The Prevention, Early Diagnosis and Treatment of Cervical Cancer

Created 07 May 2024 | 5 articles
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The morbidity and mortality of cervical cancer are fourth ranked in global female malignant tumors. It can be reduced significantly by implementing cytology and HPV testing effectively. The use of the HPV vaccine has also significantly reduced the incidence of human papillomavirus (HPV)-related diseases. Early diagnosis and treatment is the key to preventing cervical cancer, and can definitely reduce the incidence and mortality of cervical cancer. Cervical cancer is a preventable and curable disease, and HPV is a necessary but not sufficient cause of cervical cancer. Over the past few decades, the incidence and mortality of cervical cancer have decreased in most countries and regions, especially in developed countries. However, in developing countries and regions, cervical cancer morbidity and mortality remain high, which is closely related to the human development index, poverty rate, the coverage rate of cervical cancer screening, the sensitivity of cervical cytological testing, the accessibility of HPV vaccine, sexual lifestyle, and HPV virus transmission. In 2018, to reduce the global burden of cervical cancer, the WHO Director-General called for the elimination of cervical cancer worldwide (≤4 per 100,000 women worldwide). With the increasing coverage of cervical cancer screening and HPV vaccine, more and more HPV-independent cervical cancer is being identified. The questions of how to effectively achieve the goal of eliminating cervical cancer, how to effectively implement vaccination, early diagnosis and treatment, as well as the difficulties and challenges existing in practice, have been the concern of governments and medical institutions globally. We are calling for papers on cervical cancer (HPV dependent and HPV-independent) prevention, early diagnosis and treatment, including: • HPV vaccination • epidemiology of cervical cancer • risk factors • disparities and challenges • screening methods of cervical cancer • screening frequency and interval • screening outcomes and follow-up • screening in special populations • cost-effectiveness and implementation • the role of colposcopy in cervical cancer prevention and treatment • the treatment of cervical precancer. • innovative approaches to cervical cancer screening and prevention • clinicopathological and molecular characteristics of cervical precancer and cancer

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