Drug Metabolism Reviews, Volume 47, Issue 1 (2015)

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Drug Metabolism Reviews, Volume 47, Issue 1 (2015)

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Special Edition Dedicated to Sid Nelson's Contributions to the Field of Drug Metabolism

Obituary

Preface: a special tribute to the memory of Dr. Sidney Nelson
Cyrus Khojasteh & Mingshe Zhu
Pages: 1-3
Published online: 29 Apr 2015
First Page PreviewforPreface: a special tribute to the memory of Dr. Sidney Nelson | Full Text | PDF (1.4 MB)
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Free Access

Review Article

The contributions of Sidney D. Nelson to drug metabolism research
Thomas A. Baillie
Pages: 4-11
Published online: 20 Nov 2014
AbstractforThe contributions of Sidney D. Nelson to drug metabolism research | Full Text | References | PDF (426.5 KB)
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A decades-long investigation of acute metabolism-based hepatotoxicity by herbal constituents: a case study of pennyroyal oil
Perry Gordon & S. Cyrus Khojasteh
Pages: 12-20
Published online: 16 Dec 2014
AbstractforA decades-long investigation of acute metabolism-based hepatotoxicity by herbal constituents: a case study of pennyroyal oil | Full Text | References | PDF (714 KB)
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Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib
Han Kiat Ho, James Chun Yip Chan, Klarissa D. Hardy & Eric Chun Yong Chan
Pages: 21-28
Published online: 02 Feb 2015
AbstractforMechanism-based inactivation of CYP450 enzymes: a case study of lapatinib | Full Text | References | PDF (220 KB)
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Metabolic phenotyping applied to pre-clinical and clinical studies of acetaminophen metabolism and hepatotoxicity
Muireann Coen
Pages: 29-44
Published online: 23 Dec 2014
AbstractforMetabolic phenotyping applied to pre-clinical and clinical studies of acetaminophen metabolism and hepatotoxicity | Full Text | References | PDF (1.5 MB)
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Transcriptional profiling of reactive metabolites for elucidating toxicological mechanisms: a case study of quinoneimine-forming agents
Brendan D. Stamper
Pages: 45-55
Published online: 29 Oct 2014
AbstractforTranscriptional profiling of reactive metabolites for elucidating toxicological mechanisms: a case study of quinoneimine-forming agents | Full Text | References | PDF (400.8 KB)
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Practical approaches to resolving reactive metabolite liabilities in early discovery
Deepak Dalvie, Amit S. Kalgutkar & Weichao Chen
Pages: 56-70
Published online: 20 Nov 2014
AbstractforPractical approaches to resolving reactive metabolite liabilities in early discovery | Full Text | References | PDF (929.8 KB)
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Applications of mass spectrometry in drug metabolism: 50 years of progress
Bo Wen & Mingshe Zhu
Pages: 71-87
Published online: 02 Feb 2015
AbstractforApplications of mass spectrometry in drug metabolism: 50 years of progress | Full Text | References | PDF (488.1 KB)
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