Drug Development and Industrial Pharmacy, Volume 42, Issue 8 (2016)

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Drug Development and Industrial Pharmacy, Volume 42, Issue 8 (2016)

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Review Article

Review Article
Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review
Michał Teżyk, Bartłomiej Milanowski, Andrzej Ernst & Janina Lulek
Pages: 1195-1214
Published online: 18 Dec 2015
AbstractforRecent progress in continuous and semi-continuous processing of solid oral dosage forms: a review | Full Text | References | PDF (1.8 MB)
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Research Articles

Article
Development of separation technology for the removal of radium-223 from decayed thorium-227 in drug formulations. Material screening and method development
Janne Olsen Frenvik, Solveig Kristensen & Olav B. Ryan
Pages: 1215-1224
Published online: 07 Dec 2015
AbstractforDevelopment of separation technology for the removal of radium-223 from decayed thorium-227 in drug formulations. Material screening and method development | Full Text | References | PDF (1.3 MB)
  • 333 Views
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Article
Sucralose as co-crystal co-former for hydrochlorothiazide: development of oral disintegrating tablets
Mona F. Arafa, Sanaa A. El-Gizawy, Mohamed A. Osman & Gamal M. El Maghraby
Pages: 1225-1233
Published online: 07 Dec 2015
AbstractforSucralose as co-crystal co-former for hydrochlorothiazide: development of oral disintegrating tablets | Full Text | References | PDF (2.1 MB)
  • 477 Views
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Article
Enhanced oral bioavailability of lurasidone by self-nanoemulsifying drug delivery system in fasted state
Yanfei Miao, Jiqin Sun, Guoguang Chen, Ren Lili & Pingkai Ouyang
Pages: 1234-1240
Published online: 13 Dec 2015
AbstractforEnhanced oral bioavailability of lurasidone by self-nanoemulsifying drug delivery system in fasted state | Full Text | References | PDF (970.1 KB)
  • 470 Views
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Article
In vitro testing of thiolated poly(aspartic acid) from ophthalmic formulation aspects
Mária Budai-Szű cs, Gabriella Horvát, Benjámin Gyarmati, Barnabás Áron Szilágyi, András Szilágyi, Tímea Csihi, Szilvia Berkó, Piroska Szabó-Révész, Michela Mori, Giuseppina Sandri, Maria Cristina Bonferoni, Carla Caramella & Erzsébet Csányi
Pages: 1241-1246
Published online: 07 Dec 2015
AbstractforIn vitro testing of thiolated poly(aspartic acid) from ophthalmic formulation aspects | Full Text | References | PDF (738.6 KB)
  • 189 Views
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Article
Safety studies on intravenous infusion of a potent angiogenesis inhibitor: taurocholate-conjugated low molecular weight heparin derivative LHT7 in preclinical models
Farzana Alam, Seung Rim Hwang, Taslim A. Al-Hilal, Seung Woo Chung, Hak-Soo Kim, Boo-Hyun Kang, Hu-Song Zhang, Seo-Ho Shin, Joo-Young Lee, Min-Soo Kang, Geum-Hee Kwon, Ok-Cheol Jeon, Sang Yoon Kim & Youngro Byun
Pages: 1247-1257
Published online: 14 Dec 2015
AbstractforSafety studies on intravenous infusion of a potent angiogenesis inhibitor: taurocholate-conjugated low molecular weight heparin derivative LHT7 in preclinical models | Full Text | References | PDF (3.1 MB) | Supplemental
  • 254 Views
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Article
Evaluation of the percutaneous absorption of chlorpromazine from PLO gels across porcine ear and human abdominal skin
Hashem Alsaab, Rami M. Alzhrani & Sai H. S. Boddu
Pages: 1258-1266
Published online: 21 Dec 2015
AbstractforEvaluation of the percutaneous absorption of chlorpromazine from PLO gels across porcine ear and human abdominal skin | Full Text | References | PDF (1.2 MB)
  • 237 Views
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Article
Formulation optimization of aprepitant microemulsion-loaded silicated corn fiber gum particles for enhanced bioavailability
Sunil Kamboj & Vikas Rana
Pages: 1267-1282
Published online: 21 Dec 2015
AbstractforFormulation optimization of aprepitant microemulsion-loaded silicated corn fiber gum particles for enhanced bioavailability | Full Text | References | PDF (3.4 MB)
  • 181 Views
  • 4 CrossRef citations
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Article
Gellan gum microspheres crosslinked with trivalent ion: effect of polymer and crosslinker concentrations on drug release and mucoadhesive properties
Fernanda Isadora Boni, Fabíola Garavello Prezotti & Beatriz Stringhetti Ferreira Cury
Pages: 1283-1290
Published online: 29 Jan 2016
AbstractforGellan gum microspheres crosslinked with trivalent ion: effect of polymer and crosslinker concentrations on drug release and mucoadhesive properties | Full Text | References | PDF (975.3 KB)
  • 270 Views
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Article
Formulation and characterization of taste masked ondansetron–magnesium aluminum silicate adsorption systems
Vandana Kharb, Vikas Anand Saharan, Vivek Kharb, Hemant Jadhav & Suresh Purohit
Pages: 1291-1299
Published online: 06 Jan 2016
AbstractforFormulation and characterization of taste masked ondansetron–magnesium aluminum silicate adsorption systems | Full Text | References | PDF (1.7 MB)
  • 153 Views
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Article
Fabrication of novel GMO/Eudragit E100 nanostructures for enhancing oral bioavailability of carvedilol
Sharvil S. Patil, Krishtey Roy, Bhavana Choudhary & Kakasaheb R. Mahadik
Pages: 1300-1307
Published online: 06 Jan 2016
AbstractforFabrication of novel GMO/Eudragit E100 nanostructures for enhancing oral bioavailability of carvedilol | Full Text | References | PDF (1.4 MB)
  • 163 Views
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Article
Effect of liquid-to-solid lipid ratio on characterizations of flurbiprofen-loaded solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) for transdermal administration
Aihua Song, Xiaoshu Zhang, Yanting Li, Xinjuan Mao & Fei Han
Pages: 1308-1314
Published online: 20 Jan 2016
AbstractforEffect of liquid-to-solid lipid ratio on characterizations of flurbiprofen-loaded solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) for transdermal administration | Full Text | References | PDF (999.3 KB)
  • 235 Views
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Article
Formulation and rheological evaluation of ethosome-loaded carbopol hydrogel for transdermal application
Shashank Jain, Niketkumar Patel, Parshotam Madan & Senshang Lin
Pages: 1315-1324
Published online: 28 Jan 2016
AbstractforFormulation and rheological evaluation of ethosome-loaded carbopol hydrogel for transdermal application | Full Text | References | PDF (2.1 MB)
  • 486 Views
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Article
Preparation, optimization, characterization and in vivo pharmacokinetic study of asiatic acid tromethamine salt-loaded solid lipid nanoparticles
Gu Lingling, Zhao Yuan & Lu Weigen
Pages: 1325-1333
Published online: 23 Feb 2016
AbstractforPreparation, optimization, characterization and in vivo pharmacokinetic study of asiatic acid tromethamine salt-loaded solid lipid nanoparticles | Full Text | References | PDF (1.7 MB)
  • 335 Views
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Article
Increased bioavailability of celecoxib under fed versus fasted conditions is determined by postprandial bile secretion as demonstrated in a dynamic gastrointestinal model
Eric Lyng, Robert Havenaar, Prathap Shastri, Lucy Hetsco, Andrew Vick & John Sagartz
Pages: 1334-1339
Published online: 18 Feb 2016
AbstractforIncreased bioavailability of celecoxib under fed versus fasted conditions is determined by postprandial bile secretion as demonstrated in a dynamic gastrointestinal model | Full Text | References | PDF (850.9 KB)
  • 288 Views
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Article
Design and evaluation of mucoadhesive microemulsion for neuroprotective effect of ibuprofen following intranasal route in the MPTP mice model
Surjyanarayan Mandal, Snigdha Das Mandal, Krishna Chuttani, Krutika K Sawant & Bharat Bhushan Subudhi
Pages: 1340-1350
Published online: 24 Jan 2016
AbstractforDesign and evaluation of mucoadhesive microemulsion for neuroprotective effect of ibuprofen following intranasal route in the MPTP mice model | Full Text | References | PDF (1.9 MB)
  • 234 Views
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Article
Nanostructured lipid–carrageenan hybrid carriers (NLCCs) for controlled delivery of mitoxantrone hydrochloride to enhance anticancer activity bypassing the BCRP-mediated efflux
Guixia Ling, Tianhong Zhang, Peng Zhang, Jin Sun & Zhonggui He
Pages: 1351-1359
Published online: 16 Feb 2016
AbstractforNanostructured lipid–carrageenan hybrid carriers (NLCCs) for controlled delivery of mitoxantrone hydrochloride to enhance anticancer activity bypassing the BCRP-mediated efflux | Full Text | References | PDF (1.8 MB)
  • 241 Views
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Article
Continuous low-dose feeding of highly active pharmaceutical ingredients in hot-melt extrusion
Marcos Llusa, Stefan Mohr, Ramona Baumgartner, Amrit Paudel, Gerold Koscher & Johannes Khinast
Pages: 1360-1364
Published online: 24 Jan 2016
AbstractforContinuous low-dose feeding of highly active pharmaceutical ingredients in hot-melt extrusion | Full Text | References | PDF (840.2 KB)
  • 232 Views
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Article
A novel application of electrospinning technique in sublingual membrane: characterization, permeation and in vivo study
Jianting Chen, Xiaoyu Wang, Wenji Zhang, Shihui Yu, Jinwu Fan, Bingchao Cheng, Xinggang Yang & Weisan Pan
Pages: 1365-1374
Published online: 01 Feb 2016
AbstractforA novel application of electrospinning technique in sublingual membrane: characterization, permeation and in vivo study | Full Text | References | PDF (1.7 MB)
  • 258 Views
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