tangdu Hospital, Fourth Military Medical University, Xi’an, People’s Republic of ChinaView further author information
,
Danna Baid Department of Physiology, Fourth Military Medical University, Xi’an, People’s Republic of ChinaView further author information
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Yan Dongb The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an, People’s Republic of China;c Department of Hematology, Tangdu Hospital, Fourth Military Medical University, Xi’an, People’s Republic of ChinaView further author information
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Wenqi Suna Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi’an, People’s Republic of China;b The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an, People’s Republic of ChinaView further author information
,
Lianbi Zhaoa Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi’an, People’s Republic of China;b The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an, People’s Republic of ChinaView further author information
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Mengying Weib The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an, People’s Republic of ChinaView further author information
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Xuekang Yange Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, People’s Republic of ChinaCorrespondence[email protected]
View further author information
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Guodong Yangb The State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an, People’s Republic of ChinaCorrespondence[email protected]
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&
Lijun Yuana Department of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Xi’an, People’s Republic of ChinaCorrespondence[email protected]
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Article: 1816710 | Received 17 Dec 2019, Accepted 26 Aug 2020, Published online: 06 Sep 2020

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