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Research Article
The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway
Xuping Yanga Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;b Department of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Qinhui Liuc Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Yanping Lic Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Qin Tanga Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Tong Wua Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Lei Chena Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Shiyun Pua Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Yingnan Zhaoa Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Guorong Zhanga Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Cuiyuan Huanga Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Jinhang Zhanga Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Zijing Zhanga Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Ya Huanga Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaView further author information
, Min Zoua Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChinaView further author information
, Xiongjie Shid College of Life Sciences, the Institute for Advanced Studies, Wuhan University, Wuhan, ChinaView further author information
, Wei Jiange Molecular Medicine Research Center, West China Hospital of Sichuan University, Chengdu, ChinaView further author information
, Rui Wangf Department of Cardiology, Yangpu Hospital, Tongji University, Shanghai, ChinaCorrespondence[email protected]
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Jinhan Hea Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. ChengduChina;c Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ChengduChinaCorrespondence[email protected]
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Pages 484-494
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Received 25 Feb 2020, Accepted 22 Jul 2020, Published online: 23 Aug 2020
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