Expert Opinion on Drug Discovery, Volume 11, Issue 1 (2016)

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Expert Opinion on Drug Discovery, Volume 11, Issue 1 (2016)

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Editorial

Editorial
Potential of agricultural fungicides for antifungal drug discovery
Josef Jampilek
Pages: 1-9
Published online: 07 Nov 2015
AbstractforPotential of agricultural fungicides for antifungal drug discovery | Full Text | References | PDF (1.8 MB)
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Free Access

Reviews

Review
Improving treatment of neurodevelopmental disorders: recommendations based on preclinical studies
Judith R Homberg, Evan J Kyzar, Adam Michael Stewart, Michael Nguyen, Manoj K Poudel, David J Echevarria, Adam D Collier, Siddharth Gaikwad, Viktor M Klimenko, William Norton, Julian Pittman, Shun Nakamura, Mamiko Koshiba, Hideo Yamanouchi, Sergey A Apryatin, Maria Luisa Scattoni, David M Diamond, Jeremy FP Ullmann, Matthew O Parker, Richard E Brown, Cai Song & Allan V Kalueff
Pages: 11-25
Published online: 02 Dec 2015
AbstractforImproving treatment of neurodevelopmental disorders: recommendations based on preclinical studies | Full Text | References | PDF (635.5 KB)
  • 705 Views
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Review
A review of animal models of obsessive-compulsive disorder: a focus on developmental, immune, endocrine and behavioral models
Marco Grados, Michael Prazak, Aneeqa Saif & Andrew Halls
Pages: 27-43
Published online: 11 Nov 2015
AbstractforA review of animal models of obsessive-compulsive disorder: a focus on developmental, immune, endocrine and behavioral models | Full Text | References | PDF (310.9 KB)
  • 581 Views
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Review
Mechanistic models enable the rational use of in vitro drug-target binding kinetics for better drug effects in patients
Wilhelmus EA de Witte, Yin Cheong Wong, Indira Nederpelt, Laura H Heitman, Meindert Danhof, Piet H van der Graaf, Ron AHJ Gilissen & Elizabeth C.M. de Lange
Pages: 45-63
Published online: 20 Oct 2015
AbstractforMechanistic models enable the rational use of in vitro drug-target binding kinetics for better drug effects in patients | Full Text | References | PDF (794.3 KB)
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Review
Targeting intrinsically disordered proteins in rational drug discovery
Susmitha Ambadipudi & Markus Zweckstetter
Pages: 65-77
Published online: 07 Nov 2015
AbstractforTargeting intrinsically disordered proteins in rational drug discovery | Full Text | References | PDF (837.1 KB)
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Open Access
Review
New drug design with covalent modifiers
Adebayo A Adeniyi, Ramesh Muthusamy & Mahmoud ES Soliman
Pages: 79-90
Published online: 12 Jan 2016
AbstractforNew drug design with covalent modifiers | Full Text | References | PDF (627.3 KB)
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Review
Transporter assays as useful in vitro tools in drug discovery and development
Donna A. Volpe
Pages: 91-103
Published online: 29 Oct 2015
AbstractforTransporter assays as useful in vitro tools in drug discovery and development | Full Text | References | PDF (525.6 KB)
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Review
Functional protein micropatterning for drug design and discovery
Changjiang You & Jacob Piehler
Pages: 105-119
Published online: 01 Dec 2015
AbstractforFunctional protein micropatterning for drug design and discovery | Full Text | References | PDF (1 MB)
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