A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling

Lucy Liu Molecular Medicine, Beckman Research Institute; City of Hope Comprehensive Cancer Center; Duarte, CA USA

Marina Kritsanida Pharmacognosy and Natural Products Chemistry; University of Athens; Athens, Greece

Prokopios Magiatis Pharmacognosy and Natural Products Chemistry; University of Athens; Athens, Greece

Nicolas Gaboriaud Pharmacognosy and Natural Products Chemistry; University of Athens; Athens, Greece

Yan Wang Molecular Medicine, Beckman Research Institute; City of Hope Comprehensive Cancer Center; Duarte, CA USA

Jun Wu Molecular Medicine, Beckman Research Institute; City of Hope Comprehensive Cancer Center; Duarte, CA USA

Ralf Buettner Molecular Medicine, Beckman Research Institute; City of Hope Comprehensive Cancer Center; Duarte, CA USA

Fan Yang Molecular Medicine, Beckman Research Institute; City of Hope Comprehensive Cancer Center; Duarte, CA USA

Sangkil Nam Molecular Medicine, Beckman Research Institute; City of Hope Comprehensive Cancer Center; Duarte, CA USA

Leandros Skaltsounis Pharmacognosy and Natural Products Chemistry; University of Athens; Athens, Greece

Richard Jove Molecular Medicine, Beckman Research Institute; City of Hope Comprehensive Cancer Center; Duarte, CA USACorrespondence[email protected]

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