Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Volume 25, Issue 5-6 (2024)

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Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Volume 25, Issue 5-6 (2024)

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Review Articles

Review Article
Artificial intelligence for screening and diagnosis of amyotrophic lateral sclerosis: a systematic review and meta-analysis
Tungki Pratama Umar, Nityanand Jain, Manthia Papageorgakopoulou, Rahma Sameh Shaheen, Jehad Feras Alsamhori, Muhammad Muzzamil & Andrejs Kostiks
Pages: 425-436
Published online: 02 Apr 2024
AbstractforArtificial intelligence for screening and diagnosis of amyotrophic lateral sclerosis: a systematic review and meta-analysis | Full Text | References | PDF (2 MB) | EPUB
  • 222 Views
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Review Article
What is the extent of reliability and validity evidence for screening tools for cognitive and behavioral change in people with ALS? A systematic review
Lyndsay Didcote, Silia Vitoratou, Ammar Al-Chalabi & Laura H. Goldstein
Pages: 437-451
Published online: 28 Feb 2024
AbstractforWhat is the extent of reliability and validity evidence for screening tools for cognitive and behavioral change in people with ALS? A systematic review | Full Text | References | PDF (1,019.7 KB) | EPUB | Supplemental
  • 610 Views
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Open Access

Clinical

Article
Neutrophil-to-lymphocyte ratio at diagnosis as a biomarker for survival of amyotrophic lateral sclerosis
Robert J. Nona, Robert D. Henderson & Pamela A. McCombe
Pages: 452-464
Published online: 14 May 2024
AbstractforNeutrophil-to-lymphocyte ratio at diagnosis as a biomarker for survival of amyotrophic lateral sclerosis | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 294 Views
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Open Access
Article
Peripheral immunity relate to disease progression and prognosis in amyotrophic lateral sclerosis
Qirui Jiang, Qianqian Wei, Lingyu Zhang, Tianmi Yang, Junyu Lin, Yi Xiao, Chunyu Li, Yanbing Hou, Ruwei Ou, Kuncheng Liu, Bi Zhao, Ying Wu, Xiaohui Lai & Huifang Shang
Pages: 465-474
Published online: 25 Jan 2024
AbstractforPeripheral immunity relate to disease progression and prognosis in amyotrophic lateral sclerosis | Full Text | References | PDF (651.4 KB) | EPUB | Supplemental
  • 94 Views
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Article
Dyspnea (breathlessness) in amyotrophic lateral sclerosis/motor neuron disease: prevalence, progression, severity, and correlates
Carolyn A. Young, Amina Chaouch, Christopher J. Mcdermott, Ammar Al-Chalabi, Suresh K. Chhetri, Kevin Talbot, Timothy Harrower, Richard W. Orrell, Joe Annadale, C. Oliver Hanemann, Antonio Scalfari, Alan Tennant, Roger Mills & ON BEHALF OF THE TONIC-ALS STUDY GROUP
Pages: 475-485
Published online: 11 Mar 2024
AbstractforDyspnea (breathlessness) in amyotrophic lateral sclerosis/motor neuron disease: prevalence, progression, severity, and correlates | Full Text | References | PDF (956.5 KB) | EPUB | Supplemental
  • 713 Views
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Open Access

Cognition and Behaviour

Article
Cognitive reserve in ALS: the role of occupational skills and requirements
Emma Rhodes, Sebleh Alfa, Hannah A. Jin, Lauren Massimo, Lauren Elman, Defne Amado, Michael Baer, Colin Quinn & Corey T. McMillan
Pages: 486-495
Published online: 09 Apr 2024
AbstractforCognitive reserve in ALS: the role of occupational skills and requirements | Full Text | References | PDF (358.9 KB) | EPUB | Supplemental
  • 119 Views
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Article
Implementation of the MiNDToolkit intervention for the management of behavioral symptoms in MND by healthcare professionals: a mixed-methods process evaluation
T. Katangwe-Chigamba, E. Flanagan & E. Mioshi
Pages: 496-505
Published online: 15 May 2024
AbstractforImplementation of the MiNDToolkit intervention for the management of behavioral symptoms in MND by healthcare professionals: a mixed-methods process evaluation | Full Text | References | PDF (542.1 KB) | EPUB | Supplemental
  • 195 Views
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Open Access
Article
An online intervention for carers to manage behavioral symptoms in motor neuron disease (MiNDToolkit): a randomized parallel multi-center feasibility trial
E. Mioshi, K. Grant, E. Flanagan, S. Heal, H. Copsey, R.L. Gould, M. Hammond, L. Shepstone & P.A. Ashford
Pages: 506-516
Published online: 15 May 2024
AbstractforAn online intervention for carers to manage behavioral symptoms in motor neuron disease (MiNDToolkit): a randomized parallel multi-center feasibility trial | Full Text | References | PDF (857.7 KB) | EPUB | Supplemental
  • 328 Views
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Open Access

Epidemiology

Article
Rurality modifies the association between symptoms and the diagnosis of amyotrophic lateral sclerosis
Alexander A. Hart, Andrea Swenson, Nandakumar S. Narayanan & Jacob E. Simmering
Pages: 517-527
Published online: 14 Feb 2024
AbstractforRurality modifies the association between symptoms and the diagnosis of amyotrophic lateral sclerosis | Full Text | References | PDF (572.5 KB) | EPUB | Supplemental
  • 408 Views
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Open Access
Article
Incidence of amyotrophic lateral sclerosis in Chile
Patricia Lillo, Pedro Zitko, Gladys Godoy-Reyes, Gabriela Asenjo, David Sáez, Gonzalo Cea, Pamela Navarrete, Daniel Valenzuela, Ricardo Hughes, Mark Heverin, Giancarlo Logroscino & Orla Hardiman
Pages: 528-532
Published online: 20 Mar 2024
AbstractforIncidence of amyotrophic lateral sclerosis in Chile | Full Text | References | PDF (312.1 KB) | EPUB
  • 91 Views
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Article
Case-control study of environmental toxins and risk of amyotrophic lateral sclerosis involving the national ALS registry
Evelyn O. Talbott, Angela M. Malek, Vincent C. Arena, Fan Wu, Kristen Steffes, Ravi K. Sharma, Jeanine Buchanich, Judith R. Rager, Todd Bear, Caroline A. Hoffman, David Lacomis, Chris Donnelly, Jocelyn Mauna & John E. Vena
Pages: 533-542
Published online: 09 Apr 2024
AbstractforCase-control study of environmental toxins and risk of amyotrophic lateral sclerosis involving the national ALS registry | Full Text | References | PDF (773.8 KB) | EPUB | Supplemental
  • 541 Views
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Open Access
Article
Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study
Stephen A. Goutman, Jonathan Boss, Dae Gyu Jang, Caroline Piecuch, Hasan Farid, Madeleine Batra, Bhramar Mukherjee, Eva L. Feldman & Stuart A. Batterman
Pages: 543-553
Published online: 01 Apr 2024
AbstractforResidential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study | Full Text | References | PDF (1,023.3 KB) | EPUB | Supplemental
  • 253 Views
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Article
Incidence of amyotrophic lateral sclerosis before and during the COVID-19 pandemic: evidence from an 8-year population-based study in Central Italy based on healthcare utilization databases
Federico Maria Sopranzi, Andrea Faragalli, Marco Pompili, Flavia Carle, Rosaria Gesuita & Maria Gabriella Ceravolo
Pages: 554-562
Published online: 01 Apr 2024
AbstractforIncidence of amyotrophic lateral sclerosis before and during the COVID-19 pandemic: evidence from an 8-year population-based study in Central Italy based on healthcare utilization databases | Full Text | References | PDF (602.4 KB) | EPUB | Supplemental
  • 53 Views
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Article
Percutaneous gastrostomy, mechanical ventilation and survival in amyotrophic lateral sclerosis: an observational study in an incident cohort
Giuseppe Borghero, Vincenzo Pierri, Francesca Pili, Antonella Muroni, Tommaso Ercoli, Maria Ida Pateri, Silvy Pilotto, Alessandra Maccabeo, Adriano Chiò & Giovanni Defazio
Pages: 563-569
Published online: 15 May 2024
AbstractforPercutaneous gastrostomy, mechanical ventilation and survival in amyotrophic lateral sclerosis: an observational study in an incident cohort | Full Text | References | PDF (252.2 KB) | EPUB
  • 76 Views
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Biomarkers and Outcome Measures

Article
Longitudinal comparison of the self-administered ALSFRS-RSE and ALSFRS-R as functional outcome measures in ALS
M. Kelley Erb, Narghes Calcagno, Roland Brown, Katherine M. Burke, Zoe A. Scheier, Amrita S. Iyer, Alison Clark, Max P. Higgins, Mackenzie Keegan, Anoopum S. Gupta, Stephen A. Johnson, Sheena Chew & James D. Berry
Pages: 570-580
Published online: 19 Mar 2024
AbstractforLongitudinal comparison of the self-administered ALSFRS-RSE and ALSFRS-R as functional outcome measures in ALS | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 464 Views
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Open Access
Article
Assessing pulmonary function in ALS using electrical impedance tomography
Seward B. Rutkove, Courtney E. McIlduff, Elijah Stommel, Sean Levy, Christy Smith, Hilda Gutierrez, Sarah Verga, Soleil Samaan, Chebet Yator, Ajitesh Nanda, Lisa Pastel, Allaire Doussan, Kathy Phipps, Ethan Murphy & Ryan Halter
Pages: 581-588
Published online: 04 Apr 2024
AbstractforAssessing pulmonary function in ALS using electrical impedance tomography | Full Text | References | PDF (1.3 MB) | EPUB
  • 59 Views
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Genetics

Article
Genetic and in silico analysis of Indian sporadic young onset patient with amyotrophic lateral sclerosis
Saileyee Roychowdhury, Deepika Joshi, Vinay Kumar Singh, Mohammed Faruq & Parimal Das
Pages: 589-599
Published online: 07 Mar 2024
AbstractforGenetic and in silico analysis of Indian sporadic young onset patient with amyotrophic lateral sclerosis | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 88 Views
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Article
Genotype-phenotype association and functional analysis of hnRNPA1 mutations in amyotrophic lateral sclerosis
Xinyi Zhang, Ye Sun, Xinzhe Zhang, Dongchao Shen, Shi Shu, Xunzhe Yang, Mingsheng Liu, Liying Cui, Qing Liu & Xue Zhang
Pages: 600-607
Published online: 08 May 2024
AbstractforGenotype-phenotype association and functional analysis of hnRNPA1 mutations in amyotrophic lateral sclerosis | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 115 Views
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Article
Rapid classification of a novel ALS-causing I149S variant in superoxide dismutase-1
Victoria K. Shephard, Mikayla L. Brown, Bryony A. Thompson, Alisha Harpur & Luke McAlary
Pages: 608-614
Published online: 14 May 2024
AbstractforRapid classification of a novel ALS-causing I149S variant in superoxide dismutase-1 | Full Text | References | PDF (821.9 KB) | EPUB | Supplemental
  • 305 Views
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Open Access

Patient Focus

Article
What do you think caused your ALS? An analysis of the CDC national amyotrophic lateral sclerosis patient registry qualitative risk factor data using artificial intelligence and qualitative methodology
Danielle Boyce, Jaime Raymond, Theodore C. Larson, Eddie Kirkland, D. Kevin Horton & Paul Mehta
Pages: 615-624
Published online: 08 May 2024
AbstractforWhat do you think caused your ALS? An analysis of the CDC national amyotrophic lateral sclerosis patient registry qualitative risk factor data using artificial intelligence and qualitative methodology | Full Text | References | PDF (639.1 KB) | EPUB
  • 816 Views
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Open Access
Article
How the coronavirus pandemic affected the lives of people with ALS and their spouses in the UK from spouses’ perspectives: a qualitative study
Lyndsay Didcote, Ammar Al-Chalabi & Laura H. Goldstein
Pages: 625-633
Published online: 08 May 2024
AbstractforHow the coronavirus pandemic affected the lives of people with ALS and their spouses in the UK from spouses’ perspectives: a qualitative study | Full Text | References | PDF (695.9 KB) | EPUB | Supplemental
  • 199 Views
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Open Access
Article
Patient engagement in research: lessons learned from CAPTURE ALS, a longitudinal observational ALS study
Shelagh K. Genuis, Westerly Luth, Claire Magnussen, Christine Vande Velde, David Taylor, CAPTURE ALS Participant Partner Advisory Council & Wendy S. Johnston
Pages: 634-643
Published online: 22 Mar 2024
AbstractforPatient engagement in research: lessons learned from CAPTURE ALS, a longitudinal observational ALS study | Full Text | References | PDF (857.6 KB) | EPUB
  • 457 Views
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Open Access

Brief Report

Brief Report
Short tandem repeat expansions in LRP12 are absent in cohorts of familial and sporadic amyotrophic lateral sclerosis patients of European ancestry
Lyndal Henden, Liam G. Fearnley, Dean Southwood, Andrew Smith, Dominic B. Rowe, Matthew C. Kiernan, Roger Pamphlett, Melanie Bahlo, Ian P. Blair & Kelly L. Williams
Pages: 644-647
Published online: 10 May 2024
AbstractforShort tandem repeat expansions in LRP12 are absent in cohorts of familial and sporadic amyotrophic lateral sclerosis patients of European ancestry | Full Text | References | PDF (1,011.9 KB) | EPUB
  • 375 Views
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Open Access

ALS Untangled

Case Report
ALSUntangled #75: Portable neuromodulation stimulator therapy
Laurel Officer, Carmel Armon, Paul Barkhaus, Morgan Beauchamp, Michael Benatar, Tulio Bertorini, Robert Bowser, Mark Bromberg, Andrew Brown, Olimpia Mihaela Carbunar, Gregory T. Carter, Jesse Crayle, Keelie Denson, Eva Feldman, Timothy Fullam, Terry Heiman-Patterson, Carlayne Jackson, Sartaj Jhooty, Danelle Levinson, Xiaoyan Li, Alexandra Linares, Elise Mallon, Javier Mascias Cadavid, Christopher Mcdermott, Tasnim Mushannen, Lyle Ostrow, Ronak Patel, Gary Pattee, Dylan Ratner, Yuyao Sun, John Sladky, Paul Wicks & Richard Bedlack
Pages: 648-652
Published online: 26 Apr 2024
AbstractforALSUntangled #75: Portable neuromodulation stimulator therapy | Full Text | References | PDF (352.3 KB) | EPUB
  • 462 Views
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Free Access

Correction

Correction
Correction
Page: (I)
Published online: 06 Mar 2024
CitationforCorrection | Full Text | PDF (137.1 KB) | EPUB
  • 49 Views
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Free Access

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