ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy

Seandean Lykke HarwoodImmunotherapy and Cell Engineering Laboratory, Department of Engineering, Aarhus University, Aarhus, Denmark

Ana Alvarez-CienfuegosDepartment of Antibody Engineering, Leadartis SL, Madrid, Spain

Natalia Nuñez-PradoImmunotherapy and Cell Engineering Laboratory, Department of Engineering, Aarhus University, Aarhus, Denmark

Marta CompteDepartment of Antibody Engineering, Leadartis SL, Madrid, Spain

Sara Hernández-PérezDepartment of Microbiology I (Immunology), School of Medicine, Universidad Complutense de Madrid, Madrid, Spain; Instituto de Investigación Sanitaria 12 de Octubre (imas12), Madrid, Spain

Nekane MerinoStructural Biology Unit, CIC bioGUNE, Parque Tecnológico de Bizkaia, Bizkaia, Derio, Spain

Jaume BonetLaboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Rocio NavarroMolecular Immunology Unit, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain

Paul M. P. Van Bergen en HenegouwenDivision of Cell Biology, Department of Biology, Science Faculty, Utrecht University, Utrecht, The Netherlands

http://orcid.org/0000-0001-6050-9042

Simon LykkemarkImmunotherapy and Cell Engineering Laboratory, Department of Engineering, Aarhus University, Aarhus, Denmark

Kasper MikkelsenImmunotherapy and Cell Engineering Laboratory, Department of Engineering, Aarhus University, Aarhus, Denmark

http://orcid.org/0000-0001-6062-4243

Kasper MølgaardImmunotherapy and Cell Engineering Laboratory, Department of Engineering, Aarhus University, Aarhus, Denmark

Frederic JabsImmunotherapy and Cell Engineering Laboratory, Department of Engineering, Aarhus University, Aarhus, Denmark

Laura SanzMolecular Immunology Unit, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain

Francisco J. BlancoStructural Biology Unit, CIC bioGUNE, Parque Tecnológico de Bizkaia, Bizkaia, Derio, Spain;IKERBASQUE, Basque Foundation for Science, Bizkaia, Bilbao, Spain

http://orcid.org/0000-0003-2545-4319

Pedro Roda-NavarroDepartment of Microbiology I (Immunology), School of Medicine, Universidad Complutense de Madrid, Madrid, Spain; Instituto de Investigación Sanitaria 12 de Octubre (imas12), Madrid, Spain

http://orcid.org/0000-0003-3799-8823

Luis Alvarez-VallinaImmunotherapy and Cell Engineering Laboratory, Department of Engineering, Aarhus University, Aarhus, DenmarkCorrespondence[email protected]

http://orcid.org/0000-0003-3053-6757

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ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy

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ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy

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