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OncoImmunology Volume 4, 2015 - Issue 4
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Original Research

Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice

Paulina PathriaInstitute for Cancer Research; Medical University Vienna & Comprehensive Cancer Center (CCC); Vienna, Austria
,
Dagmar GotthardtInstitute for Pharmacology and Toxicology; University of Veterinary MedicineVienna; Austria
,
Michaela Prchal-MurphyInstitute for Pharmacology and Toxicology; University of Veterinary MedicineVienna; Austria
,
Eva-Maria PutzInstitute for Pharmacology and Toxicology; University of Veterinary MedicineVienna; Austria
,
Martin HolcmannInstitute for Cancer Research; Medical University Vienna & Comprehensive Cancer Center (CCC); Vienna, Austria
,
Michaela SchledererLudwig Boltzmann Institute for Cancer Research LBICR; Vienna, Austria; Institute of Clinical Pathology; Medical University of Vienna; Vienna, Austria; Unit of Pathology of Laboratory Animals; University of Veterinary Medicine Vienna; Vienna, Austria
,
Beatrice GrabnerLudwig Boltzmann Institute for Cancer Research LBICR; Vienna, Austria; Institute of Clinical Pathology; Medical University of Vienna; Vienna, Austria; Unit of Pathology of Laboratory Animals; University of Veterinary Medicine Vienna; Vienna, Austria
,
Ilija CrncecInstitute for Cancer Research; Medical University Vienna & Comprehensive Cancer Center (CCC); Vienna, Austria
,
Jasmin SvinkaInstitute for Cancer Research; Medical University Vienna & Comprehensive Cancer Center (CCC); Vienna, Austria
,
Monica MusteanuSpanish National Cancer Research Centre (CNIO); Madrid, Spain
,
Thomas HoffmannInstitute of Molecular Pathology IMP; Vienna, Austria
,
Martin FilipitsInstitute for Cancer Research; Medical University Vienna & Comprehensive Cancer Center (CCC); Vienna, Austria
,
Walter BergerInstitute for Cancer Research; Medical University Vienna & Comprehensive Cancer Center (CCC); Vienna, Austria
,
Valeria PoliDepartment of Molecular Biotechnology and Health Sciences; Molecular Biotechnology Center; University of Turin; Italy
,
Lukas KennerLudwig Boltzmann Institute for Cancer Research LBICR; Vienna, Austria; Institute of Clinical Pathology; Medical University of Vienna; Vienna, Austria; Unit of Pathology of Laboratory Animals; University of Veterinary Medicine Vienna; Vienna, Austria
,
Martin BilbanMedical University Vienna; Department of Medical and Chemical Laboratory Diagnostics; Vienna, Austria;
,
Emilio CasanovaLudwig Boltzmann Institute for Cancer Research LBICR; Vienna, Austria; Institute of Clinical Pathology; Medical University of Vienna; Vienna, Austria; Unit of Pathology of Laboratory Animals; University of Veterinary Medicine Vienna; Vienna, Austria
,
Mathias MüllerInstitute of Animal Breeding and Genetics; University of Veterinary MedicineVienna; Vienna, Austria
,
Birgit StroblInstitute of Animal Breeding and Genetics; University of Veterinary MedicineVienna; Vienna, Austria
,
Editha BayerInstitute for Cancer Research; Medical University Vienna & Comprehensive Cancer Center (CCC); Vienna, Austria
,
Thomas MohrInstitute for Cancer Research; Medical University Vienna & Comprehensive Cancer Center (CCC); Vienna, Austria
,
Veronika SexlInstitute for Pharmacology and Toxicology; University of Veterinary MedicineVienna; Austria
&
Robert EferlInstitute for Cancer Research; Medical University Vienna & Comprehensive Cancer Center (CCC); Vienna, AustriaCorrespondence[email protected]
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Article: e998529 | Received 23 Oct 2014, Accepted 10 Dec 2014, Published online: 27 Apr 2015

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Platelets contribute to the initiation of colitis-associated cancer by promoting immunosuppression.
Source: Wiley

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