Impaired autophagy by soluble endoglin, under physiological hypoxia in early pregnant period, is involved in poor placentation in preeclampsia

Akitoshi Nakashima Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama, Japan

Mikiko Yamanaka-Tatematsu Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama, Japan

Naonobu Fujita Department of Genetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

Keiichi Koizumi Division of Pathogenic Biochemistry, Institute of Natural Medicine, University of Toyama, Toyama, Japan

Tomoko Shima Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama, Japan

Toshiko Yoshida Department of Regenerative Medicine, University of Toyama, Toyama, Japan

Toshio Nikaido Department of Regenerative Medicine, University of Toyama, Toyama, Japan

Aikou Okamoto Department of Obstetrics and Gynecology, School of Medicine, The Jikei University, Tokyo, Japan

Tamotsu Yoshimori Department of Genetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

Shigeru Saito Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama, JapanCorrespondence[email protected]

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