Supplemental material
OncoImmunology
Volume 8, 2019 - Issue 2
Original Research
Bortezomib sensitizes multiple myeloma to NK cells via ER-stress-induced suppression of HLA-E and upregulation of DR5
Mattias CarlstenLaboratory of Transplantation Immunotherapy, Hematology Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MDUSACorrespondence[email protected]
http://orcid.org/0000-0001-9815-0012View further author information
http://orcid.org/0000-0001-9815-0012View further author information, , , , , Cynthia St. HilaireLaboratory of Cardiovascular Regenerative Medicine, Center for Molecular Medicine, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MDUSAhttp://orcid.org/0000-0003-1871-6915View further author information
http://orcid.org/0000-0003-1871-6915View further author information & show allRelated Research Data
Implication of unfolded protein response in resveratrol-induced inhibition of K562 cell proliferation
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Elsevier BV
Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress
Source:
Springer Science and Business Media LLC
Selenite Induces Posttranscriptional Blockade of HLA-E Expression and Sensitizes Tumor Cells to CD94/NKG2A-Positive NK Cells
Source:
The American Association of Immunologists
A Phase I Trial of Adoptively Transferred Ex-Vivo Expanded Autologous Natural Killer (NK) Cells Following Treatment with Bortezomib to Sensitize Tumors to NK Cell Cytotoxicity
Source:
American Society of Hematology
Bortezomib and Depsipeptide Sensitize Tumors to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand: A Novel Method to Potentiate Natural Killer Cell Tumor Cytotoxicity
Source:
American Association for Cancer Research (AACR)
NK cell education: not an on-off switch but a tunable rheostat
Source:
Elsevier BV
Deficient expression of NCR in NK cells from acute myeloid leukemia: evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction
Source:
American Society of Hematology
Functions of natural killer cells
Source:
Springer Science and Business Media LLC
Methylseleninic acid and sodium selenite induce severe ER stress and subsequent apoptosis through UPR activation in PEL cells.
Source:
Elsevier BV
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.
Source:
Springer Science and Business Media LLC
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
Source:
Springer Science and Business Media LLC
Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells.
Source:
The American Association of Immunologists
Acquisition of a multidrug-resistant phenotype with a proteasome inhibitor in multiple myeloma
Source:
Springer Science and Business Media LLC
Bringing natural killer cells to the clinic: ex vivo manipulation
Source:
American Society of Hematology
Analysis of human lymphocyte antigen class I expression in gastric cancer by reverse transcriptase-polymerase chain reaction.
Source:
Elsevier BV
Bortezomib down-regulates the cell surface expression of HLA-class I and enhances natural killer cell-mediated lysis of myeloma
Source:
American Society of Hematology
Expression and Release of HLA-E by Melanoma Cells and Melanocytes: Potential Impact on the Response of Cytotoxic Effector Cells
Source:
HAL CCSD
Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells.
Source:
American Society of Hematology
Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition.
Source:
Oxford University Press (OUP)
The cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies
Source:
Springer Science and Business Media LLC
Proteasome inhibitor therapy in multiple myeloma
Source:
American Association for Cancer Research (AACR)
Inhibition of eIF2α Dephosphorylation Maximizes Bortezomib Efficiency and Eliminates Quiescent Multiple Myeloma Cells Surviving Proteasome Inhibitor Therapy
Source:
American Association for Cancer Research (AACR)
HLA-E upregulation on IFN-γ-activated AML blasts impairs CD94/NKG2A-dependent NK cytolysis after haplo-mismatched hematopoietic SCT
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Springer Science and Business Media LLC
Reduced DNAM-1 expression on bone marrow NK cells associated with impaired killing of CD34 + blasts in myelodysplastic syndrome
Source:
Springer Science and Business Media LLC
Self-consumption: the interplay of autophagy and apoptosis
Source:
Springer Science and Business Media LLC
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