Journal of Inflammation Research, Volume 13, Issue (2020)

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Journal of Inflammation Research, Volume 13, Issue (2020)

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Review

Review Article
Saturated Fatty Acids in Obesity-Associated Inflammation
Heping Zhou, CJ Urso & Viren Jadeja
Pages: 1-14
Published online: 06 Jan 2020
AbstractforSaturated Fatty Acids in Obesity-Associated Inflammation | Full Text | References | PDF (1.5 MB) | EPUB
  • 1050 Views
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Original Research

Article
The Association Between Inflammation, Epithelial Mesenchymal Transition and Stemness in Colorectal Carcinoma
Inese Briede, Ilze Strumfa, Andrejs Vanags & Janis Gardovskis
Pages: 15-34
Published online: 08 Jan 2020
AbstractforThe Association Between Inflammation, Epithelial Mesenchymal Transition and Stemness in Colorectal Carcinoma | Full Text | References | PDF (1.9 MB) | EPUB
  • 117 Views
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Open Access
Article
Human Monocytes/Macrophage Inflammatory Cytokine Changes Following in vivo and in vitro Schistomam manoni Infection
Mistire Wolde, Lisa C Laan, Girmay Medhin, Endalemaw Gadissa, Nega Berhe & Aster Tsegaye
Pages: 35-43
Published online: 16 Jan 2020
AbstractforHuman Monocytes/Macrophage Inflammatory Cytokine Changes Following in vivo and in vitro Schistomam manoni Infection | Full Text | References | PDF (4.4 MB) | EPUB
  • 93 Views
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Open Access
Article
Protective Effects of Curcumin and its Nano-Phytosome on Carrageenan-Induced Inflammation in Mice Model: Behavioral and Biochemical Responses
Saeideh Baradaran, Akbar Hajizadeh Moghaddam, Sedigheh Khanjani Jelodar & Nasroallah Moradi-kor
Pages: 45-51
Published online: 21 Jan 2020
AbstractforProtective Effects of Curcumin and its Nano-Phytosome on Carrageenan-Induced Inflammation in Mice Model: Behavioral and Biochemical Responses | Full Text | References | PDF (3.3 MB) | EPUB
  • 324 Views
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Review

Review Article
Clinical Evaluation of Risankizumab-rzaa in the Treatment of Plaque Psoriasis
Vidhatha Reddy, Eric J Yang, Bridget Myers & Wilson Liao
Pages: 53-60
Published online: 22 Jan 2020
AbstractforClinical Evaluation of Risankizumab-rzaa in the Treatment of Plaque Psoriasis | Full Text | References | PDF (506.3 KB) | EPUB
  • 248 Views
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Original Research

Article
Higher Dietary Inflammatory Index Scores are Associated with Increased Odds of Benign Breast Diseases in a Case–Control Study
Sama Aghababayan, Zahra Sheikhi Mobarakeh, Mostafa Qorbani, Zeinab Tiznobeyk, Azadeh Aminianfar & Gity Sotoudeh
Pages: 61-69
Published online: 05 Oct 2022
AbstractforHigher Dietary Inflammatory Index Scores are Associated with Increased Odds of Benign Breast Diseases in a Case–Control Study | Full Text | References | PDF (336.1 KB) | EPUB
  • 155 Views
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Open Access
Article
The Association Between Sortilin and Inflammation in Patients with Coronary Heart Disease
Wenxiu Han, Zhijie Wei, Hailiang Zhang, Chunmei Geng, Ruili Dang, Mengqi Yang, Jun Zhang, Changshui Wang & Pei Jiang
Pages: 71-79
Published online: 10 Feb 2020
AbstractforThe Association Between Sortilin and Inflammation in Patients with Coronary Heart Disease | Full Text | References | PDF (2.5 MB) | EPUB
  • 138 Views
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Article
Integrated Gene Expression Profiling Analysis Reveals Probable Molecular Mechanism and Candidate Biomarker in Anti-TNFα Non-Response IBD Patients
Yifan Liu, Yantao Duan & Yousheng Li
Pages: 81-95
Published online: 12 Feb 2020
AbstractforIntegrated Gene Expression Profiling Analysis Reveals Probable Molecular Mechanism and Candidate Biomarker in Anti-TNFα Non-Response IBD Patients | Full Text | References | PDF (8.4 MB) | EPUB
  • 140 Views
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Review

Review Article
Mitochondrial Dynamic Dysfunction as a Main Triggering Factor for Inflammation Associated Chronic Non-Communicable Diseases
Zeleke Geto, Meseret Derbew Molla, Feyissa Challa, Yohannes Belay & Tigist Getahun
Pages: 97-107
Published online: 14 Feb 2020
AbstractforMitochondrial Dynamic Dysfunction as a Main Triggering Factor for Inflammation Associated Chronic Non-Communicable Diseases | Full Text | References | PDF (3.9 MB) | EPUB
  • 358 Views
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Original Research

Article
Combination of Glutamine and Ulinastatin Treatments Greatly Improves Sepsis Outcomes
Junyan Wang, Jiahui Zhou & Shuancheng Bai
Pages: 109-115
Published online: 19 Feb 2020
AbstractforCombination of Glutamine and Ulinastatin Treatments Greatly Improves Sepsis Outcomes | Full Text | References | PDF (1 MB) | EPUB
  • 121 Views
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Article
Differential Immune Activating, Anti-Inflammatory, and Regenerative Properties of the Aqueous, Ethanol, and Solid Fractions of a Medicinal Mushroom Blend
Renee Davis, Alex Taylor, Regan Nally, Kathleen F Benson, Paul Stamets & Gitte S Jensen
Pages: 117-131
Published online: 05 Oct 2022
AbstractforDifferential Immune Activating, Anti-Inflammatory, and Regenerative Properties of the Aqueous, Ethanol, and Solid Fractions of a Medicinal Mushroom Blend | Full Text | References | PDF (12.2 MB) | EPUB
  • 302 Views
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Article
The Effect of Aqueous Extract of Trachyspermum ammi Seeds and Ibuprofen on Inflammatory Gene Expression in the Cartilage Tissue of Rats with Collagen-Induced Arthritis
Mohsen Korani & Mohammadnabi Jamshidi
Pages: 133-139
Published online: 28 Feb 2020
AbstractforThe Effect of Aqueous Extract of Trachyspermum ammi Seeds and Ibuprofen on Inflammatory Gene Expression in the Cartilage Tissue of Rats with Collagen-Induced Arthritis | Full Text | References | PDF (432.5 KB) | EPUB
  • 358 Views
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Review

Review Article
The Efficacy, Safety and Tolerability of Canakinumab in the Treatment of Familial Mediterranean Fever: A Systematic Review of the Literature
Mark Kacar, Sinisa Savic & Jeroen C H van der Hilst
Pages: 141-149
Published online: 05 Oct 2022
AbstractforThe Efficacy, Safety and Tolerability of Canakinumab in the Treatment of Familial Mediterranean Fever: A Systematic Review of the Literature | Full Text | References | PDF (477.2 KB) | EPUB
  • 167 Views
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Original Research

Article
Rituximab Prevents the Development of Experimental Autoimmune Encephalomyelitis (EAE): Comparison with Prophylactic, Therapeutic or Combinational Regimens
Mena R Al-ani, Tom K Raju, Mahmood Y Hachim, Ibrahim Y Hachim, Noha M Elemam, Maha Guimei, Riyad Bendardaf & Azzam A Maghazachi
Pages: 151-164
Published online: 10 Mar 2020
AbstractforRituximab Prevents the Development of Experimental Autoimmune Encephalomyelitis (EAE): Comparison with Prophylactic, Therapeutic or Combinational Regimens | Full Text | References | PDF (8 MB) | EPUB
  • 155 Views
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Open Access
Article
High-Intensity Interval Training Reversed High-Fat Diet–Induced M1-Macrophage Polarization in Rat Adipose Tissue via Inhibition of NOTCH Signaling
Mehrnoosh Shanaki, Maryam Khosravi, Arezoo Khoshdooni-Farahani, Alireza Dadashi, Mohammad Foad Heydari, Maryam Delfan, Hanieh Jafary & Sattar Gorgani-Firuzjaee
Pages: 165-174
Published online: 17 Mar 2020
AbstractforHigh-Intensity Interval Training Reversed High-Fat Diet–Induced M1-Macrophage Polarization in Rat Adipose Tissue via Inhibition of NOTCH Signaling | Full Text | References | PDF (3.2 MB) | EPUB
  • 1536 Views
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Article
Nicotine-Free e-Cigarette Vapor Exposure Stimulates IL6 and Mucin Production in Human Primary Small Airway Epithelial Cells
Shaan Gellatly, Nicole Pavelka, Taylor Crue, Kelly S Schweitzer, Brian J Day, Elysia Min, Mari Numata, Dennis R Voelker, April Scruggs, Irina Petrache & Hong Wei Chu
Pages: 175-185
Published online: 16 Apr 2020
AbstractforNicotine-Free e-Cigarette Vapor Exposure Stimulates IL6 and Mucin Production in Human Primary Small Airway Epithelial Cells | Full Text | References | PDF (1,000.3 KB) | EPUB
  • 221 Views
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Open Access
Article
Impact of Low Interferon-γ and IL-10 Levels on TNF-α and IL-6 Production by PHA-Induced PBMCs in Type 2 Diabetes Mellitus
Rona Kartika, Dyah Purnamasari, Saraswati Pradipta, Rahma A Larasati & Heri Wibowo
Pages: 187-193
Published online: 22 Apr 2020
AbstractforImpact of Low Interferon-γ and IL-10 Levels on TNF-α and IL-6 Production by PHA-Induced PBMCs in Type 2 Diabetes Mellitus | Full Text | References | PDF (1.7 MB) | EPUB
  • 256 Views
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Article
Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway
Dehua Liao, Yun Chen, Yujin Guo, Changshui Wang, Ni Liu, Qian Gong, Yingzhou Fu, Yilan Fu, Lizhi Cao, Dunwu Yao & Pei Jiang
Pages: 195-206
Published online: 12 May 2020
AbstractforSalvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway | Full Text | References | PDF (5.1 MB) | EPUB
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Corrigendum

Correction
General Theory of Inflammation: Patient Self-Administration of Hydrocortisone Safely Achieves Superior Control of Hydrocortisone-Responding Disorders by Matching Dosage with Symptom Intensity [Corrigendum]
Page: 207
Published online: 21 May 2020
CitationforGeneral Theory of Inflammation: Patient Self-Administration of Hydrocortisone Safely Achieves Superior Control of Hydrocortisone-Responding Disorders by Matching Dosage with Symptom Intensity [Corrigendum] | Full Text | PDF (153.6 KB) | EPUB
  • 57 Views
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Hypothesis

Discussion
“High Treg” Inflammations Promote (Most) Non-Hematologic Cancers While “Low Treg” Inflammations Promote Lymphoid Cancers
Zeev Elkoshi
Pages: 209-221
Published online: 21 May 2020
Abstractfor“High Treg” Inflammations Promote (Most) Non-Hematologic Cancers While “Low Treg” Inflammations Promote Lymphoid Cancers | Full Text | References | PDF (857.4 KB) | EPUB
  • 71 Views
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Original Research

Article
Serum Calprotectin, a Marker of Neutrophil Activation, and Other Mediators of Inflammation in Response to Various Types of Extreme Physical Exertion in Healthy Volunteers
Markus Niemelä, Onni Niemelä, Risto Bloigu, Aini Bloigu, Päivikki Kangastupa & Tatu Juvonen
Pages: 223-231
Published online: 05 Oct 2022
AbstractforSerum Calprotectin, a Marker of Neutrophil Activation, and Other Mediators of Inflammation in Response to Various Types of Extreme Physical Exertion in Healthy Volunteers | Full Text | References | PDF (657.5 KB) | EPUB
  • 139 Views
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Article
Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies
Renata Curciarello, Toni Sobande, Samantha Jones, Paolo Giuffrida, Antonio Di Sabatino, Guillermo H Docena, Thomas T MacDonald & Klaartje Kok
Pages: 233-243
Published online: 22 May 2020
AbstractforHuman Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies | Full Text | References | PDF (4.4 MB) | EPUB
  • 147 Views
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Review

Review Article
Antibiotics, Inflammation, and Preterm Labor: A Missed Conclusion
Sedigheh Hantoushzadeh, Roghayeh Anvari Aliabad & Amir Hossein Norooznezhad
Pages: 245-254
Published online: 25 May 2020
AbstractforAntibiotics, Inflammation, and Preterm Labor: A Missed Conclusion | Full Text | References | PDF (2.4 MB) | EPUB
  • 370 Views
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Commentary

Article Commentary
Hypercytokinemia and Pathogen–Host Interaction in COVID-19
Alaa Badawi
Pages: 255-261
Published online: 23 Jun 2020
AbstractforHypercytokinemia and Pathogen–Host Interaction in COVID-19 | Full Text | References | PDF (289.5 KB) | EPUB
  • 108 Views
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Original Research

Article
Defective Neutrophil Function in Patients with Sepsis Is Mostly Restored by ex vivo Ascorbate Incubation
Kritsanawan Sae-khow, Sasipha Tachaboon, Helen L Wright, Steven W Edwards, Nattachai Srisawat, Asada Leelahavanichkul & Direkrit Chiewchengchol
Pages: 263-274
Published online: 25 Jun 2020
AbstractforDefective Neutrophil Function in Patients with Sepsis Is Mostly Restored by ex vivo Ascorbate Incubation | Full Text | References | PDF (2.9 MB) | EPUB
  • 182 Views
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Review

Review Article
Periodontal Disease and Periodontal Disease-Related Bacteria Involved in the Pathogenesis of Alzheimer’s Disease
Kenji Matsushita, Masae Yamada-Furukawa, Mie Kurosawa & Yosuke Shikama
Pages: 275-283
Published online: 30 Jun 2020
AbstractforPeriodontal Disease and Periodontal Disease-Related Bacteria Involved in the Pathogenesis of Alzheimer’s Disease | Full Text | References | PDF (3.2 MB) | EPUB
  • 785 Views
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Original Research

Article
Alteration of Liver Biomarkers in Patients with SARS-CoV-2 (COVID-19)
Pourya Gholizadeh, Rohollah Safari, Parham Marofi, Elham Zeinalzadeh, Pasquale Pagliano, Khudaverdi Ganbarov, Silvano Esposito, Ehsaneh Khodadadi, Mehdi Yousefi & Hossein Samadi Kafil
Pages: 285-292
Published online: 01 Jul 2020
AbstractforAlteration of Liver Biomarkers in Patients with SARS-CoV-2 (COVID-19) | Full Text | References | PDF (2 MB) | EPUB
  • 256 Views
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Article
Mesenchymal Stem Cells Anti-Inflammatory Activity in Rats: Proinflammatory Cytokines
Nataliia Petryk & Oleksandr Shevchenko
Pages: 293-301
Published online: 05 Oct 2022
AbstractforMesenchymal Stem Cells Anti-Inflammatory Activity in Rats: Proinflammatory Cytokines | Full Text | References | PDF (2.6 MB) | EPUB
  • 234 Views
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Article
MicroRNA-21-3p Engineered Umbilical Cord Stem Cell-Derived Exosomes Inhibit Tendon Adhesion
Zhixiao Yao, Juehong Li, Xu Wang, Shiqiao Peng, Jiexin Ning, Yun Qian & Cunyi Fan
Pages: 303-316
Published online: 05 Oct 2022
AbstractforMicroRNA-21-3p Engineered Umbilical Cord Stem Cell-Derived Exosomes Inhibit Tendon Adhesion | Full Text | References | PDF (8.9 MB) | EPUB
  • 228 Views
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Article
The IL-33/sST2 Axis in Thromboangiitis Obliterans
Hiva Sharebiani, Mehran Mohareri, Ali Mirhosseini & Bahare Fazeli
Pages: 317-323
Published online: 05 Oct 2022
AbstractforThe IL-33/sST2 Axis in Thromboangiitis Obliterans | Full Text | References | PDF (2.3 MB) | EPUB
  • 104 Views
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Article
Pristimerin Inhibits MMP-9 Expression and Cell Migration Through Attenuating NOX/ROS-Dependent NF-κB Activation in Rat Brain Astrocytes Challenged with LPS
Chien-Chung Yang, Li-Der Hsiao, Hui-Ching Tseng, Ching-Ming Kuo & Chuen-Mao Yang
Pages: 325-341
Published online: 20 Jul 2020
AbstractforPristimerin Inhibits MMP-9 Expression and Cell Migration Through Attenuating NOX/ROS-Dependent NF-κB Activation in Rat Brain Astrocytes Challenged with LPS | Full Text | References | PDF (14 MB) | EPUB
  • 208 Views
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Article
Therapeutic Effect of C-C Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis
Suoyi Feng, Longzhu Ju, Ziqi Shao, Mark Grzanna, Lu Jia & Ming Liu
Pages: 343-356
Published online: 21 Jul 2020
AbstractforTherapeutic Effect of C-C Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis | Full Text | References | PDF (6.8 MB) | EPUB
  • 192 Views
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Open Access
Article
NOD1/2 and the C-Type Lectin Receptors Dectin-1 and Mincle Synergistically Enhance Proinflammatory Reactions Both In Vitro and In Vivo
Amir I Tukhvatulin, Alina S Dzharullaeva, Alina S Erokhova, Dmitry V Scheblyakov, Boris S Naroditsky, Alexander L Gintsburg & Denis Y Logunov
Pages: 357-368
Published online: 05 Oct 2022
AbstractforNOD1/2 and the C-Type Lectin Receptors Dectin-1 and Mincle Synergistically Enhance Proinflammatory Reactions Both In Vitro and In Vivo | Full Text | References | PDF (7.7 MB) | EPUB
  • 145 Views
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Article
The Anti-Inflammatory Effect of Pistacia Lentiscus in a Rat Model of Colitis
Maryam Ostovan, Seyyed Mohammad Bagher Fazljou, Hajar Khazraei, Mostafa Araj Khodaei & Mohammadli Torbati
Pages: 369-376
Published online: 22 Jul 2020
AbstractforThe Anti-Inflammatory Effect of Pistacia Lentiscus in a Rat Model of Colitis | Full Text | References | PDF (3.5 MB) | EPUB
  • 332 Views
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Article
NLRP3 Regulated CXCL12 Expression in Acute Neutrophilic Lung Injury
Yanwen Peng, Qiongli Wu, Hao Tang, Jingrou Chen, Qili Wu, Xiaofeng Yuan, Shiqiu Xiong, Yujin Ye & Haijin Lv
Pages: 377-386
Published online: 23 Jul 2020
AbstractforNLRP3 Regulated CXCL12 Expression in Acute Neutrophilic Lung Injury | Full Text | References | PDF (8.9 MB) | EPUB
  • 141 Views
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Article
Microbial Modulation of Coagulation Disorders in Venous Thromboembolism
Anna Lichota, Krzysztof Gwozdzinski & Eligia M Szewczyk
Pages: 387-400
Published online: 30 Jul 2020
AbstractforMicrobial Modulation of Coagulation Disorders in Venous Thromboembolism | Full Text | References | PDF (2.2 MB) | EPUB
  • 267 Views
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Article
CytokineExplore: An Online Tool for Statistical Analysis of Cytokine Concentration Datasets
Osama Kassem, Abdulwahab Al-Saleh, Fawaz Azizieh & Kamaludin Dingle
Pages: 401-410
Published online: 05 Oct 2022
AbstractforCytokineExplore: An Online Tool for Statistical Analysis of Cytokine Concentration Datasets | Full Text | References | PDF (1.6 MB) | EPUB
  • 232 Views
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Article
Protective Effects of Leukadherin1 in a Rat Model of Targeted Experimental Autoimmune Encephalomyelitis (EAE): Possible Role of P47phox and MDA Downregulation
Sara Hemmati, Mohammad Amin Sadeghi, Hasan Yousefi-Manesh, Mostafa Eslamiyeh, Ali Vafaei, Laleh Foroutani, Ghazaleh Donyadideh, AhmadReza Dehpour & Nima Rezaei
Pages: 411-420
Published online: 31 Jul 2020
AbstractforProtective Effects of Leukadherin1 in a Rat Model of Targeted Experimental Autoimmune Encephalomyelitis (EAE): Possible Role of P47phox and MDA Downregulation | Full Text | References | PDF (40.6 MB) | EPUB
  • 199 Views
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Review

Review Article
Modulation of Chronic Inflammation by Quercetin: The Beneficial Effects on Obesity
Shin Sato & Yuuka Mukai
Pages: 421-431
Published online: 04 Aug 2020
AbstractforModulation of Chronic Inflammation by Quercetin: The Beneficial Effects on Obesity | Full Text | References | PDF (1.8 MB) | EPUB
  • 931 Views
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Original Research

Article
Activity Disease in SLE Patients Affected IFN-γ in the IGRA Results
Winni Maharani, Dwi Febni Ratnaningsih, Fitria Utami, Fajar Awalia Yulianto, Anneke Dewina, Laniyati Hamijoyo & Nur Atik
Pages: 433-439
Published online: 14 Aug 2020
AbstractforActivity Disease in SLE Patients Affected IFN-γ in the IGRA Results | Full Text | References | PDF (639.2 KB) | EPUB
  • 198 Views
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Article
Peripheral Blood Inflammatory-Immune Cells as a Predictor of Infertility in Women with Polycystic Ovary Syndrome
ShuQiong He, XiaoDan Mao, HuiFang Lei, BinHua Dong, DanHua Guo, BeiHong Zheng & PengMing Sun
Pages: 441-450
Published online: 18 Aug 2020
AbstractforPeripheral Blood Inflammatory-Immune Cells as a Predictor of Infertility in Women with Polycystic Ovary Syndrome | Full Text | References | PDF (2.8 MB) | EPUB
  • 381 Views
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Review

Review Article
Recent Updates on Anti-Inflammatory and Antimicrobial Effects of Furan Natural Derivatives
Mohammad Alizadeh, Moludi Jalal, Khodaei Hamed, Amir Saber, Sorayya Kheirouri, Fatemeh Pourteymour Fard Tabrizi & Negin Kamari
Pages: 451-463
Published online: 19 Aug 2020
AbstractforRecent Updates on Anti-Inflammatory and Antimicrobial Effects of Furan Natural Derivatives | Full Text | References | PDF (2.4 MB) | EPUB
  • 946 Views
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Original Research

Article
Electro-Acupuncture on ST36 and SP6 Acupoints Ameliorates Lung Injury via Sciatic Nerve in a Rat Model of Limb Ischemia-Reperfusion
Wei Lin, Danyun Jia, Changchang Fu, Yihui Zheng & Zhenlang Lin
Pages: 465-470
Published online: 24 Aug 2020
AbstractforElectro-Acupuncture on ST36 and SP6 Acupoints Ameliorates Lung Injury via Sciatic Nerve in a Rat Model of Limb Ischemia-Reperfusion | Full Text | References | PDF (7.1 MB) | EPUB
  • 142 Views
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Case Report

Case Report
Immune-Mediated Necrotizing Myopathy Initially Presenting as Erythema Nodosum
Shuni Ying, Sheng Li, Shunli Tang, Qingmiao Sun, Deren Fang, Yali Li, Dingxian Zhu, Hong Fang & Jianjun Qiao
Pages: 471-476
Published online: 24 Aug 2020
AbstractforImmune-Mediated Necrotizing Myopathy Initially Presenting as Erythema Nodosum | Full Text | References | PDF (1.1 MB) | EPUB
  • 163 Views
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Original Research

Article
Comprehensive Evaluation of Lipopolysaccharide-Induced Changes in Rats Based on Metabolomics
Chunmei Geng, Yujin Guo, Changshui Wang, Changmeng Cui, Wenxiu Han, Dehua Liao & Pei Jiang
Pages: 477-486
Published online: 24 Aug 2020
AbstractforComprehensive Evaluation of Lipopolysaccharide-Induced Changes in Rats Based on Metabolomics | Full Text | References | PDF (4.8 MB) | EPUB
  • 198 Views
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Article
Comparative Effects of Dexamethasone and Meloxicam on Magnitude of the Acute Inflammatory Response Induced by Escherichia coli Lipopolysaccharide in Broiler Chickens
Mohadeseh Manzari Tavakoli, Bahman Abdi-Hachesoo, Saeed Nazifi, Najmeh Mosleh, Seyedeh Alemeh Hosseinian & Peyman Nakhaee
Pages: 487-495
Published online: 24 Aug 2020
AbstractforComparative Effects of Dexamethasone and Meloxicam on Magnitude of the Acute Inflammatory Response Induced by Escherichia coli Lipopolysaccharide in Broiler Chickens | Full Text | References | PDF (2.5 MB) | EPUB
  • 457 Views
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Article
Anti-Nociceptive and Anti-Inflammatory Activity of Hygrophila schulli Leaves
Gebretsadkan Hintsa Tekulu, Abrha Desta, Mebrahtom Gebrelibanos Hiben & Ephrem Mebrahtu Araya
Pages: 497-505
Published online: 04 Sep 2020
AbstractforAnti-Nociceptive and Anti-Inflammatory Activity of Hygrophila schulli Leaves | Full Text | References | PDF (926.5 KB) | EPUB
  • 175 Views
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Review

Review Article
Role of IFN and Complements System: Innate Immunity in SARS-CoV-2
Tewodros Shibabaw, Meseret Derbew Molla, Banchamlak Teferi & Birhanu Ayelign
Pages: 507-518
Published online: 09 Sep 2020
AbstractforRole of IFN and Complements System: Innate Immunity in SARS-CoV-2 | Full Text | References | PDF (3.8 MB) | EPUB
  • 271 Views
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Review Article
JAK Inhibitors in Rheumatoid Arthritis: An Evidence-Based Review on the Emerging Clinical Data
Robert Harrington, Shamma Ahmad Al Nokhatha & Richard Conway
Pages: 519-531
Published online: 14 Sep 2020
AbstractforJAK Inhibitors in Rheumatoid Arthritis: An Evidence-Based Review on the Emerging Clinical Data | Full Text | References | PDF (2.7 MB) | EPUB
  • 987 Views
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Original Research

Article
Pharmacological Inhibition of Galectin-3 Ameliorates Diabetes-Associated Cognitive Impairment, Oxidative Stress and Neuroinflammation in vivo and in vitro
Qingqing Yin, Jian Chen, Shizhan Ma, Chuanfang Dong, Yue Zhang, Xunyao Hou, Shangbin Li & Bin Liu
Pages: 533-542
Published online: 15 Sep 2020
AbstractforPharmacological Inhibition of Galectin-3 Ameliorates Diabetes-Associated Cognitive Impairment, Oxidative Stress and Neuroinflammation in vivo and in vitro | Full Text | References | PDF (3.3 MB) | EPUB
  • 220 Views
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Review

Review Article
Evolving Immunologic Perspectives in Chronic Inflammatory Demyelinating Polyneuropathy
Yusuf A Rajabally, Shahram Attarian & Emilien Delmont
Pages: 543-549
Published online: 16 Sep 2020
AbstractforEvolving Immunologic Perspectives in Chronic Inflammatory Demyelinating Polyneuropathy | Full Text | References | PDF (276.4 KB) | EPUB
  • 163 Views
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Review Article
Human Secretary Phospholipase A2 Mutations and Their Clinical Implications
Mohd Imran Khan & Gururao Hariprasad
Pages: 551-561
Published online: 16 Sep 2020
AbstractforHuman Secretary Phospholipase A2 Mutations and Their Clinical Implications | Full Text | References | PDF (1.1 MB) | EPUB
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Original Research

Article
Treatment of Recurrent Clostridioides difficile Infection Using Fecal Microbiota Transplantation in Iranian Patients with Underlying Inflammatory Bowel Disease
Masoumeh Azimirad, Abbas Yadegar, Fatemeh Gholami, Shabnam Shahrokh, Hamid Asadzadeh Aghdaei, Gianluca Ianiro, Hidekazu Suzuki, Giovanni Cammarota & Mohammad Reza Zali
Pages: 563-570
Published online: 05 Oct 2022
AbstractforTreatment of Recurrent Clostridioides difficile Infection Using Fecal Microbiota Transplantation in Iranian Patients with Underlying Inflammatory Bowel Disease | Full Text | References | PDF (298.1 KB) | EPUB
  • 143 Views
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Article
Spinal TLR4/P2X7 Receptor-Dependent NLRP3 Inflammasome Activation Contributes to the Development of Tolerance to Morphine-Induced Antinociception
Haiyan Wang, Yu Zhang, Xiaqing Ma, Wenying Wang, Xiaotao Xu, Min Huang, Liang Xu, Haibo Shi, Tifei Yuan, Wei Jiang, Aizhong Wang & Tao Xu
Pages: 571-582
Published online: 24 Sep 2020
AbstractforSpinal TLR4/P2X7 Receptor-Dependent NLRP3 Inflammasome Activation Contributes to the Development of Tolerance to Morphine-Induced Antinociception | Full Text | References | PDF (5.6 MB) | EPUB
  • 178 Views
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Article
Encephalitozoon cuniculi Genotype II Concentrates in Inflammation Foci
Klára Brdíčková, Bohumil Sak, Nikola Holubová, Dana Květoňová, Lenka Hlásková, Marta Kicia, Żaneta Kopacz & Martin Kváč
Pages: 583-593
Published online: 05 Oct 2022
AbstractforEncephalitozoon cuniculi Genotype II Concentrates in Inflammation Foci | Full Text | References | PDF (3.9 MB) | EPUB
  • 130 Views
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Article
Value of Platelet Distribution Width and Mean Platelet Volume in Disease Activity Score of Rheumatoid Arthritis
Safaa A A Khaled, Eman NasrEldin, Yasmine S Makarem & Hamdy F F Mahmoud
Pages: 595-606
Published online: 05 Oct 2022
AbstractforValue of Platelet Distribution Width and Mean Platelet Volume in Disease Activity Score of Rheumatoid Arthritis | Full Text | References | PDF (2.6 MB) | EPUB
  • 286 Views
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Review

Review Article
Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review
Yayun Xu & Feihu Chen
Pages: 607-617
Published online: 05 Oct 2022
AbstractforAntioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review | Full Text | References | PDF (3.3 MB) | EPUB
  • 396 Views
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Review Article
Targeting Chemokines and Chemokine Receptors in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
Sarah Dhaiban, Mena Al-Ani, Noha Mousaad Elemam & Azzam A Maghazachi
Pages: 619-633
Published online: 29 Sep 2020
AbstractforTargeting Chemokines and Chemokine Receptors in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis | Full Text | References | PDF (1.2 MB) | EPUB
  • 330 Views
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Original Research

Article
Long Non-Coding RNA H19 Participates in Periodontal Inflammation via Activation of Autophagy
Runzhi Guo, Yiping Huang, Hao Liu, Yunfei Zheng, Lingfei Jia & Weiran Li
Pages: 635-646
Published online: 30 Sep 2020
AbstractforLong Non-Coding RNA H19 Participates in Periodontal Inflammation via Activation of Autophagy | Full Text | References | PDF (6.7 MB) | EPUB
  • 131 Views
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Article
Evaluation of Analgesic and Anti-Inflammatory Activities of 80% Methanol Root Extract of Echinops kebericho M. (Asteraceae)
Tesfaye Yimer, Eshetie Melese Birru, Meaza Adugna, Mestayet Geta & Yohannes Kelifa Emiru
Pages: 647-658
Published online: 30 Sep 2020
AbstractforEvaluation of Analgesic and Anti-Inflammatory Activities of 80% Methanol Root Extract of Echinops kebericho M. (Asteraceae) | Full Text | References | PDF (386.9 KB) | EPUB
  • 857 Views
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Article
Creation of a Novel Inflammation-Based Score for Operable Colorectal Cancer Patients
Qian Huang, Yinghao Cao, Shouyi Wang & Rui Zhu
Pages: 659-671
Published online: 06 Oct 2020
AbstractforCreation of a Novel Inflammation-Based Score for Operable Colorectal Cancer Patients | Full Text | References | PDF (4.6 MB) | EPUB
  • 97 Views
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Review

Review Article
Inflammatory Cytokine: IL-17A Signaling Pathway in Patients Present with COVID-19 and Current Treatment Strategy
Tewodros Shibabaw
Pages: 673-680
Published online: 06 Oct 2020
AbstractforInflammatory Cytokine: IL-17A Signaling Pathway in Patients Present with COVID-19 and Current Treatment Strategy | Full Text | References | PDF (1.5 MB) | EPUB
  • 385 Views
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Original Research

Article
IgGs-Abzymes from the Sera of Patients with Systemic Lupus Erythematosus Hydrolyzed miRNAs
Evgeny A Ermakov, Evelina M Kabirova, Alexey E Sizikov, Valentina N Buneva & Georgy A Nevinsky
Pages: 681-699
Published online: 08 Oct 2020
AbstractforIgGs-Abzymes from the Sera of Patients with Systemic Lupus Erythematosus Hydrolyzed miRNAs | Full Text | References | PDF (11.5 MB) | EPUB
  • 138 Views
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Article
Overexpression of Aquaporin 1 in Synovium Aggravates Rat Collagen-Induced Arthritis Through Regulating β-Catenin Signaling: An in vivo and in vitro Study
Yu-rong Mu, Meng-yuan Zhou, Li Cai, Ming-ming Liu & Rong Li
Pages: 701-712
Published online: 08 Oct 2020
AbstractforOverexpression of Aquaporin 1 in Synovium Aggravates Rat Collagen-Induced Arthritis Through Regulating β-Catenin Signaling: An in vivo and in vitro Study | Full Text | References | PDF (6.5 MB) | EPUB
  • 146 Views
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Research Letter

Letter
The Role of Albumin/Globulin Ratio in Discharged COVID-19 Patients with Re-Positive Nucleic Acid Detection
Yu Hao, Ting Li, Chanfan Zheng & Shengwei Jin
Pages: 713-717
Published online: 12 Oct 2020
First Page PreviewforThe Role of Albumin/Globulin Ratio in Discharged COVID-19 Patients with Re-Positive Nucleic Acid Detection | Full Text | References | PDF (652.1 KB) | EPUB
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Original Research

Article
Pathogen-Associated Molecules from Gut Translocation Enhance Severity of Cecal Ligation and Puncture Sepsis in Iron-Overload β-Thalassemia Mice
Kritsanawan Sae-khow, Awirut Charoensappakit, Peerapat Visitchanakun, Wilasinee Saisorn, Saovaros Svasti, Suthat Fucharoen & Asada Leelahavanichkul
Pages: 719-735
Published online: 14 Oct 2020
AbstractforPathogen-Associated Molecules from Gut Translocation Enhance Severity of Cecal Ligation and Puncture Sepsis in Iron-Overload β-Thalassemia Mice | Full Text | References | PDF (14.2 MB) | EPUB
  • 189 Views
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Review

Review Article
Cytokine Response in SARS-CoV-2 Infection in the Elderly
Subuhi Sherwani & Mohd Wajid Ali Khan
Pages: 737-747
Published online: 20 Oct 2020
AbstractforCytokine Response in SARS-CoV-2 Infection in the Elderly | Full Text | References | PDF (1.3 MB) | EPUB
  • 154 Views
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Review Article
Role of Caspase-1 in the Pathogenesis of Inflammatory-Associated Chronic Noncommunicable Diseases
Meseret Derbew Molla, Yonas Akalu, Zeleke Geto, Baye Dagnew, Birhanu Ayelign & Tewodros Shibabaw
Pages: 749-764
Published online: 20 Oct 2020
AbstractforRole of Caspase-1 in the Pathogenesis of Inflammatory-Associated Chronic Noncommunicable Diseases | Full Text | References | PDF (1.7 MB) | EPUB
  • 201 Views
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Original Research

Article
Grewia mollis Leaf Extracts and Fractions Demonstrated Good Inhibitory Activity on Pro-Inflammatory Enzymes and with Lower Cytotoxicity in vitro
Isa I Adamu, Salmon A Adebayo & Mohammad S Al-Shahrani
Pages: 765-772
Published online: 23 Oct 2020
AbstractforGrewia mollis Leaf Extracts and Fractions Demonstrated Good Inhibitory Activity on Pro-Inflammatory Enzymes and with Lower Cytotoxicity in vitro | Full Text | References | PDF (1.7 MB) | EPUB
  • 151 Views
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Article
Selection of an Optimal Combination Panel to Better Triage COVID-19 Hospitalized Patients
Yueting Tang, Yirong Li, Jiayu Sun, Huaqin Pan, Fen Yao & Xiaoyang Jiao
Pages: 773-787
Published online: 05 Oct 2022
AbstractforSelection of an Optimal Combination Panel to Better Triage COVID-19 Hospitalized Patients | Full Text | References | PDF (3.5 MB) | EPUB
  • 120 Views
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Article
Serum and Urine Interleukin-6 and Interleukin-8 Levels Do Not Differentiate Acute Pyelonephritis from Lower Urinary Tract Infections in Children
Maysoun Al Rushood, Amal AL-Eisa & Rajaa’ AL-Attiyah
Pages: 789-797
Published online: 28 Oct 2020
AbstractforSerum and Urine Interleukin-6 and Interleukin-8 Levels Do Not Differentiate Acute Pyelonephritis from Lower Urinary Tract Infections in Children | Full Text | References | PDF (1.6 MB) | EPUB
  • 257 Views
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Article
Negative Correlation Between Vitamin A and Positive Correlation Between Vitamin E and Inflammation Among Healthy Adults in Korea: Based on the Korea National Health and Nutrition Examination Survey (KNHANES) 2016–2018 7th Edition
Ki-Hong Hong & Young Lee
Pages: 799-811
Published online: 29 Oct 2020
AbstractforNegative Correlation Between Vitamin A and Positive Correlation Between Vitamin E and Inflammation Among Healthy Adults in Korea: Based on the Korea National Health and Nutrition Examination Survey (KNHANES) 2016–2018 7th Edition | Full Text | References | PDF (2 MB) | EPUB
  • 183 Views
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Article
HPV-16 E2/E6 and POU5F1B as Biomarkers to Determine Cervical High-Grade Squamous Lesions and More
Lihua Chen, Binhua Dong, Hangjing Gao, Huifeng Xue, Diling Pan & Pengming Sun
Pages: 813-821
Published online: 29 Oct 2020
AbstractforHPV-16 E2/E6 and POU5F1B as Biomarkers to Determine Cervical High-Grade Squamous Lesions and More | Full Text | References | PDF (2.1 MB) | EPUB
  • 144 Views
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Review

Review Article
Coagulation Disorders in COVID-19: Role of Toll-like Receptors
Indranil Biswas & Gausal A Khan
Pages: 823-828
Published online: 05 Oct 2022
AbstractforCoagulation Disorders in COVID-19: Role of Toll-like Receptors | Full Text | References | PDF (690.7 KB) | EPUB
  • 208 Views
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Original Research

Article
Active Cousinia thomsonii Extracts Modulate Expression of Crucial Proinflammatory Mediators/Cytokines and NFκB Cascade in Lipopolysaccharide-Induced Albino Wistar Rat Model
Khalid Bashir Dar, Ishfaq Shafi Khan, Shajrul Amin, Aijaz Hassan Ganie, Aashiq Hussain Bhat, Showkat Ahmad Dar, Bilal Ahmad Reshi & Showkat Ahmad Ganie
Pages: 829-845
Published online: 02 Nov 2020
AbstractforActive Cousinia thomsonii Extracts Modulate Expression of Crucial Proinflammatory Mediators/Cytokines and NFκB Cascade in Lipopolysaccharide-Induced Albino Wistar Rat Model | Full Text | References | PDF (7.1 MB) | EPUB
  • 196 Views
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Article
Mangiferin Inhibits Apoptosis and Autophagy Induced by Staphylococcus aureus in RAW264.7 Cells
Jun Xu, Hua Yao, Shichen Wang, Huanrong Li & Xiaolin Hou
Pages: 847-857
Published online: 03 Nov 2020
AbstractforMangiferin Inhibits Apoptosis and Autophagy Induced by Staphylococcus aureus in RAW264.7 Cells | Full Text | References | PDF (7.3 MB) | EPUB
  • 205 Views
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Review

Review Article
Which idea is better with regard to immune response? Opioid anesthesia or opioid free anesthesia
Barbara Lisowska, Jakub Jakubiak, Katarzyna Siewruk, Maria Sady & Dariusz Kosson
Pages: 859-869
Published online: 05 Nov 2020
AbstractforWhich idea is better with regard to immune response? Opioid anesthesia or opioid free anesthesia | Full Text | References | PDF (337 KB) | EPUB
  • 324 Views
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Original Research

Article
Acute Changes in Interleukin-6 Level During Four Days of Long-Distance Walking
Viviane Soares, Ivan Silveira de Avelar, Patrícia Espíndola Mota Venâncio, Deise A A Pires-Oliveira, Pedro Henrique de Almeida Silva, Amanda Rodrigues Borges, Gustavo Paz Estevez Ferreira Fonseca & Matias Noll
Pages: 871-878
Published online: 10 Nov 2020
AbstractforAcute Changes in Interleukin-6 Level During Four Days of Long-Distance Walking | Full Text | References | PDF (1.3 MB) | EPUB
  • 155 Views
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Perspectives

Discussion
The Inflammatory Aspect of Male and Female Pattern Hair Loss
Nadia Peyravian, Sapna Deo, Sylvia Daunert & Joaquin J Jimenez
Pages: 879-881
Published online: 10 Nov 2020
AbstractforThe Inflammatory Aspect of Male and Female Pattern Hair Loss | Full Text | References | PDF (226.1 KB) | EPUB
  • 571 Views
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Original Research

Article
Sinapic Acid Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration
Jin-Feng Huang, Xuan-Qi Zheng, Jia-Liang Lin, Kai Zhang, Hai-Jun Tian, Wen-Xian Zhou, Hui Wang, Ze Gao, Hai-Ming Jin & Ai-Min Wu
Pages: 883-895
Published online: 05 Oct 2022
AbstractforSinapic Acid Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration | Full Text | References | PDF (7.3 MB) | EPUB
  • 195 Views
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Article
Multiple Components Rapidly Screened from Perilla Leaves Attenuate Asthma Airway Inflammation by Synergistic Targeting on Syk
Hui Yang, Wei Sun, Pei Ma, Chunsuo Yao, Yannan Fan, Shuyi Li, Jiqiao Yuan, Ziqian Zhang, Xuyu Li, Mingbao Lin & Qi Hou
Pages: 897-911
Published online: 13 Nov 2020
AbstractforMultiple Components Rapidly Screened from Perilla Leaves Attenuate Asthma Airway Inflammation by Synergistic Targeting on Syk | Full Text | References | PDF (9.8 MB) | EPUB
  • 153 Views
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Review

Review Article
Inflammation, Bone Healing and Osteonecrosis: From Bedside to Bench
Stuart B Goodman & Masahiro Maruyama
Pages: 913-923
Published online: 13 Nov 2020
AbstractforInflammation, Bone Healing and Osteonecrosis: From Bedside to Bench | Full Text | References | PDF (2.5 MB) | EPUB
  • 271 Views
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Original Research

Article
Human Lung Macrophages Challenged to Oxidants ex vivo: Lysosomal Membrane Sensitization is Associated with Inflammation and Chronic Airflow Limitation
Hans Lennart Persson, Apostolos Sioutas, Petra Jacobson & Linda K Vainikka
Pages: 925-932
Published online: 16 Nov 2020
AbstractforHuman Lung Macrophages Challenged to Oxidants ex vivo: Lysosomal Membrane Sensitization is Associated with Inflammation and Chronic Airflow Limitation | Full Text | References | PDF (911.5 KB) | EPUB
  • 94 Views
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Article
Prognostic Value of Gastrokine-2 (GKN2) and Its Correlation with Tumor-Infiltrating Immune Cells in Lung Cancer and Gastric Cancers
Fangteng Liu & Hengyu Wu
Pages: 933-944
Published online: 16 Nov 2020
AbstractforPrognostic Value of Gastrokine-2 (GKN2) and Its Correlation with Tumor-Infiltrating Immune Cells in Lung Cancer and Gastric Cancers | Full Text | References | PDF (11.8 MB) | EPUB
  • 101 Views
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Article
Galangin Inhibits LPS-Induced MMP-9 Expression via Suppressing Protein Kinase-Dependent AP-1 and FoxO1 Activation in Rat Brain Astrocytes
Chien-Chung Yang, Li-Der Hsiao & Chuen-Mao Yang
Pages: 945-960
Published online: 20 Nov 2020
AbstractforGalangin Inhibits LPS-Induced MMP-9 Expression via Suppressing Protein Kinase-Dependent AP-1 and FoxO1 Activation in Rat Brain Astrocytes | Full Text | References | PDF (9.8 MB) | EPUB
  • 194 Views
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Review

Review Article
Lymphatic Flow: A Potential Target in Sepsis-Associated Acute Lung Injury
Chenghua Wu, Hui Li, Puhong Zhang, Chao Tian, Jun Luo, Wenyan Zhang, Suwas Bhandari, Shengwei Jin & Yu Hao
Pages: 961-968
Published online: 23 Nov 2020
AbstractforLymphatic Flow: A Potential Target in Sepsis-Associated Acute Lung Injury | Full Text | References | PDF (1.2 MB) | EPUB
  • 204 Views
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Original Research

Article
Clusterin Deficiency Predisposes C57BL/6j Mice to Cationic Bovine Serum Albumin-Induced Glomerular Inflammation
Pengcheng Sun, Shijian Feng, Qiunong Guan, Hans Adomat, Sean Barbour, Martin E Gleave, Christopher Y C Nguan, Wanhai Xu & Caigan Du
Pages: 969-983
Published online: 24 Nov 2020
AbstractforClusterin Deficiency Predisposes C57BL/6j Mice to Cationic Bovine Serum Albumin-Induced Glomerular Inflammation | Full Text | References | PDF (6.3 MB) | EPUB
  • 165 Views
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Article
Immunological Evaluation on Potential Treatment Window for Hospitalized COVID-19 Patients
Jing Yuan, Shanglong Kou, Yanhua Liang, JianFeng Lan, Xiaohe Li, Lijiao Zeng, Rongrong Zou, Yingxia Liu, Lei Liu & Yanchao Pan
Pages: 985-993
Published online: 24 Nov 2020
AbstractforImmunological Evaluation on Potential Treatment Window for Hospitalized COVID-19 Patients | Full Text | References | PDF (2.8 MB) | EPUB
  • 87 Views
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Article
Enhancement of Circulating and Intestinal T Regulatory Cells and Their Expression of Helios and Neuropilin-1 in Children with Inflammatory Bowel Disease
Katarzyna Sznurkowska, Justyna Luty, Ewa Bryl, Jacek M Witkowski, Blanka Hermann-Okoniewska, Piotr Landowski, Marta Kosek & Agnieszka Szlagatys-Sidorkiewicz
Pages: 995-1005
Published online: 26 Nov 2020
AbstractforEnhancement of Circulating and Intestinal T Regulatory Cells and Their Expression of Helios and Neuropilin-1 in Children with Inflammatory Bowel Disease | Full Text | References | PDF (5.1 MB) | EPUB
  • 164 Views
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Article
MicroRNA-21 Mediates a Positive Feedback on Angiotensin II-Induced Myofibroblast Transformation
Dongjiu Li, Chengyu Mao, En Zhou, Jiayin You, Erhe Gao, Zhihua Han, Yuqi Fan, Qing He & Changqian Wang
Pages: 1007-1020
Published online: 27 Nov 2020
AbstractforMicroRNA-21 Mediates a Positive Feedback on Angiotensin II-Induced Myofibroblast Transformation | Full Text | References | PDF (9.2 MB) | EPUB
  • 135 Views
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Clinical Trial Report

Case Report
Plasma Acute Phase Proteins as Predictors of Chronic Lung Allograft Dysfunction in Lung Transplant Recipients
Sabina Janciauskiene, Pierre-Joseph Royer, Jan Fuge, Sabine Wrenger, Joanna Chorostowska-Wynimko, Christine Falk, Tobias Welte, Martine Reynaud-Gaubert, Antoine Roux, Adrien Tissot & Antoine Magnan
Pages: 1021-1028
Published online: 30 Nov 2020
AbstractforPlasma Acute Phase Proteins as Predictors of Chronic Lung Allograft Dysfunction in Lung Transplant Recipients | Full Text | References | PDF (1.8 MB) | EPUB
  • 111 Views
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Original Research

Article
Identification of Key Genes Associated with Changes in the Host Response to Severe Burn Shock: A Bioinformatics Analysis with Data from the Gene Expression Omnibus (GEO) Database
Xiao Fang, Shu-Fang Duan, Yu-Zhou Gong, Fei Wang & Xu-Lin Chen
Pages: 1029-1041
Published online: 01 Dec 2020
AbstractforIdentification of Key Genes Associated with Changes in the Host Response to Severe Burn Shock: A Bioinformatics Analysis with Data from the Gene Expression Omnibus (GEO) Database | Full Text | References | PDF (5.6 MB) | EPUB
  • 444 Views
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Article
Celecoxib Exerts a Therapeutic Effect Against Demyelination by Improving the Immune and Inflammatory Microenvironments
Peipei Cao, Hao Zhang, Huiling Meng, Yajia Cheng, Haiqi Xu, Siwen Zang, Zongjin Li, Jianlin Cui & Yuhao Li
Pages: 1043-1055
Published online: 01 Dec 2020
AbstractforCelecoxib Exerts a Therapeutic Effect Against Demyelination by Improving the Immune and Inflammatory Microenvironments | Full Text | References | PDF (7.1 MB) | EPUB
  • 164 Views
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Review

Review Article
Reactive Oxygen Species: Drivers of Physiological and Pathological Processes
Javier Checa & Josep M Aran
Pages: 1057-1073
Published online: 02 Dec 2020
AbstractforReactive Oxygen Species: Drivers of Physiological and Pathological Processes | Full Text | References | PDF (5.1 MB) | EPUB
  • 2167 Views
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Original Research

Article
Diallyl Sulfide-Mediated Modulation of the Fatty Acid Synthase (FASN) Leads to Cancer Cell Death in BaP-Induced Lung Carcinogenesis in Swiss Mice
Arif Khan, Fahad A Alhumaydhi, Ameen S S Alwashmi, Khaled S Allemailem, Mohammed A Alsahli, Faris A Alrumaihi, Ahmad Almatroudi, Mugahid A Mobark, Ayman Mousa & Masood A Khan
Pages: 1075-1087
Published online: 08 Dec 2020
AbstractforDiallyl Sulfide-Mediated Modulation of the Fatty Acid Synthase (FASN) Leads to Cancer Cell Death in BaP-Induced Lung Carcinogenesis in Swiss Mice | Full Text | References | PDF (8.1 MB) | EPUB
  • 160 Views
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Article
Clinical Value of SARS-CoV2 IgM and IgG Antibodies in Diagnosis of COVID-19 in Suspected Cases
Yangchun Feng
Pages: 1089-1094
Published online: 10 Dec 2020
AbstractforClinical Value of SARS-CoV2 IgM and IgG Antibodies in Diagnosis of COVID-19 in Suspected Cases | Full Text | References | PDF (992.1 KB) | EPUB
  • 99 Views
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Article
LncRNA SOX2OT rs9839776 Polymorphism Reduces Sepsis Susceptibility in Southern Chinese Children
Zhiyuan Wu, Yongqin Yu, Lanyan Fu, Hanran Mai, Li Huang, Di Che, Jianping Tao & Xiaoqiong Gu
Pages: 1095-1101
Published online: 10 Dec 2020
AbstractforLncRNA SOX2OT rs9839776 Polymorphism Reduces Sepsis Susceptibility in Southern Chinese Children | Full Text | References | PDF (381.4 KB) | EPUB
  • 104 Views
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Article
Association of Plasminogen Activator Inhibitor 1 (PAI-1) 4G/5G Polymorphism and Susceptibility to SLE in Egyptian Children and Adolescents: A Multicenter Study
Aly A Yousef, Faisal Y Mohamed, Naglaa F Boraey, Nagwa E Akeel, Attia A Soliman, Nevin M Waked, Mustafa I A Hashem, Hassan Shehata, Dalia S Fahmy, Ali Ismael, Lamya M Ibrahim, Mohamed A M Ibrahim, Hanan F Salem, Sherif M Yousry, Sherif F Osman, Rania A Fouad, Eman T Enan, Mohammed A Attia, Mona R Afify, Nancy M S Zeidan & Mohamed Nashat
Pages: 1103-1111
Published online: 14 Dec 2020
AbstractforAssociation of Plasminogen Activator Inhibitor 1 (PAI-1) 4G/5G Polymorphism and Susceptibility to SLE in Egyptian Children and Adolescents: A Multicenter Study | Full Text | References | PDF (2.1 MB) | EPUB
  • 287 Views
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Article
Circulating Neutrophil-Derived Microparticles Associated with the Prognosis of Patients with Sepsis
Hong-Peng Chen, Xiao-Yan Wang, Xiao-Yan Pan, Wang-Wang Hu, Shu-Ting Cai, Kiran Joshi, Lie-Hua Deng & Daqing Ma
Pages: 1113-1124
Published online: 14 Dec 2020
AbstractforCirculating Neutrophil-Derived Microparticles Associated with the Prognosis of Patients with Sepsis | Full Text | References | PDF (5.4 MB) | EPUB
  • 154 Views
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Article
Structural Modeling of Wild and Mutant Forms of Human Plasma Platelet Activating Factor-Acetyl Hydrolase Enzyme
Mohd Imran Khan & Gururao Hariprasad
Pages: 1125-1139
Published online: 16 Dec 2020
AbstractforStructural Modeling of Wild and Mutant Forms of Human Plasma Platelet Activating Factor-Acetyl Hydrolase Enzyme | Full Text | References | PDF (9.1 MB) | EPUB
  • 147 Views
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Article
Methotrexate (MTX) Plus Hydroxychloroquine versus MTX Plus Leflunomide in Patients with MTX-Resistant Active Rheumatoid Arthritis: A 2-Year Cohort Study in Real World
Le Zhang, Fangfang Chen, Shikai Geng, Xiaodong Wang, Liyang Gu, Yitian Lang, Ting Li & Shuang Ye
Pages: 1141-1150
Published online: 18 Dec 2020
AbstractforMethotrexate (MTX) Plus Hydroxychloroquine versus MTX Plus Leflunomide in Patients with MTX-Resistant Active Rheumatoid Arthritis: A 2-Year Cohort Study in Real World | Full Text | References | PDF (2.2 MB) | EPUB
  • 247 Views
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Article
Association of Diabetes and Admission Blood Glucose Levels with Short-Term Outcomes in Patients with Critical Illnesses
Shan Lin, Wanmei He & Mian Zeng
Pages: 1151-1166
Published online: 22 Dec 2020
AbstractforAssociation of Diabetes and Admission Blood Glucose Levels with Short-Term Outcomes in Patients with Critical Illnesses | Full Text | References | PDF (5.8 MB) | EPUB
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Article
Inflammatory Subtypes in Classic Asthma and Cough Variant Asthma
Jie Gao, Feng Wu, Sifang Wu & Xing Yang
Pages: 1167-1173
Published online: 22 Dec 2020
AbstractforInflammatory Subtypes in Classic Asthma and Cough Variant Asthma | Full Text | References | PDF (1.2 MB) | EPUB
  • 237 Views
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Evaluation of Analgesic and Anti-inflammatory Potential of 80% Methanol Leaf Extract of Otostegia integrifolia Benth (Lamiaceae)
Rediet Tesfaye, Abel Degu, Besufekad Abebe & Hiwot Ayalew
Pages: 1175-1183
Published online: 23 Dec 2020
AbstractforEvaluation of Analgesic and Anti-inflammatory Potential of 80% Methanol Leaf Extract of Otostegia integrifolia Benth (Lamiaceae) | Full Text | References | PDF (422 KB) | EPUB
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RETRACTED ARTICLE: Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats
Zikra Zulfiqar, Fawad Ali Shah, Shagufta Shafique, Abdullah Alattar, Tahir Ali, Arooj Mohsin Alvi, Sajid Rashid & Shupeng Li
Pages: 1185-1205
Published online: 24 Dec 2020
AbstractforRETRACTED ARTICLE: Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats | PDF (14.5 MB)
  • 175 Views
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Relationships Between Vitamin D Status and Cytokine: Results from Interferon-Based Therapy in Non-Cirrhotic, Treatment-Naïve Patients with Chronic Hepatitis C Infection
Hsuan-Wei Chen, Yi-Lin Chiu, Tsai-Yuan Hsieh, Peng-Jen Chen, Tien-Yu Huang, Hsuan-Hwai Lin, Yu-Lueng Shih & Jung-Chun Lin
Pages: 1207-1218
Published online: 29 Dec 2020
AbstractforRelationships Between Vitamin D Status and Cytokine: Results from Interferon-Based Therapy in Non-Cirrhotic, Treatment-Naïve Patients with Chronic Hepatitis C Infection | Full Text | References | PDF (5.6 MB) | EPUB
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Calcio-Herbal Medicine Divya-Swasari-Vati Ameliorates SARS-CoV-2 Spike Protein-Induced Pathological Features and Inflammation in Humanized Zebrafish Model by Moderating IL-6 and TNF-α Cytokines
Acharya Balkrishna, Sudeep Verma, Siva Kumar Solleti, Lakshmipathi Khandrika & Anurag Varshney
Pages: 1219-1243
Published online: 05 Oct 2022
AbstractforCalcio-Herbal Medicine Divya-Swasari-Vati Ameliorates SARS-CoV-2 Spike Protein-Induced Pathological Features and Inflammation in Humanized Zebrafish Model by Moderating IL-6 and TNF-α Cytokines | Full Text | References | PDF (12 MB) | EPUB
  • 224 Views
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Article
The Prognostic Significance of 5-Fluorouracil Induced Inflammation and Immuno-Modulation in Colorectal Cancer Patients
Mona S Abdellateif, Salem E Salem, Doaa M Badr, Sabry Shaarawy, Marwa M Hussein, Abdel-Rahman N Zekri & Mariam A Fouad
Pages: 1245-1259
Published online: 31 Dec 2020
AbstractforThe Prognostic Significance of 5-Fluorouracil Induced Inflammation and Immuno-Modulation in Colorectal Cancer Patients | Full Text | References | PDF (3.6 MB) | EPUB
  • 145 Views
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Article
Discovery and Development of a Novel mPGES-1/5-LOX Dual Inhibitor LFA-9 for Prevention and Treatment of Chronic Inflammatory Diseases
Nagendra Sastri Yarla, Gopal Pathuri, Hariprasad Gali, Simon Terzyan, Janani Panneerselvam, Parthasarathy Chandrakesan, Marcus Tullius Scotti, Courtney Houchen, Venkateshwar Madka & Chinthalapally V Rao
Pages: 1261-1278
Published online: 31 Dec 2020
AbstractforDiscovery and Development of a Novel mPGES-1/5-LOX Dual Inhibitor LFA-9 for Prevention and Treatment of Chronic Inflammatory Diseases | Full Text | References | PDF (8.3 MB) | EPUB
  • 324 Views
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Article
YAP Deficiency Attenuates Pulmonary Injury Following Mechanical Ventilation Through the Regulation of M1/M2 Macrophage Polarization
Qiong Luo, Jing Luo & Yanlin Wang
Pages: 1279-1290
Published online: 31 Dec 2020
AbstractforYAP Deficiency Attenuates Pulmonary Injury Following Mechanical Ventilation Through the Regulation of M1/M2 Macrophage Polarization | Full Text | References | PDF (7.3 MB) | EPUB
  • 171 Views
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Review

Review Article
Laryngopharyngeal Reflux and Inflammatory Responses in Mucosal Barrier Dysfunction of the Upper Aerodigestive Tract
Danling Liu, Tingting Qian, Shan Sun & Jack J Jiang
Pages: 1291-1304
Published online: 05 Jan 2021
AbstractforLaryngopharyngeal Reflux and Inflammatory Responses in Mucosal Barrier Dysfunction of the Upper Aerodigestive Tract | Full Text | References | PDF (2.4 MB) | EPUB
  • 271 Views
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Review Article
Genetic Risk Factors for Idiopathic Pulmonary Fibrosis: Insights into Immunopathogenesis
Jacob E Michalski & David A Schwartz
Pages: 1305-1318
Published online: 05 Jan 2021
AbstractforGenetic Risk Factors for Idiopathic Pulmonary Fibrosis: Insights into Immunopathogenesis | Full Text | References | PDF (7.2 MB) | EPUB
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