Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition

M. KuttkeInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, Austria

E. SahinInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, Austria

J. PisoniInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, Austria

S. PercigInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, Austria

A. VogelInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, Austria

D. KraemmerInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, Austria

L. HanzlInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, Austria

J. S. BrunnerInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, Austria

H. PaarInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, Austria

K. SoukupSt. Anna Children's Cancer Research Institute, Vienna, Austria

A. HalfmannSt. Anna Children's Cancer Research Institute, Vienna, Austria

A. M. DohnalSt. Anna Children's Cancer Research Institute, Vienna, Austria

C. W. SteinerDepartment of RheumatologyInternal Medicine III, Medical University of Vienna, Vienna, Austria

S. BlümlDepartment of RheumatologyInternal Medicine III, Medical University of Vienna, Vienna, Austria

J. BasilioInstitute for Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology Medical University of Vienna, Vienna, Austria

B. HochreiterInstitute for Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology Medical University of Vienna, Vienna, Austria

M. SalzmannInstitute for Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology Medical University of Vienna, Vienna, Austria

B. HoeselInstitute for Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology Medical University of Vienna, Vienna, Austria

G. LametschwandtnerApeiron Biologics AG, Vienna, Austria

R. EferlInstitute of Cancer Research, Internal Medicine I, Medical University of Vienna, Vienna, Austria

J. A. SchmidInstitute for Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology Medical University of Vienna, Vienna, Austria

G. SchabbauerInstitute for Physiology, Center for Physiology and Pharmacology, Medical University of ViennaVienna, AustriaCorrespondence[email protected]

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Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition

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Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition

KONI_A_1164918_s02.zip

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