Intratumoral expression levels of PD-L1, GZMA, and HLA-A along with oligoclonal T cell expansion associate with response to nivolumab in metastatic melanoma

Hiroyuki InoueDepartment of Medicine, The University of Chicago, Chicago, IL, USA

Jae-Hyun ParkDepartment of Medicine, The University of Chicago, Chicago, IL, USA

Kazuma KiyotaniDepartment of Medicine, The University of Chicago, Chicago, IL, USA

Makda ZewdeDepartment of Medicine, The University of Chicago, Chicago, IL, USA

Azusa MiyashitaDepartment of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Masatoshi JinninDepartment of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Yukiko KiniwaDepartment of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan

Ryuhei OkuyamaDepartment of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan

Ryota TanakaDepartment of Dermatology, Faculty of Medicine, The University of Tsukuba, Tsukuba, Japan

Yasuhiro FujisawaDepartment of Dermatology, Faculty of Medicine, The University of Tsukuba, Tsukuba, Japan

Hiroshi KatoDepartment of Geriatric and Environmental Dermatology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan

Akimichi MoritaDepartment of Geriatric and Environmental Dermatology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan

Jun AsaiDepartment of Dermatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan

Norito KatohDepartment of Dermatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan

Kenji YokotaDepartment of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan

Masashi AkiyamaDepartment of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan

Hironobu IhnDepartment of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Satoshi FukushimaDepartment of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, JapanCorrespondence[email protected]

, M.D., Ph.D. &

Yusuke NakamuraDepartment of Medicine, The University of Chicago, Chicago, IL, USACorrespondence[email protected]

, M.D., Ph.D. show all

Intratumoral expression levels of PD-L1, GZMA, and HLA-A along with oligoclonal T cell expansion associate with response to nivolumab in metastatic melanoma

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Intratumoral expression levels of PD-L1, GZMA, and HLA-A along with oligoclonal T cell expansion associate with response to nivolumab in metastatic melanoma

KONI_A_1204507_supplementary_data.docx

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