Bioanalysis, Volume 13, Issue 6 (2021)

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Bioanalysis, Volume 13, Issue 6 (2021)

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Commentary

Editorial
The Impact of Decreased LC–MS/MS Run Times on Small Molecule Bioanalysis
Remco Koster, Henk Van der Lijke & Peter Pruim
Pages: 409-413
Published online: 15 Mar 2021
First Page PreviewforThe Impact of Decreased LC–MS/MS Run Times on Small Molecule Bioanalysis | Full Text | References | PDF (180.8 KB) | EPUB
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White Paper

Discussion
2020 White Paper on Recent Issues in Bioanalysis: Vaccine Assay Validation, qPCR Assay Validation, QC for CAR-T Flow Cytometry, NAb Assay Harmonization and ELISpot Validation (Part 3–Recommendations on Immunogenicity Assay Strategies, NAb Assays, Biosimilars and FDA/EMA Immunogenicity Guidance/Guideline, Gene & Cell Therapy and Vaccine Assays)
Bart Corsaro, Tong-yuan Yang, Rocio Murphy, Ivo Sonderegger, Andrew Exley, Sylvie Bertholet, Naveen Dakappagari, Francis Dessy, Fabio Garofolo, Lisa Kierstead, Holger Koch, Ghanashyam Sarikonda, Natasha Savoie, Richard Siggers, Therese Solstad, Yanmei Lu, Mark Milton, Jean-Claude Marshall, Jason DelCarpini, Boris Gorovits, Swati Gupta, Lynne Jesaitis, John Kamerud, Arno Kromminga, Anna Ma, Jim McNally, Haoheng Yan, Bonnie Wu, Daniela Verthelyi, Susan Kirshner, Joao Pedras-Vasconcelos, Manoj Rajadhyaksha, Roland F. Staack, Elana Cherry, Isabelle Cludts, Madeleine Dahlbäck, George R. Gunn, Akiko Ishii-Watabe, Vibha Jawa, Robert Kubiak, Michael Partridge, Marco Petrillo, Samuel O. Pine, Johann Poetzl, Sam Song, Chris Stebbins, Yuling Wu, Lucia Zhang, Sumit Kar, Meina Liang, Mohsen Rajabi Abhari, Becky Schweighardt, Kay Stubenrauch & Yuanxin Xu
Pages: 415-463
Published online: 03 Feb 2021
Abstractfor2020 White Paper on Recent Issues in Bioanalysis: Vaccine Assay Validation, qPCR Assay Validation, QC for CAR-T Flow Cytometry, NAb Assay Harmonization and ELISpot Validation (Part 3–Recommendations on Immunogenicity Assay Strategies, NAb Assays, Biosimilars and FDA/EMA Immunogenicity Guidance/Guideline, Gene & Cell Therapy and Vaccine Assays) | Full Text | References | PDF (944.2 KB) | EPUB
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Free Access

Research Article

Article
Application of Middle-Down Approach in Quantitation and Catabolite Identification of Protein by LC–high-Resolution Mass Spectrometry
Lijuan Kang, Shengsheng Xu, Yongle Pang, Tom Kirchner, Yue-mei Zhang, Wilson Edwards, Raul Camacho, Lisa Norquay, Naidong Weng & Wenying Jian
Pages: 465-479
Published online: 15 Mar 2021
AbstractforApplication of Middle-Down Approach in Quantitation and Catabolite Identification of Protein by LC–high-Resolution Mass Spectrometry | Full Text | References | PDF (3.5 MB) | EPUB | Supplemental
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Methodology

Article
A quantitative LC–MS/MS Approach for Monitoring 2′-Fluoro-2′-Deoxy-D-Glucose Uptake in Tumor Tissue
Wenlin Li, Cathy Zhang, Nanni Huser, Chad Ray, Scott Fountain & Erick Kindt
Pages: 481-491
Published online: 16 Mar 2021
AbstractforA quantitative LC–MS/MS Approach for Monitoring 2′-Fluoro-2′-Deoxy-D-Glucose Uptake in Tumor Tissue | Full Text | References | PDF (995.5 KB) | EPUB
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Review

Review Article
Recent Advances in Chiral Analysis for Biosamples in Clinical Research and Forensic Toxicology
LiZhu Chen, DeQiu Zhu & Ping Xiang
Pages: 493-511
Published online: 15 Mar 2021
AbstractforRecent Advances in Chiral Analysis for Biosamples in Clinical Research and Forensic Toxicology | Full Text | References | PDF (1.2 MB) | EPUB
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Review Article
Innovation in Bioanalytical Strategies and in vitro Drug–drug Interaction Study Approaches in Drug Discovery
Saraswathisreeram Pranush Kumar, Deeki Doma Sherpa, Amit Kumar Sahu, Tarang Jadav, Rakesh Kumar Tekade & Pinaki Sengupta
Pages: 513-532
Published online: 08 Mar 2021
AbstractforInnovation in Bioanalytical Strategies and in vitro Drug–drug Interaction Study Approaches in Drug Discovery | Full Text | References | PDF (476.6 KB) | EPUB
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