Drug Development and Industrial Pharmacy, Volume 45, Issue 7 (2019)

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Drug Development and Industrial Pharmacy, Volume 45, Issue 7 (2019)

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Research Article

Article
Metronidazole-loaded nanostructured lipid carriers to improve skin deposition and retention in the treatment of rosacea
Ujwala A. Shinde, Shruti J. Parmar & Shuba Easwaran
Pages: 1039-1051
Published online: 30 Apr 2019
AbstractforMetronidazole-loaded nanostructured lipid carriers to improve skin deposition and retention in the treatment of rosacea | Full Text | References | PDF (2.6 MB) | EPUB
  • 340 Views
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Article
The preparation, characterization of Lupeol PEGylated liposome and its functional evaluation in vitro as well as pharmacokinetics in rats
Jun Zhang, Huali Liang, Hui Yao, Zhenpeng Qiu, Xinyan Chen, Xixi Hu, Junjie Hu & Guohua Zheng
Pages: 1052-1060
Published online: 21 Apr 2019
AbstractforThe preparation, characterization of Lupeol PEGylated liposome and its functional evaluation in vitro as well as pharmacokinetics in rats | Full Text | References | PDF (2 MB) | EPUB
  • 337 Views
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Article
Formulation and optimization of intranasal nanolipid carriers of pioglitazone for the repurposing in Alzheimer’s disease using Box-Behnken design
Gifty M. Jojo, Gowthamarajan Kuppusamy, Anindita De & V. V. S. Narayan Reddy Karri
Pages: 1061-1072
Published online: 28 Mar 2019
AbstractforFormulation and optimization of intranasal nanolipid carriers of pioglitazone for the repurposing in Alzheimer’s disease using Box-Behnken design | Full Text | References | PDF (2.1 MB) | EPUB
  • 540 Views
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Article
Development and optimization of self-nanoemulsifying drug delivery systems (SNEDDS) for curcumin transdermal delivery: an anti-inflammatory exposure
Mohammad A. Altamimi, Mohsin Kazi, Mshaan Hadi Albgomi, Abdul Ahad & Mohammad Raish
Pages: 1073-1078
Published online: 15 Apr 2019
AbstractforDevelopment and optimization of self-nanoemulsifying drug delivery systems (SNEDDS) for curcumin transdermal delivery: an anti-inflammatory exposure | Full Text | References | PDF (1.3 MB) | EPUB
  • 357 Views
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Article
Preparation and in vitro/in vivo evaluation of azilsartan osmotic pump tablets based on the preformulation investigation
Nini Li, Ling Fan, Biao Wu, Genlai Dai, Chengjun Jiang, Yan Guo & Dianlei Wang
Pages: 1079-1088
Published online: 25 Mar 2019
AbstractforPreparation and in vitro/in vivo evaluation of azilsartan osmotic pump tablets based on the preformulation investigation | Full Text | References | PDF (1.3 MB) | EPUB
  • 219 Views
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Article
Mannose functionalized plain and endosomolytic nanocomposite(s)-based approach for the induction of effective antitumor immune response in C57BL/6 mice melanoma model
Rajeev Sharma & S. P. Vyas
Pages: 1089-1100
Published online: 26 Mar 2019
AbstractforMannose functionalized plain and endosomolytic nanocomposite(s)-based approach for the induction of effective antitumor immune response in C57BL/6 mice melanoma model | Full Text | References | PDF (3.4 MB) | EPUB | Supplemental
  • 152 Views
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Article
Pharmacokinetic and pharmacodynamic modeling of gut hormone peptide YY(3–36) after pulmonary delivery
Jie Shao, Mong-Jen Chen, Philip J. Kuehl & Guenther Hochhaus
Pages: 1101-1110
Published online: 30 Apr 2019
AbstractforPharmacokinetic and pharmacodynamic modeling of gut hormone peptide YY(3–36) after pulmonary delivery | Full Text | References | PDF (2.1 MB) | EPUB
  • 194 Views
  • 1 CrossRef citations
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Article
Development and validation of a versatile HPLC-DAD method for simultaneous determination of the antiviral drugs daclatasvir, ledipasvir, sofosbuvir and ribavirin in presence of seven potential impurities. Application to assay of dosage forms and dissolution studies
Mostafa M. Baker, Sherif F. Hammad & Tarek S. Belal
Pages: 1111-1119
Published online: 01 Apr 2019
AbstractforDevelopment and validation of a versatile HPLC-DAD method for simultaneous determination of the antiviral drugs daclatasvir, ledipasvir, sofosbuvir and ribavirin in presence of seven potential impurities. Application to assay of dosage forms and dissolution studies | Full Text | References | PDF (987.5 KB) | EPUB | Supplemental
  • 193 Views
  • 12 CrossRef citations
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Article
Solubility advantage of sulfanilamide and sulfacetamide in natural deep eutectic systems: experimental and theoretical investigations
Tomasz Jeliński, Maciej Przybyłek & Piotr Cysewski
Pages: 1120-1129
Published online: 02 Apr 2019
AbstractforSolubility advantage of sulfanilamide and sulfacetamide in natural deep eutectic systems: experimental and theoretical investigations | Full Text | References | PDF (1.4 MB) | EPUB
  • 380 Views
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Article
Chitosan-TPP nanoparticles stabilized by poloxamer for controlling the release and enhancing the bioavailability of doxazosin mesylate: in vitro, and in vivo evaluation
Bader M. Aljaeid, Khalid M. El-Say & Khaled M. Hosny
Pages: 1130-1139
Published online: 03 May 2019
AbstractforChitosan-TPP nanoparticles stabilized by poloxamer for controlling the release and enhancing the bioavailability of doxazosin mesylate: in vitro, and in vivo evaluation | Full Text | References | PDF (2.2 MB) | EPUB
  • 238 Views
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Article
Preparation, characterization and ex vivo–in vivo assessment of candesartan cilexetil nanocrystals via solid dispersion technique using an alkaline esterase activator carrier
Ahmed M. Amer, Ahmed N. Allam & Ossama Y. Abdallah
Pages: 1140-1148
Published online: 21 Apr 2019
AbstractforPreparation, characterization and ex vivo–in vivo assessment of candesartan cilexetil nanocrystals via solid dispersion technique using an alkaline esterase activator carrier | Full Text | References | PDF (1.7 MB) | EPUB
  • 116 Views
  • 3 CrossRef citations
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Article
Exploring the influence of particle shape and air velocity on the flowability in the respiratory tract: a computational fluid dynamics approach
Alaa M. Ali, Ahmed S. Abo Dena, Magdi H. Yacoub & Ibrahim M. El-Sherbiny
Pages: 1149-1156
Published online: 21 Apr 2019
AbstractforExploring the influence of particle shape and air velocity on the flowability in the respiratory tract: a computational fluid dynamics approach | Full Text | References | PDF (2.7 MB) | EPUB
  • 175 Views
  • 3 CrossRef citations
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Article
Preparation and evaluation of optimized zolmitriptan niosomal emulgel
Magdy Ibrahim Mohamed, Aly Ahmed Abdelbary, Soha Mohamed Kandil & Tamer Mohamed Mahmoud
Pages: 1157-1167
Published online: 15 May 2019
AbstractforPreparation and evaluation of optimized zolmitriptan niosomal emulgel | Full Text | References | PDF (2.2 MB) | EPUB
  • 230 Views
  • 17 CrossRef citations
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Article
Solubilization and determination of solution thermodynamic properties of itraconazole in different solvents at different temperatures
Sachin K. Jagdale & Rajesh B. Nawale
Pages: 1168-1180
Published online: 01 May 2019
AbstractforSolubilization and determination of solution thermodynamic properties of itraconazole in different solvents at different temperatures | Full Text | References | PDF (1.9 MB) | EPUB
  • 695 Views
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Article
Design and development of bioinspired calcium phosphate nanoparticles of MTX: pharmacodynamic and pharmacokinetic evaluation
Shweta Pandey, Asiya Mahtab, Vijay Kumar, Farhan Jalees Ahmad, Anita Kamra Verma & Sushama Talegaonkar
Pages: 1181-1192
Published online: 21 Apr 2019
AbstractforDesign and development of bioinspired calcium phosphate nanoparticles of MTX: pharmacodynamic and pharmacokinetic evaluation | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 193 Views
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Article
Central composite rotatable design for optimization of budesonide-loaded cross-linked chitosan–dextran sulfate nanodispersion: characterization, in vitro diffusion and aerodynamic study
Divyanka Shrikant Bodas & Pradum Pundlikrao Ige
Pages: 1193-1204
Published online: 06 May 2019
AbstractforCentral composite rotatable design for optimization of budesonide-loaded cross-linked chitosan–dextran sulfate nanodispersion: characterization, in vitro diffusion and aerodynamic study | Full Text | References | PDF (2.5 MB) | EPUB
  • 169 Views
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Article
The influence of storage relative humidity on aerosolization of co-spray dried powders of hygroscopic kanamycin with the hydrophobic drug rifampicin
Mohammad A. M. Momin, Ian G. Tucker & Shyamal C. Das
Pages: 1205-1213
Published online: 06 May 2019
AbstractforThe influence of storage relative humidity on aerosolization of co-spray dried powders of hygroscopic kanamycin with the hydrophobic drug rifampicin | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 196 Views
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